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See all EPA publications for Sigmund Degitz Include records from any date Include records from any EPA source

Records 1 to 25 of 43 records from [ORD-NHEERL] published between 04/18/2014 and 04/18/2019 from author Sigmund Degitz

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2019

Olker, J., Joe Korte, J. Denny, P. Hartig, M. Cardon, J. O'Flanagan, M. Hornung, AND S. Degitz. In vitro screening assays for chemical inhibition of mammalian and amphibian iodotyrosine deiodinase. Society of Toxicology, Baltimore, MD, March 10 - 14, 2019.

Olker, J., Joe Korte, J. Denny, P. Hartig, M. Cardon, C. Knutsen, P. Kent, J. Christensen, S. Degitz, AND M. Hornung. Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 168(2):430-442, (2019). https://doi.org/10.1093/toxsci/kfy302

2018

Gilbert, M., R. Ford, S. Thomas, S. Spring, W. Oshiro, Pat Kosian, J. Ford, AND S. Degitz. Cortical Brain Malformation and Learning Impairments Induced by Developmental Thyroid Hormone Insufficiency: A Cross-Fostering Study. SOT, Baltimore, MD, March 12 - 16, 2017.

LaLone, C., Dan Villeneuve, J. Doering, B. Blackwell, S. Degitz, A. Williams, AND G. Ankley. Defining the taxonomic domain of applicability for mammalian-based high-throughput screening assays. SETAC Focused Topic, Durham, NC, April 16 - 18, 2018.

OShaughnessy, K., Pat Kosian, J. Ford, W. Oshiro, S. Degitz, AND M. Gilbert. Developmental Thyroid Hormone Insufficiency Induces Cortical Brain Malformation and Learning Impairments: A Cross-Fostering Study. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(1):101-115, (2018).

Haselman, J., Pat Kosian, Joe Korte, A. Olmstead, AND S. Degitz. Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 199:240-251, (2018).

Olker, J., J. Haselman, Pat Kosian, K. Donnay, Joe Korte, C. Blanksma, M. Hornung, AND S. Degitz. Evaluating iodide recycling inhibition as a novel molecular initiating event for thyroid axis disruption in amphibians. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(2):318-331, (2018). https://doi.org/10.1093/toxsci/kfy203

Olker, J., Joe Korte, P. Hartig, M. Cardon, M. Hornung, AND S. Degitz. In Vitro screening for chemical inhibitors of human and amphibian iodotyrosine deiodinase activity. SETAC North America, Sacramento, CA, November 04 - 08, 2018.

Hornung, M., S. Degitz, J. Olker, Joe Korte, J. Denny, S. Laws, T. Stoker, P. Hartig, M. Cardon, D. Hallinger, A. Murr, A. Buckalew, J. Wang, K. Paul-Friedman, AND Steve Simmons. In vitro chemical screening assays to identify thyroid hormone disruptors. SETAC North America Focused Topic Meeting, Durham, NC, April 16 - 18, 2018.

Mayasich, S., J. Denny, Joe Korte, S. Degitz, AND M. Hornung. In vitro screening of Xenopus laevis deiodinase 3 for inhibition by ToxCast chemicals. SETAC North America, Sacramento, CA, November 04 - 08, 2018.

Haselman, J., Pat Kosian, K. Donnay, M. Hornung, Joe Korte, J. Denny, J. Olker, R. Schulte, C. Knutsen, AND S. Degitz. In vivo deiodinase inhibition by iopanoic acid causes thyroid axis disruption and dysmorphogenesis in model amphibian species Xenopus laevis. Society of Toxicology Meeting, San Antonio, TX, March 11 - 15, 2018.

Hornung, M., Joe Korte, J. Olker, J. Denny, C. Knutsen, P. Hartig, M. Cardon, AND S. Degitz. Screening the ToxCast Phase 1 chemical library for inhibition of deiodinase type 1 activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 162(2):570-581, (2018).

