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Records 1 to 25 of 45 records from [ORD-NCCT] published between 10/20/2012 and 10/20/2017 from author Imran Shah

2017
Sauer, S., M. Tarpley, I. Shah, A. Save, H. Lyerly, S. Patierno, K. Williams, AND G. Devi. Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor negative inflammatory breast cancer cells. CARCINOGENESIS. Oxford University Press, Cary, NC, 38(3):252–260, (2017).
Helman, G., I. Shah, AND G. Patlewicz. Case study of read-across predictions using a Generalized Read-Across (GenRA) Approach (10th World Congress). Presented at 10th World Congress on Alternatives and Animal Use in the Life Sciences, Seattle, WA, August 20 - 24, 2017.
Shah, I. AND T. Antonijevic. Finding Toxicological Tipping Points from High-Content Imaging Data (WC10). Presented at WC10, Seattle, WA, August 20 - 24, 2017.
Antonijevic, T. AND I. Shah. Learning Boolean Networks in HepG2 cells using ToxCast High-Content Imaging Data (SOT annual meeting). Presented at SOT 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178637
Patlewicz, G., G. Helman, AND I. Shah. Navigating Through the Minefield of Read-Across Tools and Frameworks: An Update on Generalised Read-Across (GenRA) (CompTox CoP). Presented at CompTox CoP, RTP, NC, June 22, 2017.
Patlewicz, G., G. Helman, P. Pradeep, AND I. Shah. Navigating through the minefield of read-across tools: A review of in silico tools for grouping. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 3:1-18, (2017).
Patlewicz, G., G. Helman, P. Pradeep, AND I. Shah. Navigating through the minefield of read-across: from research to practical tools (WC10). Presented at 10th World Congress on Alternatives and Animal Use in the Life Sciences, WA, Seattle, August 20 - 24, 2017.
Patlewicz, G., G. Helman, AND I. Shah. Systematic Approaches to Biological/Chemical Read-Across for Hazard Identification. Environmental Mutagenesis and Genomics Society (EMGS), Raleigh,NC, September 09 - 13, 2017.
Hartung, T., R. FitzGerald, P. Jennings, G. Mirams, M. Peitsch, A. ostami-Hodjegan, I. Shah, M. Wilks, AND S. Sturla. Systems Toxicology: Real World Applications and Opportunities. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 30(4):870-882, (2017). https://doi.org/10.1021/acs.chemrestox.7b00003
Frame, Alicia, A. Williams, R. Judson, A. Mageid, G. Patlewicz, I. Shah, J. Wambaugh, J. Smith, K. Mansouri, Chris Grulke, AND J. Edwards. The CompTox Dashboard & Emerging Contaminants in the Superfund Program. Presented at ACS Fall Meeting, Washington,DC, August 20 - 24, 2017. https://doi.org/10.23645/epacomptox.6807212
Williams, A., Chris Grulke, K. Mansouri, J. Smith, J. Fitzpatrick, G. Patlewicz, I. Shah, A. Richard, AND J. Edwards. The EPA Comptox Chemistry Dashboard: A Web-Based Data Integration Hub for Toxicology Data (SOT). Presented at SOT Nat. Meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5176750
Saili, K., T. Zurlinden, T. Antonijevic, I. Shah, AND T. Knudsen. Transcriptome profiling to identify ATRA-responsive genes in human iPSC-derived endoderm for high-throughput point of departure analysis (SOT Annual Meeting). Presented at SOT Annual Meeting, Baltimore, MD, March 11 - 16, 2017. https://doi.org/10.23645/epacomptox.5176909
Thomas, R., D. Zink, L. Loo, K. Houck, H. Yu, I. Shah, F. Ginhoux, AND T. Knudsen. US EPA - A*Star Partnership - Accelerating the Acceptance of Next-Generation Sciences and Their Application to Regulatory Risk Assessment (A*Star Symposium, Singapore). Presented at A*STAR Symposium, Singapore, Singapore, SINGAPORE, February 04 - 08, 2017.
2016
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Patlewicz, G., J. Liu, R. Judson, R. Thomas, AND I. Shah. Building Scientific Confidence in the Development and Evaluation of Read-Across - GenRA: Evaluating local validity for read-across prediction using chemical and biological information (SOT/QSAR conference). Presented at 17th International Conference on QSAR in Environmental and Health Sciences, Miami, FL, June 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5067529
Watford, S., I. Shah, R. Judson, AND M. Martin. Chemical-Gene Interactions from ToxCast Bioactivity Data Expands Universe of Literature Network-Based Associations (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155783
Williams, A., K. Mansouri, T. Martin, Christopher M. Grulke, John F. Wambaugh, R. Judson, A. Richard, G. Patlewicz, AND I. Shah. Data Aggregation, Curation and Modeling Approaches to Deliver Prediction Models to Support Computational Toxicology at the EPA (ACS Fall meeting). Presented at ACS Fall Meeting, Phildelphia, PA, August 21 - 25, 2016.
Williams, A., K. Mansouri, T. Martin, Chris Grulke, J. Wambaugh, R. Judson, G. Patlewicz, I. Shah, AND A. Richard. Delivering The Benefits of Chemical-Biological Integration in Computational Toxicology at the EPA (ACS Fall meeting). Presented at ACS Fall Meeting, Phildelphia, PA, August 21 - 25, 2016. https://doi.org/10.23645/epacomptox.5058490
Shah, I., J. Lin, R. Judson, R. Thomas, AND G. Patlewicz. Generalized Read-Across (GenRA) prediction using chemical and biological information (BOSC). Presented at BOSC CSS Meeting, RTP, NC, November 16 - 18, 2016. https://doi.org/10.23645/epacomptox.5179369
Franzosa, J., J. Liu, R. Thomas, J. Wambaugh, K. Houck, AND I. Shah. Prediction of in vivo hepatotoxicity effects using in vitro transcriptomics data (SOT). Presented at SOT annual meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176498
Shah, I., M. Martin, Chris Grulke, L. Pham, J. Liu, A. Williams, G. Patlewicz, AND R. Thomas. Predictive Models of target organ and Systemic toxicities (BOSC). Presented at CSS BOSC Meeting, RTP, NC, November 16 - 18, 2016. https://doi.org/10.23645/epacomptox.5180278
Shah, I. Predictive Toxicology: Current Status and Future Outlook (EBI-EMBL Programme Workshop on Predicitve Toxicology). Presented at EBI-EMBL Industry Programme Workshop on Predictive Toxicology, Hinxton, UK, November 16, 2016. https://doi.org/10.23645/epacomptox.5056588
Judson, R., A. Williams, I. Shah, G. Patlewicz, Eric Watt, P. Pradeep, S. Chavan, J. Edwards, A. Richard, Chris Grulke, M. Martin, K. Mansouri, D. Smith, J. Smith, J. Vail, J. Lambert, S. Wesselkamper, AND R. Thomas. RapidTox - Tools for Rapid Risk Assessments (BOSC). Presented at BOSC Css Meeting, RTP, NC, November 16 - 18, 2016. https://doi.org/10.23645/epacomptox.5181097