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See all EPA publications for Timothy Shafer Include records from any date Include records from any EPA source

Records 1 to 25 of 44 records from [ORD-NHEERL] published between 05/22/2013 and 05/22/2018 from author Timothy Shafer

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2018

Shafer, Tim. In vitro approaches to screening and prioritizing chemicals for potential developmental neurotoxicity. Seminar to Tufts University Department of Bioelectrical Eng, Medford, MA, March 26, 2018.

Lynch, B., C. Grant, C. Mack, AND Tim Shafer. Measurements of in vitro neural network activity are influenced by the number of electrodes in MEAs. SOT 2018, San Antonio, Texas, March 11 - 15, 2018.

2017

Frank, C., J. Brown, K. Wallace, W. Mundy, I. Shah, AND Tim Shafer. : Defining toxicological tipping points with microelectrode array recordings of developing neural networks. 2017 Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Ball, K., C. Grant, W. Mundy, AND Tim Shafer. A multivariate extension of mutual information for growing neural networks. Neural Networks. Elsevier B.V., Amsterdam, Netherlands, 95:29-43, (2017). https://doi.org/10.1016/j.neunet.2017.07.009

Brown, J., B. Lynch, I. Curry-Chisolm, Tim Shafer, AND J. Strickland. Assaying Spontaneous Network Activity and Cellular Viability using Multi-well Microelectrode Arrays. METHODS IN MOLECULAR BIOLOGY. Humana Press Incorporated, Totowa, NJ, 1601:153-170, (2017). https://doi.org/10.1007/978-1-4939-6960-9_13

Freudenrich, T., K. Wallace, D. Haag, L. Saavedra, W. Mundy, J. Davila, T. Sudof, M. Wernig, AND Tim Shafer. Comparison of acute effects of neurotoxic compounds in neural networks from rodent and human neurons using microelectrode arrays. Society of Toxicology 2017 Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017.

Strickland, J., K. Wallace, M. Martin, K. Houck, J. Ross, AND Tim Shafer. Concentration-response assessment of ToxCast Phase II compounds on spontaneous neural network activity in vitro. 2017 Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Bal-Price, A., P. Lein, K. Keil, S. Sethi, Tim Shafer, M. Barenys, E. Fritsche, M. Sachana, AND B. Meek. Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, Netherlands, 59:240-255, (2017).

Johnstone, A., J. Strickland, K. Crofton, C. Gennings, AND Tim Shafer. Effects of an Environmentally-relevant Mixture of Pyrethroid Insecticides on Spontaneous Activity in Primary Cortical Networks on Microelectrode Arrays. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, Netherlands, 60(16):234-239, (2017).

Shafer, Tim. In vitro approaches to screening and prioritization of chemicals for potential developmental neurotoxicity. Pittsburg Conference, Chicago, IL, March 05 - 09, 2017.

Curry-Chisolm, I., K. Wallace, C. Mack, AND Tim Shafer. Loperamide Inhibits the Spontaneous Activity of Neural Networks. Society of Toxicology 2017 annual meeting, Baltimore, MD, March 12 - 16, 2017.

Mack, C., D. Hall, D. Herr, AND Tim Shafer. Low and High-Frequency Field Potentials of Cortical Networks Exhibit Distinct Responses to Chemicals. Experimental Biology 2017, Chicago, Illinois, April 22 - 26, 2017.

Strickland, J., M. Martin, K. Houck, J. Ross, AND Tim Shafer. Screening the ToxCast Phase II library for acute neurotoxicity using cortical neurons grown on multi-well microelectrode array (mwMEA) plates. 2017 International Neurotoxicology Association Meeting, Florianopolis, BRAZIL, May 20 - 24, 2017.

Strickland, J., M. Martin, A. Richard, K. Houck, AND Tim Shafer. Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates. Archives of Toxicology. Springer, New York, NY, 92(1):487-500, (2018). https://doi.org/10.1007/s00204-017-2035-5

Shafer, Tim, C. Frank, J. Brown, AND K. Wallace. Using cortical cultures grown on microelectrode arrays to screen compounds for potential developmental neurotoxicity based on changes in network formation. 10th World Congress of Toxicology, Seattle, Washington, August 20 - 29, 2017.

Shafer, Tim, C. Frank, J. Brown, K. Wallace, AND W. Mundy. Using developing cortical cultures on microelectrode arrays to identify and prioritize compounds based on changes in network formation. 2017 International Neurotoxicity Association Meeting, Florianopolis, N/A, BRAZIL, May 20 - 24, 2017.

2016

Cotterill, E., D. Hall, K. Wallace, W. Mundy, S. Eglen, AND Tim Shafer. Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates. Journal of Biomolecular Screening. SAGE Publications USA, Thousand Oaks, CA, 21(5):510-519, (2016).

Druwe, I., T. Freudenrich, K. Wallace, Tim Shafer, AND W. Mundy. Comparison of Human Induced Pluripotent Stem Cell-Derived Neurons and Rat Primary CorticalNeurons as In Vitro Models of Neurite Outgrowth. Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, 2(1):26-36, (2016).

Frank, C., J. Brown, K. Wallace, W. Mundy, I. Shah, AND Tim Shafer. Defining toxicological tipping points using microelectrode array recordings of developing neural networks. North Carolina Society of Toxicology, RTP, NC, October 25, 2016.

Frank, C., J. Brown, K. Wallace, W. Mundy, I. Shah, AND Tim Shafer. Defining toxicological tipping points using microelectrode array recordings of developing neural networks. American Society for Cellular and Computational Toxicology, RTP, NC, September 29 - 30, 2016.

Brown, J., D. Hall, C. Frank, K. Wallace, W. Mundy, AND Tim Shafer. Editor's highlight: Evaluation of a Microelectrode Array-based Assay for Neural Network Ontogeny using Training Set Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 154(1):126-139, (2016).

Mundy, W., S. Padilla, AND Tim Shafer. Expanding the capability to screen and prioritize chemicals for developmental neurotoxicity. CSS BOSC, RTP, NC, November 16 - 18, 2016.

Strickland, J., W. Lefew, J. Crooks, D. Hall, J. Ortenzio, K. Dreher, AND Tim Shafer. In vitro screening of metal oxide nanoparticles for effects on neural function using cortical networks on microelectrode arrays. Journal of Nanotoxicology. Taylor and Francis, Philadelphia, PA, 10(5):619-28, (2016).

Strickland, J., W. LeFew, J. Crooks, D. Hall, J. Ortenzio, K. Dreher, AND Tim Shafer. In vitro screening of silver nanoparticles and ionic silver using neural networks yields differential effects on spontaneous activity and pharmacological responses. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 355(11):1-8, (2016).

2015

Strickland, J., K. Wallace, P. Valdivia, W. Mundy, AND Tim Shafer. A MULTIPLEXED ASSAY FOR DETERMINATION OF NEUROTOXICANT EFFECTS ON SPONTANEOUS NETWORK ACTIVITY AND CELL VIABILITY FROM MICROELECTRODE ARRAYS. Soxciety of Toxicology Meeting, San Diego, CA, March 22 - 27, 2015.