Office of Research and Development Publications

Records 1 to 14 of 14

2016
Fitzpatrick, J., D. Roberts, AND G. Patlewicz. Is skin penetration a determining factor in skin sensitisation potential and potency? Refuting the notion of a LogKow threshold for Skin Sensitisation. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, , 1-11, (2016).
Shah, I., J. Liu, Richard S. Judson, Russell S. Thomas, AND G. Patlewicz. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 79:12-24, (2016).
Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).
2013
Shen, J., L. Xu, H. Fang, A. M. RICHARD, J. D. Bray, R. JUDSON, G. Zhou, T. J. Colatsky, J. L. Aungst, C. Teng, S. C. Harris, W. Ge, AND S. Y. Dai. EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, 135(2):277-291, (2013).
2012
JUDSON, R. S., M. T. MARTIN, P. P. EGEGHY, S. GANGWAL, D. M. REIF, P. KOTHIYA, M. A. WOLF, T. CATHEY, T. R. TRANSUE, D. SMITH, J. VAIL, A. FRAME, S. MOSHER, E. A. COHEN-HUBAL, AND A. M. RICHARD. Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. MDPI AG, Basel, Switzerland, 13(2):1805-1831, (2012).
2011
MAHADEVAN, B., R. D. SNYDER, M. D. WATERS, R. D. BENZ, R. A. KEMPER, R. R. TICE, AND A. M. RICHARD. Genetic toxicology in the 21st century: Reflections and future directions. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. Wiley Liss, New York, NY, 52(5):339 - 354, (2011).
SEDYHK, A., H. ZHU, H. TANG, L. ZHANG, A. M. RICHARD, I. RUSYN, AND A. TROPSHA. Use of in Vitro HTS-Derived Concentration-Response Data as Biological Descriptors Improves the Accuracy of QSAR Models of in Vivo Toxicity. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(3):364-370, (2011).
2010
KAVLOCK, R. J. AND D. J. DIX. Computational Toxicology as Implemented by the U.S. EPA: Providing High Throughput Decision Support Tools for Screening and Assessing Chemical Exposure, Hazard and Risk. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 1(2-4):197-217, (2010).
2009
Zhu, H., L. Ye, A. M. RICHARD, A. Golbraikh, F. A. Wright, I. Rusyn, AND A. Tropsha. A Novel Two-Step Hierarchial Quantitative Structure-Activity Relationship Modeling Workflow for Predicting Acute Toxicity of Chemicals in Rodents. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 117:1257-1264, (2009).
WILLIAMS, C., M. WOLF, AND A. M. RICHARD. DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages. BIOINFORMATICS. Oxford University Press, Cary, NC, 25(5):692-694, (2009).
Benfenati, E., R. Benigni, D. M. Demarini, C. Helma, D. Kirkland, T. M. Martin, P. Mazzatorta, G. Ouedraogo-Arras, A. M. RICHARD, B. Schilter, W. G. Schoonen, R. D. Snyder, AND C. Yang. Predictive Models for Carcinogenicity and Mutagenicity: Frameworks,State-of-the-Art, and Perspectives. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis Reviews. Taylor & Francis Group, London, Uk, 27(2):57-90, (2009).
WILLIAMS, C., M. WOLF, AND A. M. RICHARD. Toward a Public Toxicogenomics Capability for Supporting Predictive Toxicology: Survey of Current Resources and Chemical Indexing of Experiments in GEO and ArrayExpress. TOXICOLOGICAL SCIENCES. Society of Toxicology, 109(2):358-371, (2009).
2008
RICHARD, A. M., C. Yang, AND R. JUDSON. Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction. Toxicology Mechanisms and Methods. Taylor & Francis, Inc., Philadelphia, PA, 18(2 & 3):103-118, (2008).
2006
RICHARD, A. M., L. SWIRSKY GOLD, AND M. C. NICKLAUS. CHEMICAL STRUCTURE INDEXING OF TOXICITY DATA ON THE INTERNET: MOVING TOWARDS A FLAT WORLD. CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT. BioMed Central Ltd, London, Uk, 9(3):314-325, (2006).