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Platform presentation at the 41st Veterinary Comparative Respiratory Society meeting on Lung Damage and Repair, Providence RI Oct. 23-25, 2023 October is Children&rsquo;s Health Month. As a vulnerable population, children are often more susceptible to the damaging effects of poll...

This presentation gives a brief overview of key research findings related to extreme heat and health, suitable for an 8-10 minute presentation. We highlight key findings related to urban heat islands, cardiovascular outcomes, and respiratory outcomes, and provide context for the ...

Neurodevelopment is a period vulnerable to various insults, including those produced by environmental compounds, and an understanding of these effects continues to be needed. Although in vitro New Approach Methodologies (NAMs) are being developed to foster efficient assessment of...

The six PFAS we have studied (PFOA, GenX, PFMOAA, PFOS, NBP2, PFHxS) produced multiple common effects across all compounds, however the compounds were not toxicologically identical.&nbsp; Effects common across all compounds included reduced pup and maternal bodyweights, reduced p...

Webinar for CALFIRE Prescribed fire is a forest management strategy for reducing risk of wildfires. This study examined the change in cardiorespiratory health impacts (emergency department visits) that could result from an expected increase in the use of prescribed fire in Califo...

We hypothesized that stress caused by high-temperature housing and episodic subchronic wildfire-related eucalyptus smoke exposure (WFES) would interact to disrupt pulmonary, cardiovascular, and metabolic health. Male Wistar-Kyoto rats (4 weeks of age) were exposed to thermal stre...

1.&nbsp;&nbsp;&nbsp; Introduction A growing number of pollutants are reported to negatively affect the hypothalamus-pituitary-thyroid (HPT) axis. Resorcinol is currently under consideration as a substance of very high concern in the European Union. It is used for a variety of pur...

Burn pits are a method of open-air waste management that was common during military operations in Iraq, Afghanistan, and other regions in Southwest Asia. Veterans returning from deployment have reported respiratory symptoms, potentially from exposure to burn pit smoke, yet compre...

EPA is developing new, rapid methods for monitoring water quality at beaches to determine adequacy of water quality for swimming. The methods being developed rely upon quantitive polymerase chain reaction technology. They will permit real time decisions regarding beach closures...

Altered lake hydrology is an emerging, widespread threat as changing climate conditions and increasing human water use place greater pressure on water resources. Dam and land use management can significantly alter lake water-level regimes and flow characteristics, which in turn c...

This presentation describes the development of a decision support tool, the Priority Response Environmental Screening Tool (PRESTO), that was designed to provide a framework for analyzing geospatial information. The objective of a PRESTO analysis is to assist the U.S. Environment...

Background &amp; Aim: Ethylbenzene is an aromatic hydrocarbon widely used in consumer and industrial applications, including as styrene feedstock and in paints, glues, and fuels. Given that ethylbenzene is one of the most highly emitted hazardous air pollutants, it is relevant to...

<h3>Meeting Objective</h3> <p>To facilitate the independent external peer review of the draft PFAS IRIS assessments, U.S. Environmental Protection Agency (EPA) contracted with ERG to run a public meeting. This website serves as a resource for the peer review activities associa...

Overview presentation of two R Shiny applications. One application is geared towards quality control and consistent formatting of continuous sensor data. The other application allows users to summarize and visualize their continuous sensor data. The presentation provides examples...

Climate change and atmospheric deposition of nitrogen (N) and sulfur (S) impact the health and productivity of forests. Here, we explored the potential impacts of these environmental stressors on ecosystem services provided by future forests in the contiguous U.S. We found that a...

Contamination of surface waters often leads to drinking water contamination, degradation of aquatic biota and their habitat and ultimately the decline of the quality of life for both humans and animals. Pathogen contamination, as determined by bacterial fecal indicators, is the l...

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The Road From Animal Models to New Approach Methods for Protecting Human and Animal Health &nbsp; Barbara L. F. Kaplan1, Alan M. Hoberman2, William Slikker Jr3, Mary Alice Smith4, Emanuela Corsini5, Thomas B. Knudsen6, M. Sue Marty7, Sonya K. Sobrian8, Suzanne C. Fitzpatrick9, Ma...

The US EPA uses exposure and toxicity information and risk assessments to protect human health and the environment from known hazards. However, some of the chemicals we are exposed to are unknown, undetected, and unregulated. Discovering the identity of unknown chemicals with mas...

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This is a lecture presentation to public health students in the Gilling School of Public Pealth at University of North Carolina at Chapel Hill.

On September 1, 2020, EPA published the final regulation, Use of Lead Free Pipes, Fittings, Fixtures, Solder, and Flux for Drinking Water. EPA made&nbsp; the conforming changes to existing regulations based on the Reduction&nbsp; of Lead in Drinking Water Act of 2011 and the Comm...

Histone deacetylase inhibitors (HDACi) are epigenotoxicants that disrupt gene expression by modulating histone acetylation. We developed a transcriptomic biomarker of HDACi in human TK6 cells to address the limitations in tools available for identifying HDACi in chemical screenin...

Background and Purpose: Time series data for environmentally relevant chemicals in body fluids and tissues after an exposure is rarely made available despite their importance for risk assessment. Further, access to in vivo data is crucial for chemical safety evaluation estimate...

A key part of the problem formulation phase of environmental assessment is the development of conceptual model diagrams. These diagrams, which explicitly illustrate hypothesized pathways between sources, stressors, and responses relevant to the focal issue, are used in scoping an...