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50
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2022
Carstens, K., A. Carpenter, M. Martin, J. Harrill, T. Shafer, AND K. Friedman. Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 187(1):62-79, (2022). https://doi.org/10.1093/toxsci/kfac018
Schaupp, C., C. Lalone, B. Blackwell, G. Ankley, AND D. Villeneuve. Leveraging ToxCast data and protein sequence conservation to complement aquatic life criteria derivation. Integrated Environmental Assessment and Management. Allen Press, Inc., Lawrence, KS, 19(1):224-238, (2023). https://doi.org/10.1002/ieam.4617
Pronschinske, M., S. Corsi, L. DeCicco, E. Furlong, G. Ankley, B. Blackwell, D. Villeneuve, P. Lenaker, AND M. Nott. Prioritizing Pharmaceutical Contaminants in Great Lakes Tributaries Using Risk-Based Screening Techniques. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 41(9):2221-2239, (2022). https://doi.org/10.1002/etc.5403
Baldwin, A., S. Corsi, O. Stefaniak, L. Loken, D. Villeneuve, G. Ankley, B. Blackwell, P. Lenaker, M. Nott, AND M. Mills. Risk-Based Prioritization of Organic Chemicals and Locations of Ecological Concern in Sediment From Great Lakes Tributaries. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 41(4):1016-1041, (2022). https://doi.org/10.1002/etc.5286
Isaacs, K., P. Egeghy, K. Dionisio, K. Phillips, A. Zidek, C. Ring, J. Sobus, E. Ulrich, B. Wetmore, A. Williams, AND J. Wambaugh. The chemical landscape of high-throughput new approach methodologies for exposure. Journal of Exposure Science and Environmental Epidemiology . Nature Publishing Group, London, Uk, 32:820-832, (2022). https://doi.org/10.1038/s41370-022-00496-9
Patlewicz, G., A. Richard, A. Williams, R. Judson, AND R. Thomas. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 24:100250, (2022). https://doi.org/10.1016/j.comtox.2022.100250
Patlewicz, G. AND I. Shah. Towards systematic read-across using Generalised Read-Across (GenRA). Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 25:100258, (2023). https://doi.org/10.1016/j.comtox.2022.100258
Sheffield, T., J. Brown, S. Davidson-Fritz, K. Friedman, AND R. Judson. tcplfit2: an R-language general purpose concentration-response modeling package. BIOINFORMATICS. Oxford University Press, Cary, NC, 38(4):1157-1158, (2022). https://doi.org/10.1093/bioinformatics/btab779
2021
Cervantes, P. AND C. Corton. A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 34(7):1721-1737, (2021). https://doi.org/10.1021/acs.chemrestox.0c00510
Villeneuve, Dan, B. Blackwell, J. Cavallin, W. Cheng, R. Conolly, D. Feifarek, K. Jensen, M. Kahl, R. Milsk, S. Poole, E. Randolph, T. Saari, AND G. Ankley. Case study in 21st century ecotoxicology: Using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(4):1155-1170, (2021). https://doi.org/10.1002/etc.4968
Shah, I., T. Antonijevic, B. Chambers, J. Harrill, AND R. Thomas. Estimating Hepatotoxic Doses Using High-content Imaging in Primary Hepatocytes. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 183(2):285-301, (2021). https://doi.org/10.1093/toxsci/kfab091
Black, S., J. Nichols, K. Fay, S. Matten, AND S. Lynn. Evaluation and comparison of in vitro intrinsic hepatic clearance rates measured using cryopreserved hepatocytes from humans, rats, and rainbow trout. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 457:152819, (2021). https://doi.org/10.1016/j.tox.2021.152819
Wang, J., A. Richard, A. Murr, A. Buckalew, R. Lougee, Mahmoud A. Shobair, D. Hallinger, S. Laws, AND T. Stoker. Expanded High-Throughput Screening and Chemotype-Enrichment Analysis of the Phase II:e1k ToxCast Library for Human Sodium-Iodide Symporter (NIS) Inhibition. Archives of Toxicology. Springer, New York, NY, 95(5):1723-1737, (2021). https://doi.org/10.1007/s00204-021-03006-2