Olker, J., Joe Korte, J. Denny, J. Hartig, M. Cardon, C. Knutsen, P. Kent, J. Christensen, S. Degitz, AND M. Hornung. Screening the ToxCast Phase 1, 2, and e1k Chemical Libraries for Inhibition of Deiodinase Type 1, 2 and 3 Enzyme Activity. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.

Olker, J., Joe Korte, J. Denny, P. Hartig, M. Cardon, C. Knutsen, P. Kent, J. Christensen, S. Degitz, AND M. Hornung. Screening the ToxCast Phase 1, 2, and e1k chemical libraries for inhibition of Deiodinase Types 1, 2 and 3 enzyme activity. SETAC Focused Topic Meeting, Durham, NC, April 16 - 18, 2018.

LaLone, C., J. Doering, G. Ankley, S. Degitz, AND Dan Villeneuve. SeqAPASS to evaluate conservation of high-throughput screening targets across non-mammalian species. SETAC Europe, Rome, ITALY, May 13 - 17, 2018.

OShaughnessy, K., C. Wood, R. Ford, Pat Kosian, M. Hotchkiss, S. Degitz, AND M. Gilbert. Thyroid hormone disruption in the fetal and neonatal rat: Predictive hormone measures and bioindicators of hormone action in the developing cortex- ToxSci. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, , 163-179, (2018). https://doi.org/10.1093/toxsci/kfy190

LaLone, C., Dan Villeneuve, J. Doering, B. Blackwell, T. Transue, C. Simmons, J. Swintek, S. Degitz, A. Williams, AND G. Ankley. ToxCast results to identify chemical hazards across species. SETAC North America, Sacramento, CA, November 02 - 08, 2018.

OShaughnessy, K., S. Thomas, Pat Kosian, S. Degitz, AND M. Gilbert. Transient Maternal Hypothyroidism Alters Neural Progenitor Expression Resulting in Abnormal Brain Development. SOT, Baltimore, MD, March 12 - 16, 2017.

Haselman, J., J. Christensen, J. Olker, Pat Kosian, K. Donnay, P. DeGoey, M. Hornung, AND S. Degitz. Use of CRISPR/Cas9-mediated gene disruption in Xenopus tropicalis to evaluate thyroid-related targets of toxicological concern. SETAC North America, Sacramento, CA, November 04 - 08, 2018.

2017

Haselman, J., S. Degitz, M. Hornung, Dan Villeneuve, J. Olker, S. Mayasich, D. Knapen, L. Vergauwen, AND E. Stinckens. A catalog of putative adverse outcome pathways (AOPs) that will enhance the utility of ToxCast high throughput screening data for hazard identification, delivered via a putative AOP knowledgebase and a ToxCast assay annotation file that can be linked with the iCSS dashboard. U.S. EPA Office of Research and Development, Washington, DC, 2017.

Olker, J., K. Donnay, J. Haselman, Pat Kosian, Joe Korte, M. Hornung, AND S. Degitz. A tiered approach to evaluate an iodine recycling inhibition adverse outcome pathway (AOP) in amphibians. Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.

Kosian, Pat, Joe Korte, K. Donnay, R. Ford, J. Haselman, M. Hornung, J. Ford, M. Gilbert, AND S. Degitz. Analysis of thyroid hormones in biological samples using stable isotope dilution liquid chromatography-tandem mass spectrometry. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Haselman, J., J. Nichols, M. Hornung, Pat Kosian, J. Olker, Joe Korte, AND S. Degitz. Computational modeling of the amphibian thyroid axis supported by targeted in vivo testing to advance quantitative adverse outcome pathway development. National Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Olker, J., J. Haselman, Pat Kosian, Joe Korte, M. Hornung, AND S. Degitz. Evaluating iodide recycling inhibition as a novel molecular initiating event for thyroid axis disruption. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Hornung, M., Joe Korte, J. Olker, J. Denny, C. Knutsen, P. Hartig, M. Cardon, AND S. Degitz. In vitro screening for potential chemical inhibitors of deiodinase type 1 activity. Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.