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Records 1 to 25 of 14970

The Scientific Foundation for Regulating Ozone in Ambient Air
(PRESENTATION) [Presented : Mar 15, 2024]
The Clean Air Act requires the Environmental Protection Agency to set National Ambient Air Quality Standard (NAAQS) to protect the public health and welfare against exposures to the “criteria” air pollutants. EPA has identified six criteria pollutants, including ozone...
Microbial functionalities and immobilization of environmental lead: Biogeochemical and molecular mechanisms and implications for bioremediation
(JOURNAL) [Published : Sep 05, 2023]
The increasing environmental and human health concerns about lead in the environment have stimulated scientists to search for microbial processes as innovative bioremediation strategies for a suite of different contaminated media. In this paper, we provide a compressive synthesis...
Centuries old land use changes influence contemporary biogeochemical groundwater behavior in headwater streams
(PRESENTATION) [Presented : Jun 06, 2024]
Before the era of fossil fuel use, water provided power for industrial processes in the USA through a ubiquitous network of dams and mills. This infrastructure was constructed concurrently with widespread deforestation and sedimentation during the 18th through 20th centuries caus...
Value of Information Case Study: Human Health and Economic Trade-offs Associated with the Timeliness, Uncertainty, and Costs of the Draft EPA Transcriptomic Assessment Product (ETAP)
(PUBLISHED REPORT) [Published : Jun 25, 2024]
Time is an important, but underappreciated component in chemical safety decisions. An estimated 15% of the chemicals in domestic commerce have traditional repeated dose toxicity testing data and even fewer have human health assessments that can be used to inform regulatory action...
Technical Evaluation and Standardization of the Human Thyroid Microtissue Assay (MPS World Summit)
(PRESENTATION) [Presented : Jun 14, 2024]
Presentation at the MPS World Summit conference 2024, Track 2.7: Modeling diversity and population health with MPS. 
U.S. EPA International and National Priorities - 2023
(PRESENTATION) [Presented : May 01, 2023]
International Workshop Presentations and Materials: Environmental exposures and public health.  John will be presenting on the broad topic of Environmental priorities and intervention strategies.  The attached presentations will be provided to the international audience...
Exploring CO2(aq) limitation in temperate seagrass species: interspecific variability and biomass dependency
(PRESENTATION) [Presented : Jun 21, 2024]
Seagrasses are often touted for their ability to remove CO2 from the water and sequester it in the sediments as “Blue Carbon”.  Further, seagrasses have been hypothesized to be refugia for calcifying organisms that are sensitive to coastal acidification.  Ho...
Distribution of Cyanobacteria and Microcystin in Lakes of the U.S. Driven by Combination of Lake, Watershed, and Climate Characteristics
(PRESENTATION) [Presented : Jun 07, 2024]
With increasing concerns about freshwater cyanobacteria blooms, there is a need to identify which waterbodies are at risk for developing these blooms, especially those that produce cyanotoxins. To address this concern, we developed spatial statistical models using the US National...
Quantifying Error Introduced by Spatiotemporal Mismatches in Satellite and In-Situ Data Acquisition in Ocean Color Algorithm Development.
(PRESENTATION) [Presented : Jun 07, 2024]
In-situ measurements of optically active indicators of water quality are used to develop and validate spatiotemporally robust and cost-effective satellite remote sensing algorithms. Outputs from water quality algorithms routinely inform policymaker decisions that impact environme...
Mining, refining, and QSAR analysing the nanoinformatics in EPA NaKnowBase
(JOURNAL) [Published : Apr 17, 2024]
Concerns about the safety of manufacturing and using engineered nanomaterials (ENMs) have been increasing as the technology continues to expand. Efforts have been underway to investigate the potentially harmful effects of ENMs without carrying out the challenging empirical studie...
Using genus-level taxonomy and traits for efficient ecological assessments of diatom condition.
(PRESENTATION) [Presented : Jun 06, 2024]
Develop genus level, trait based multimetric diatom index (MMI) to assess ecological condition of rivers/streams across U.S. Compliment NRSA Macroinvertebrate/Fish MMIs.
Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats
(JOURNAL) [Published : Nov 27, 2023]
Introduction: Acrolein is a significant component of anthropogenic and wildfire emissions, as well as cigarette smoke. Although acrolein primarily deposits in the upper respiratory tract upon inhalation, patterns of site-specific injury in nasal versus pulmonary tissues are not w...
Prescribed Fires, Smoke Exposure, and Hospital Utilization Among Heart Failure Patients
(JOURNAL) [Published : Dec 13, 2023]
Background: Prescribed fires often have ecological benefits, but their environmental health risks have been infrequently studied. We investigated associations between residing near a prescribed fire, wildfire smoke exposure, and heart failure (HF) patients' hospital utilizat...
