Office of Research and Development Publications

Shen, L., R. Judson, F. Melnikov, J. Roethle, A. Guidanda, J. Zimmerman, AND P. Anastas. A Probablistic Diagram to Guide Chemical Design with Reduced Potency to Incur Cytotoxicity. GREEN CHEMISTRY. Royal Society of Chemistry, Cambridge, Uk, 18:4461-4467, (2016).

Mansouri, K., Chris Grulke, A. Richard, R. Judson, AND A. Williams. An automated curation procedure for addressing chemical errors and inconsistencies in public datasets used in QSAR modeling. SAR AND QSAR IN ENVIRONMENTAL RESEARCH. Taylor & Francis, Inc., Philadelphia, PA, 27(11):911-937, (2016).

Wexler, P., R. Judson, S. de Marcellus, J. De Knecht, AND E. Leinala. Health Effects of Toxicants: Online Knowledge Support. LIFE SCIENCES. Elsevier Science Ltd, New York, NY, 145:284-293, (2016).

Shah, I., J. Liu, Richard S. Judson, Russell S. Thomas, AND G. Patlewicz. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 79:12-24, (2016).

Leung, M., J. Phuong, N. Baker, N. Sipes, G. Klinefelter, M. Martin, K. McLaurin, Woodrow Setzer, S. Darney, R. Judson, AND T. Knudsen. Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(7):1050-1061, (2016).

Dionisio, K., A. Frame, M. Goldsmith, J. Wambaugh, A. Liddell, T. Cathay, D. Smith, J. Vail, A. Ernstoff, P. Fantke, O. Jolliet, AND R. Judson. Exploring consumer pathways and patterns of use for chemicals in the environment. Toxicology Reports. Elsevier B.V., Amsterdam, Netherlands, 2:228-237, (2015).

Shen, J., L. Xu, H. Fang, A. M. RICHARD, J. D. Bray, R. JUDSON, G. Zhou, T. J. Colatsky, J. L. Aungst, C. Teng, S. C. Harris, W. Ge, AND S. Y. Dai. EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 135(2):277-291, (2013).

JUDSON, R., R. J. KAVLOCK, M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, A. M. RICHARD, R. R. TICE, M. WHELAN, M. XIA, R. HUANG, C. P. AUSTIN, G. P. DASTON, T. HARTUNG, J. R. FOWLE III, W. WOOGE, W. TONG, AND D. J. DIX. Perspectives on Validation of High-Throughput Assays Supporting 21st Century Toxicity Testing. Sonja von Aulock (ed.), ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 30(1/13):51-66, (2013).

ROTROFF, D., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, N. SIPES, Y. A. ABASSI, C. JIN, M. STAMPFL, AND R. JUDSON. Real-Time Growth Kinetics Measuring Hormone Mimicry for ToxCast Chemicals in T‑47D Human Ductal Carcinoma Cells . CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 26(7):1097-1107, (2013).

JUDSON, R. S., M. T. MARTIN, P. P. EGEGHY, S. GANGWAL, D. M. REIF, P. KOTHIYA, M. A. WOLF, T. CATHEY, T. R. TRANSUE, D. SMITH, J. VAIL, A. FRAME, S. MOSHER, E. A. COHEN-HUBAL, AND A. M. RICHARD. Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. MDPI, Basel, Switzerland, 13(2):1805-1831, (2012).

KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).

EGEGHY, P. P., R. JUDSON, S. GANGWAL, S. Mosher, D. Smith, J. Vail, AND E. A. COHEN-HUBAL. The Exposure Data Landscape for Manufactured Chemicals. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 414(1):159-166, (2012).

JUDSON, R., H. M. MORTENSEN, I. A. SHAH, T. B. KNUDSEN, AND F. ELLOUMI. Using pathway modules as targets for assay development in xenobiotic screening . Molecular BioSystems. RSC Publishing, Cambridge, Uk, 8(2):531-542, (2012).

JUDSON, R., R. J. KAVLOCK, R. W. SETZER, E. A. COHEN-HUBAL, M. T. MARTIN, T. B. KNUDSEN, K. A. HOUCK, R. S. THOMAS, B. A. WETMORE, AND D. J. DIX. Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 24(4):451-462, (2011).

MORTENSEN, H. M. AND S. EULING. Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier BV, AMSTERDAM, Netherlands, (Online):1-10, (2011).

JUDSON, R., M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, D. ROTROFF, M. XIA, S. SAKAMURU, R. HUANG, P. SHINN, C. P. AUSTIN, R. J. KAVLOCK, AND D. J. DIX. Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(15):5979-5985, (2010).

KAVLOCK, R. J. AND D. J. DIX. Computational Toxicology as Implemented by the U.S. EPA: Providing High Throughput Decision Support Tools for Screening and Assessing Chemical Exposure, Hazard and Risk. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 1(2-4):197-217, (2010).

JUDSON, R. Public Databases Supporting Computational Toxicology. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2):218-31, (2010).

JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, M. T. MARTIN, R. J. KAVLOCK, V. DELLARCO, T. HENRY, T. HOLDERMAN, P. SAYRE, S. TAN, T. CARPENTER, AND E. SMITH. The Toxicity Data Landscape for Environmental Chemicals (journal). ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 117(5):685-95, (2009).

JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, F. Elloumi, M. T. MARTIN, T. Cathey, T. R. Transue, R. SPENCER, AND M. WOLF. ACToR-Aggregated Computational Resource. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 233(1):7-13, (2008).

RICHARD, A. M., C. Yang, AND R. JUDSON. Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction. Toxicology Mechanisms and Methods. Taylor & Francis, Inc., Philadelphia, PA, 18(2 & 3):103-118, (2008).