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Records 1 to 25 of 26 records from [ORD-NCCT] from author Stephen Little

2016
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).
2015
Knudsen, T. B., A. M. Richard, P. G. Kothiya, R. S. Judson, K. A. Houck, K. C. Crofton, R. S. Thomas, S. Little, E. S. Hunter, N. C. Baker, C. K. M. Leung, J. Palmer, A. Smith, M. Colwell, P. West, R. Burrier, AND L. Egnash. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT). Presented at Society of Toxicology, San Diego, CA, March 21 - 26, 2015. https://doi.org/10.23645/epacomptox.5178703
2014
Goldsmith, M., C. Grulke, D. Chang, T. Transue, S. Little, J. Rabinowitz, AND R. Tornero-Velez. DockScreen: A database of in silico biomolecular interactions to support computational toxicology. Dataset Papers in Science. Hindawi Publishing Corporation, New York, NY, 2014:1-5, (2014).
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, N. Sipes, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, J. Rabinowitz, M. Linnenbrink, J. Franzosa, P. Kothiya, J. Phuong, K. McLaurin, D. Filer, M. Leung, C. Strope, L. Truong, R. Thomas, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, M. Xia, AND R. Huang. In Vitro Screening of 1877 Industrial and Consumer Chemicals, Pesticides and Pharmaceuticals in up to 782 Assays: ToxCast Phase I and II (SOT). Presented at SOT, Pheonix, AZ, March 23 - 27, 2014. https://doi.org/10.23645/epacomptox.5193274
2011
RABINOWITZ, J. R. AND S. LITTLE. Computational Docking of the Isomers of Nonylphenol to the Ligand Binding Domain of the Estrogen Receptor. Presented at Annual Meeting of the Society of Toxicology, Washington, DC, March 06 - 10, 2011.
2010
VOLARATH, P., S. LITTLE, C. YANG, M. T. MARTIN, D. REIF, AND A. M. RICHARD. Feature Analysis of ToxCast Compounds. Presented at American Chemical Society Fall Meeting, Boston, MA, August 21 - 25, 2010.
RABINOWITZ, J. R., S. LITTLE, T. R. Transue, AND M. GOLDSMITH. The Toxicant-Target Paradigm for Toxicity Screening – Pharmacophore Based Constraints. Presented at Society of Toxicology Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.
2009
RABINOWITZ, J. R., S. LITTLE, AND M. GOLDSMITH. Computational Molecular Modeling Methods Applied to Screening for Toxicity. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 15 - 19, 2009.
KNIGHT, A. W., S. LITTLE, K. A. HOUCK, D. J. DIX, R. JUDSON, A. M. RICHARD, N. MCCARROLL, G. AKERMAN, C. YANG, L. BIRRELL, AND R. M. WALMSLEY. Evaluation of High-throughput Genotoxicity Assays Used in Profiling the US EPA ToxCast Chemicals. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 55(2):188-99, (2009).
LITTLE, S., A. W. Knight, L. Birrell, G. Akerman, N. McCarroll, D. J. DIX, K. A. HOUCK, R. JUDSON, R. J. KAVLOCK, M. T. MARTIN, A. M. RICHARD, C. Yang, AND R. M. Walmsley. High Throughput Genotoxicity Profiling of the US EPA ToxCast Chemical Library. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 15 - 19, 2009.
RABINOWITZ, J. R., S. LITTLE, S. C. LAWS, AND M. GOLDSMITH. Molecular Modeling for Screening Environmental Chemicals for Estrogenicity: Use of the Toxicant-Target Approach . CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 22(9):1594-602, (2009).
