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Records 1 to 25 of 76 records from [ORD-NCCT] published between 03/25/2014 and 03/25/2019 from author Keith Houck

2019
Wetmore, B., R. Clewell, B. Cholewa, B. Parks, S. Pendse, M. Black, K. Mansouri, S. Haider, E. Berg, R. Judson, K. Houck, M. Martin, H. Clewell III, M. Andersen, R. Thomas, AND P. McMullen. Assessing Bioactivity-Exposure Profiles of Fruits and Vegetables in the BioMAP Profiling System. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 54:41-57, (2019). https://doi.org/10.1016/j.tiv.2018.09.006
Li, S., J. Zhao, R. Huang, M. Santillo, K. Houck, AND M. Xia. Characterization of Organophosphorous Pesticides on Acetylcholinesterase Inhibition Using In Vitro Assays with Xenobiotic Metabolic Capability. Presented at Society of Toxicology 58th Annual Meeting & ToxExpo, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.1016/j.tiv.2019.01.002
Borrel, A., R. Huang, M. Xia, A. Simeonov, R. Judson, K. Houck, AND N. Kleinstreuer. Predicting Chemical-Assay Interference Using Tox21 HTS Data. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019.
Simha, A., R. Judson, R. Thomas, N. Baker, X. Howey, C. Marable, N. Kleinstreuer, AND K. Houck. Workflow for Defining Reference Chemicals to Assess Performance of In Vitro Assays. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7874000
2018
Kuo, B., J. Wills, P. White, F. Marchetti, A. Nong, A. Williams, K. Houck, R. Tice, AND C. Yauk. A High-throughput Analytical Framework for Efficient Analysis of In Vitro Micronucleus (MN) Dose-response Data. Health Canada Science Forum, OttawaC, March 08 - 09, 2018. https://doi.org/10.23645/epacomptox.6947897
Houck, K. Chemical Prioritization Methods for Nuclear Receptor Modulators at the U.S. EPA. Presented at EDTA International Symposium, Seoul, N/A, SOUTH KOREA, November 09, 2018. https://doi.org/10.23645/epacomptox.7388282
Xia, M., R. Huang, Q. Shi, W. Boyd, J. Zhao, N. Sun, J. Rice, P. Dunlap, A. Hackstadt, M. Bridge, M. Smith, S. Dai, W. Zheng, P. Chu, D. Gerhold, K. Witt, M. DeVito, J. Freeman, C. Austin, K. Houck, R. Thomas, R. Paules, R. Tice, AND A. Simeonov. Comprehensive analyses and prioritization of Tox21 10K chemicals affecting mitochondrial function by in-depth mechanistic studies. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 126(7):1-16, (2018). https://doi.org/10.1289/EHP2589
Sipes, N., R. Huang, K. Shockley, M. Martin, R. Judson, K. Houck, A. Shapiro, J. Addington, S. Auerbach, H. Hong, R. Paules, AND J. Hsieh. Concordance in Modeling Concentration-Response Data: Tox21 10k Library Pipeline Comparison. Presented at OpenTox USA, RTP, NC, July 11 - 12, 2018.
Sipes, N., R. Huang, K. Shockley, M. Martin, A. Shapiro, J. Addington, S. Auerbach, R. Paules, R. Judson, K. Houck, H. Hong, AND J. Hsieh. Confidence in Fitting and Hitting Concentration-Response Data: Tox21 10k Library Pipeline Comparison. Presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6945911
Mahapatra, D., Jill A. Franzosa, K. Roell, M. Kuenemann, Keith A. Houck, D. Reif, D. Fourches, AND S. Kullman. Confirmation of High-Throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Scientific Reports. Nature Publishing Group, London, Uk, 8(8883):1-16, (2018). https://doi.org/10.1038/s41598-018-27055-3
Flood, S. AND K. Houck. Development and Distribution of Test Method Documentation for ToxCast HTT Assays. Presented at SETAC North America Focused Topic Meeting : High-Throughput Screening, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.6948023
Flood, S. AND K. Houck. Development and Distribution of ToxCast and Tox21 HTS Assay Method Descriptions. CompTox Communities of Practice, RTP,NC, January 25, 2018.
Medvedev, A., M. Moeser, L. Medvedeva, E. Martsen, A. Granick, L. Raines, M. Zeng, S. Makarov Jr., K. Houck, AND S. Makarov. Evaluating biological activity of compounds by transcription factor activity profiling. Science Advances. American Association for the Advancement of Science (AAAS), Washington, DC, 4(9):eaar4666, (2018).
Houck, K. AND A. Bone. Filling in the Gaps: The Role Functional Genomics Can Play in 21st Century Toxicology. Presented at Society of Toxicology Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6946166
Judson, R., K. Paul-Friedman, K. Houck, K. Mansouri, P. Browne, AND N. Kleinstreuer. New Approach Methods for Testing Chemicals for Endocrine Disruption Potential. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 9:40-47, (2018). https://doi.org/10.1016/j.cotox.2018.10.002
Houck, K., A. Bone, K. Paul-Friedman, C. Hsu, S. Sakamuru, M. Xia, R. Huang, V. Soni, D. Stavreva, AND K. Crofton. Screening the 10K Tox21 chemical library for thyroid hormone receptor modulators. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Houck, K. Understanding the Biology and Technology of ToxCast and Tox21 Assays. Society of Environmental Toxicology and Chemistry, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.6265523
Houck, K. Update on the ToxCast Chemical Prioritization Project. Presented at California Breast Cancer Research Program, Oakland, CA, February 12 - 14, 2018. https://doi.org/10.23645/epacomptox.7029203
Houck, K. Use of the ToxCast and Tox21 Screening Strategies in Support of Chemical Prioritization for Risk Assessment. Presented at Presentation at Wageningen University June 2018, Wageningen, N/A, NETHERLANDS, June 18, 2018. https://doi.org/10.23645/epacomptox.7001291
Truong, L. AND K. Houck. Use of the ToxCast and Tox21 Screening Strategies in Support of Chemical Prioritization for Risk Assessment (IEBMC). Presented at International Experimental Biology and Medicine Conference (IEBMC) annual meeting, Chengdu, N/A, CHINA, October 19 - 21, 2018. https://doi.org/10.23645/epacomptox.7335080
2017
Houck, K., C. LaLone, A. Bone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarov. A Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SLAS meeting). Presented at 2017 SLAS meeting, Washington, DC, February 04 - 08, 2017. https://doi.org/10.23645/epacomptox.5181265
Kleinstreuer, N., P. Ceger, Eric Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, AND R. Judson. Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 30(4):946-964, (2017).
Flood, S., K. Houck, AND Chris Grulke. Development of a Context-Rich Database of ToxCast Assay Annotations (SOT). Presented at SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178610
Houck, K. EPA’s ToxCast Program: Update on CBCRP-Relevant Work (CBCRP Annual Meeting). Presented at CBCRP Annual Meeting, Berkeley, California, April 06, 2017. https://doi.org/10.23645/epacomptox.5056819