A workflow for the detection of Vibrio spp. in a tropical estuarine environment via enrichment dependent high throughput sequencing and qPCR methods
(PRESENTATION) [Presented : Jun 17, 2024]
Identification of potential pathogens that present risks to human health in recreational waters is necessary to advance in-depth water quality assessments. Despite the application of PCR techniques for environmental pathogen detection, only limited information is usually availabl...
Detection of Emergent and Opportunistic Pathogens in the San Juan Bay Estuary system in Puerto Rico
(PRESENTATION) [Presented : Jun 17, 2024]
The San Juan Bay Estuary (SJBE) is an interconnected system of streams, bays, lagoons, and canals located in a highly urbanized area in San Juan, Puerto Rico. Due to the rapid rate of urbanization, some communities across the SJBE have limited access to or are impacted by failure...
Human Gut-Associated ΦB124-14 Bacteriophage-Like Quantitative Real-Time PCR Assays for Sewage Measurement
(PRESENTATION) [Presented : Jun 17, 2024]
The ability to identify human sewage in environmental, municipal storm system drains, and other waste flows is important to protect public health and natural water resources.  A recent study reports the complete genome sequence of ΦB124-14, a bacteriophage capable of inf...
Characterizing the Biofilm of Microplastics Incubated in River Water and Treated Wastewater Effluent
(PRESENTATION) [Presented : Jun 17, 2024]
Microplastics (MPs) in aquatic environments accumulate a biofilm known as the plastisphere, a microbial community unique from that of the surrounding water and from biofilms that form on natural substrates. The plastisphere is known to accumulate pathogens and bacteria with antib...
The Occurrence of Clinically Relevant Antibiotic Resistance Genes and Sewage in Urban Municipal Storm Sewer System Outfall ‘Wet’ and ‘Dry’ Weather Discharges
(PRESENTATION) [Presented : Jun 17, 2024]
Storm sewer system outfall discharges can be a source of human sewage potentially harboring clinically relevant antibiotic resistance (AR) bacteria and their genes.  These drainage networks primarily collect and discharge untreated stormwater from rain events (‘wet&rsq...
Translating nanoEHS data using EPA NaKnowBase and the Resource Description Framework
(JOURNAL) [Published : Mar 08, 2024]
Background: The U.S. Federal Government has supported the generation of extensive amounts of nanomaterials and related nano Environmental Health and Safety (nanoEHS) data, there is a need to make these data available to stakeholders. With recent efforts, a need for improved inter...
Expanding the Application of Sentinel-2 Chlorophyll Monitoring across United States Lakes
(JOURNAL) [Published : May 30, 2024]
Eutrophication of inland lakes poses various societal and ecological threats, making water quality monitoring crucial. Satellites provide a comprehensive and cost-effective supplement to traditional in situ sampling. The Sentinel-2 MultiSpectral Instrument (S2 MSI) offers unique ...
Efficacy of Chemical Disinfectants Against SARS-CoV-2 on High-Touch Surface Materials
(JOURNAL) [Published : Jan 31, 2023]
Aims: This study aimed to provide operationally relevant SARS-CoV-2 surface disinfection efficacy information. Methods and Results: Disinfectants were evaluated against SARS-CoV-2 on material coupons and were tested using Spray (no-touch with contact time) and Spray & Wipe (wipe...
Quantitative fecal source characterization of urban municipal storm sewer system outfall ‘wet’ and ‘dry’ weather discharges
(JOURNAL) [To be published : Aug 01, 2024]
Urban areas are built environments containing substantial amounts of impervious surfaces (e.g., streets, sidewalks, roof tops). These areas often include elaborately engineered drainage networks designed to collect, transport, and discharge untreated stormwater into local surface...
Research to Confront Climate Change Complexity: Intersectionality, Integration, and Innovative Governance
(JOURNAL) [Published : Jun 12, 2024]
Climate impacts increasingly unfold in interlinked systems of people, nature, and infrastructure. The cascading consequences are revealing sometimes surprising connections across sectors and regions, and prospects for climate responses also depend on complex, difficult-to-underst...
Comparison of DNA-based Detection Methods for Wild Pigs in the San Juan Bay Estuary Area
(PRESENTATION) [Presented : Jun 17, 2024]
Wild pigs are an invasive species found globally that pose significant economic impact and a serious risk to local ecosystems, agriculture, and public health. Fecal contamination of water is one of these public health concerns as wild pigs have been shown to carry pathogenic ente...
Modes of action associated with uranium induced adverse effects in bone function and development
(JOURNAL) [Published : Jul 16, 2015]
Uranium, a naturally occurring element used in military and industrial applications, accumulates in the skeletal system of animals and humans. Evidence from animal and in-vitro studies demonstrates that uranium exposure is associated with alterations in normal bone functions. The...