RABINOWITZ, J. R., M. GOLDSMITH, AND S. LITTLE. Molecular Modeling to Predict and Understand Chemical Toxicity. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
DIX, D. J., K. A. HOUCK, R. JUDSON, T. B. KNUDSEN, S. LITTLE, M. T. MARTIN, H. M. MORTENSEN, D. REIF, A. M. RICHARD, R. W. SETZER, J. F. WAMBAUGH, A. BEAM, D. ROTROFF, M. WOLF, AND R. J. KAVLOCK. The Second Phase of ToxCast and Initial Applications to Chemical Prioritization. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
2008
RABINOWITZ, J. R., S. LITTLE, AND M. GOLDSMITH. Application of the In Silico Toxicant-Target Approach to Screening a Chemical Library for Estrogenicity. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
RABINOWITZ, J. R., M. GOLDSMITH, S. LITTLE, AND M. PASQUINELLI. Computational Molecular Modeling for Evaluating the Toxicity of Environmental Chemicals: Prioritizing Bioassay Requirements. EHP-TOXICOGENOMICS. Environmental Health Perspectives, Research Triangle Park, NC, 116(5):573-577, (2008).
2007
GOLDSMITH, M., S. LITTLE, D. REIF, AND J. R. RABINOWITZ. DIGGING DEEPER INTO DEEP DATA: MOLECULAR DOCKING AS A HYPOTHESIS-DRIVEN BIOPHYSICAL INTERROGATION SYSTEM IN COMPUTATIONAL TOXICOLOGY. Presented at International Science Forum on Computational Toxicology 2007, RTP, NC, May 21 - 23, 2007.
GOLDSMITH, M., S. LITTLE, K. A. HOUCK, D. J. DIX, AND J. R. RABINOWITZ. In Silico Studies of the Toxcast Chemicals Interacting with Biomolecular targets. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
2006
RABINOWITZ, J. R. AND S. LITTLE. MACROMOLECULAR MODELING TO PREDICT AND UNDERSTAND TOXICITY: THE POLYCYCLIC AROMATIC HYDROCARBONS AS A TEST SYSTEM. Presented at BOARD OF SCIENTIFIC COUNSELORS (BOSC), RTP, NC, June 19 - 20, 2006.
PASQUINELLI, M., S. LITTLE, M. GOLDSMITH, AND J. R. RABINOWITZ. MOLECULAR MODELING AS A TOOL FOR UNDERSTANDING HUMAN HEALTH RISKS. Presented at EPA Science Forum: Your Health, Your Environment, Your Future, Ronald Reagan Bldg, Washington, DC, May 16 - 18, 2006.
RABINOWITZ, J. R., M. PASQUINELLI, K. BROWN, H. FAN, AND S. LITTLE. MOLECULAR MODELING FOR PRIORITIZATION OF TOXICITY BIOASSAYS. Presented at 2006 Annual Biophysical Society Meeting, Salt Lake City, UT, February 18 - 22, 2006.
RABINOWITZ, J. R., M. PASQUINELLI, S. LITTLE, H. FAN, AND K. BROWN. RESEARCH ON THE APPLICATION OF MOLECULAR MODELING METHODS FOR THE PRIORITIZATION OF ASSAY REQUIREMENTS AND CLASSIFICATION OF CHEMICAL IN THE ENVIRONMENT. Presented at European Centre for the Validation of Alternative Methods Workshop, Ispra, ITALY, February 20 - 22, 2006.
PASQUINELLI, M., S. LITTLE, AND J. R. RABINOWITZ. TOXICITY PREDICTION TOOLS FOR ENDOCRINE DISRUPTION. Presented at 2006 Annual Society of Toxicology Meeting, San Diego, CA, March 05 - 09, 2006.
PASQUINELLI, M., S. LITTLE, S. LAWS, AND J. R. RABINOWITZ. VIRTUAL SCREENING FOR ENDOCRINE DISRUPTING COMPOUNDS. Presented at US EPA Endocrine Disruptor Program 2006 Star Progress Review Workshop, RTP, NC, July 13 - 14, 2006.
PASQUINELLI, M., S. LITTLE, S. LAWS, AND J. R. RABINOWITZ. VIRTUAL SCREENING FOR ENDOCRINE DISRUPTING COMPOUNDS. Presented at BOARD OF SCIENTIFIC COUNSELORS (BOSC), RTP, NC, June 19 - 20, 2006.