Harrill, J., L. Everett, D. Haggard, T. Sheffield, J. Bundy, C. Willis, R. Thomas, I. Shah, AND R. Judson. High-Throughput Transcriptomics Platform for Screening Environmental Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 181(1):68-89, (2021). https://doi.org/10.1093/toxsci/kfab009
Franzosa, J., J. Bonzo, J. Jack, Nancy C. Baker, P. Kothiya, R. Witek, P. Hurban, S. Siferd, S. Hester, I. Shah, S. Ferguson, K. Houck, AND J. Wambaugh. High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures. npj Systems Biology and Applications. Springer Nature, New York, NY, 7:Article 7, (2021). https://doi.org/10.1038/s41540-020-00166-2
Alvarez, D., S. Corsi, L. De Cicco, Dan Villeneuve, AND A. Baldwin. Identifying chemicals and mixtures of potential biological concern detected in passive samplers from Great Lakes tributaries using high-throughput data and biological pathways. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(8):2165-2182, (2021). https://doi.org/10.1002/etc.5118
Olker, J., J. Korte, J. Denny, J. Haselman, Philip Hartig, M. Cardon, M. Hornung, AND S. Degitz. In Vitro Screening for Chemical Inhibition of the Iodide Recycling Enzyme, Iodotyrosine Deiodinase. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 71:105073, (2021). https://doi.org/10.1016/j.tiv.2020.105073
Rovida, C., S. Escher, M. Herzler, S. Bennekou, H. Kamp, D. Kroese, L. Maslankiewicz, M. Moné, G. Patlewicz, N. Sipes, L. van Aerts, A. White, T. Yamada, AND B. van de Water. NAM-supported read-across: from case studies to regulatory guidance in safety assessment. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 38(1):140-150, (2021). https://doi.org/10.14573/altex.2010062
Mayasich, S., J. Korte, J. Denny, Philip Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, AND M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 73:105141, (2021). https://doi.org/10.1016/j.tiv.2021.105141
2020
Smith, M., E. Hubal, AND E. Faustman. A Case study on the utility of predictive toxicology tools in alternatives assessments for hazardous chemicals in children’s consumer products. Journal of Exposure Science and Environmental Epidemiology . Nature Publishing Group, London, Uk, 30(1):160-170, (2020). https://doi.org/10.1038/s41370-019-0165-y
Johnstone, A., C. Mack, M. Valdez, T. Shafer, D. Herr, P. Kodavanti, AND R. Lo Pachin. Acute In Vitro Effects on Embryonic Rat Dorsal Root Ganglion (DRG) Cultures by In Silico Predicted Neurotoxic Chemicals: Evaluations on Cytotoxicity, Neurite Length, and Neurophysiology. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 69(104989):1, (2020). https://doi.org/10.1016/j.tiv.2020.104989
Nyffeler, J., C. Willis, R. Lougee, A. Richard, K. Friedman, AND J. Harrill. Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 389:114876, (2020). https://doi.org/10.1016/j.taap.2019.114876
Mansouri, K., N. Kleinstreuer, R. Judson, A. Williams, I. Shah, AND A. Richard. CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 128(2):27002, (2020). https://doi.org/10.1289/EHP5580
Kosnik, M., J. Strickland, S. Marvel, D. Wallis, K. Wallace, A. Richard, D. Reif, AND T. Shafer. Concentration-Response Evaluation of ToxCast Compounds for Multivariate Activity Patterns of Neural Network Function. Archives of Toxicology. Springer, New York, NY, 94:469-484, (2020). https://doi.org/10.1007/s00204-019-02636-x
Sayre, R., J. Wambaugh, AND C. Grulke. Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals. Scientific Data. Springer Nature, New York, NY, 7:122, (2020). https://doi.org/10.1038/s41597-020-0455-1