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Records 1 to 25 of 43 records from [ORD-NCCT] published between 12/17/2012 and 12/17/2017 from author Kevin Crofton

2017
Juberg, D., T. Knudsen, M. Sander, N. Beck, E. Faustman, D. Mendrick, J. Fowle, T. Hartung, R. Tice, E. Lamazurier, R. Becker, S. Fitzpatrick, G. Daston, A. Harill, R. Hines, D. Keller, J. Lipscomb, D. Watson, T. Bahadori, AND K. Crofton. FutureTox III: Bridges for Translation. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 155(1):22-31, (2017).
Baker, N., T. Knudsen, K. Crofton, AND G. Patlewicz. High-throughput literature mining to support read-across predictions of toxicity. In Proceedings, American Society for Cellular and Computational Toxicology, Durham, NC, September 29 - 30, 2016. Society ALTEX Edition, Kuesnacht, Switzerland, 1, (2017).
Harrill, J., M. Martin, K. Houck, R. Judson, K. Crofton, AND R. Thomas. Optimization Of A High-Throughput Transcriptomic (HTTr) Bioactivity Screen In MCF7 Cells Using Targeted RNA-Seq (SOT). Presented at SOT annual meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176789
Paul-Friedman, K., J. Zhao, R. Huang, M. Xia, K. Crofton, AND K. Houck. Screening the Tox21 10K library for thyroid stimulating hormone receptor agonist and antagonist activity (SOT annual meeting). Presented at SOT Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176897
Baker, N., T. Knudsen, A. Williams, K. Crofton, AND G. Patlewicz. Supporting read-across predictions of chemical toxicity using high-throughput text-mining (ACS 2017 Spring meeting ). Presented at ACS 2017 Spring National Meeting, San Francisco, CA, April 02 - 06, 2017. https://doi.org/10.23645/epacomptox.5057962
Baker, N., T. Knudsen, A. Williams, AND K. Crofton. Text-mining strategies to support computational research in chemical toxicity (ACS 2017 Spring meeting). Presented at ACS National Meeting, San Francisco, California, April 03 - 06, 2017. https://doi.org/10.23645/epacomptox.5058016
Crofton, K. Update on NCCT Transcriptomic and Metabolic Retrofit Projects. Endocrine Policy Forum, RTP,NC, October 10, 2017.
Patlewicz, G., N. Baker, T. Knudsen, AND K. Crofton. Using high-throughput literature mining to support read-across predictions of skin sensitization (WC). Presented at 10th World Congress on Alternatives and Animal Use in the Life Sciences, Seattle, WA, August 20 - 24, 2017.
Baker, N., T. Knudsen, K. Crofton, AND G. Patlewicz. Using high-throughput literature mining to support read-across predictions of toxicity (SOT). Presented at 2017 SOT National Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178559
2016
Rosenberg, S., N. Nikolov, M. Dybdahl, Steve Simmons, K. Crofton, Eric Watt, K. Paul Friedman, R. Judson, AND E. Wedebye. A QSAR Model for Thyroperoxidase Inhibition and Screening of a Large Set of Environmental Chemicals (SOT). Presented at SOT Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155810
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Crofton, K. Computational Toxicology in EPA (CS SOT MEETING). Presented at Central States SOT Meeting, Iowa City, IA, November 18, 2016. https://doi.org/10.23645/epacomptox.5056798
Crofton, K. Current Applications and Future Directions for 21st Century Toxicity Testing and Risk Assessment (Washington, DC Modernized TSCA meeting). Presented at Opportunities and Challenges in Using Advanced 21st Century Toxicity Testing and Risk Assessment Methods in a Modernized TSCA, Washington, DC, February 08, 2016. https://doi.org/10.23645/epacomptox.5071234
Rosenberg, S., N. Nikolov, M. Dybdahl, Steve Simmons, K. Crofton, Eric Watt, K. Paul-Friedman, R. Judson, AND E. Wedebye. Development of a QSAR Model for Thyroperoxidase Inhbition and Screening of 72,524 REACH substances - (Eurotox 2016). Presented at EUROTOX 2016, Seville, SPAIN, September 04 - 07, 2016. https://doi.org/10.23645/epacomptox.5189476
Crofton, K., G. Patlewicz, M. Martin, AND R. Judson. EU-ToxRisk Project and NCCT Capabilities (EU-ToxRisk-Tox21 Joint Meeting). EU-ToxRisk-Tox 21 Joint Meeting, Mainz, GERMANY, September 12 - 14, 2016. https://doi.org/10.23645/epacomptox.5071252
Baker, N., T. Knudsen, K. Crofton, AND G. Patlewicz. High-throughput literature mining to support read-across predictions of toxicity (ASCCT meeting). Presented at American Society for Cellular and Computational Toxicology, Research Triangle Park, NC, September 29 - 30, 2016. https://doi.org/10.23645/epacomptox.5071423
Simmons, Steve, Eric Watt, K. Paul-Friedman, K. Houck, R. Judson, M. Hornung, AND K. Crofton. Identification of Chemical Features Linked to Thyroperoxidase Inhibition (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155789
Williams, A., M. Linnenbrink, K. Crofton, AND R. Thomas. Investigating Impact Metrics for Performance for the US EPA National Center for Computational Toxicology (ACS Fall meeting). Presented at ACS, Phildelphia, PA, August 21 - 25, 2016. https://doi.org/10.23645/epacomptox.5058502
Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).
Paul-Friedman, K., Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck, AND Steven O. Simmons. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):160-180, (2016).
Langley, G., I. Adcock, F. Busquet, K. Crofton, E. Csernok, C. Giese, T. Heinonen, K. Herrmann, M. Hofmann-Apitius, B. Landesmann, L. Marshall 11, E. McIvor, A. Muotri, F. Noor, K. Schutte, T. Seidle, A. van de Stolpe, H. Van Esch, C. Willett, AND G. Woszczek. Towards a 21st century roadmap for biomedical research and drug discovery: Consensus report and recommendations. DRUG DISCOVERY TODAY. Elsevier Science Ltd, New York, NY, , 1-13, (2016).
Shah, I., Woodrow Setzer, J. Jack, K. Houck, R. Judson, T. Knudsen, J. Liu, M. Martin, D. Reif, Ann M. Richard, Russell S. Thomas, K. Crofton, David J. Dix, AND Robert J. Kavlock. Using ToxCast data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(7):910-919, (2016).
2015
Crofton, K. Adverse Outcome Pathways: Challenges in Use and Development . Presented at Global Chem Meeting, Baltimore, MD, March 03, 2015. https://doi.org/10.23645/epacomptox.5080000