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Records 26 to 50 of 95 records from author Steven Simmons

2018
Lavrich, K., E. Corteselli, P. Wages, P. Bromberg, Steve Simmons, E. Gibbs-Flournoy, AND J. Samet. Investigating Mitochondrial Dysfunction in Human Lung Cells Exposed to Redox-Active PM Components. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 342:99-107, (2018).
Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Optimization of DNA Barcode Method to Assess Altered Chemical Toxicity due to CYP-mediated Metabolism. SOT 57th Annual meeting, San Antonio, TX, March 11 - 15, 2018.
Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Optimization of DNA barcode method to assess altered chemical toxicity due to CYP-mediated metabolism. North Carolina Academy of Science 2018, NC, Raleigh, March 23 - 24, 2018.
Simmons, Steve. Respirometric Screening and Characterization of Mitochondrial Toxicities Induced by ToxCast Chemicals. Presented at European Society of Toxicology (Eurotox), Brussels, N/A, BELGIUM, September 02 - 05, 2018. https://doi.org/10.23645/epacomptox.7078166
DeGroot, D., R. Thomas, M. Lee, P. Carmichael, Steve Simmons, AND C. Deisenroth. Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence Using Alginate Immobilization of Metabolic Enzymes. Presented at SOT Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.
DeGroot, D., R. Thomas, M. Lee, P. Carmichael, Steve Simmons, AND C. Deisenroth. Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence Using Alginate Immobilization of Metabolic Enzymes (AIME). SETAC High Throughput Screening and Environmental Risk Assessment, Durham,NC, April 16 - 18, 2018.
Simmons, Steve. mRNA Transfection Retrofits Cell-based Assays with Xenobiotic Metabolism. Presented at Computational Toxicology Communities of Practice, Research Triangle Park, NC, February 22, 2018. https://doi.org/10.23645/epacomptox.7075028
DeGroot, D., A. Swank, R. Thomas, M. Strynar, M. Lee, P. Carmichael, AND Steve Simmons. mRNA transfection retrofits cell-based assays with xenobiotic metabolism. JOURNAL OF PHARMACOLOGICAL & TOXICOLOGICAL METHODS. Elsevier Science Ltd, New York, NY, 92:77-94, (2018). https://doi.org/10.1016/j.vascn.2018.03.002
2017
DeGroot, D., R. Thomas, AND Steve Simmons. Chemical Screening for Bioactivated Electrophilic Metabolites Using Alginate Immobilization of Metabolic Enzymes (AIME) (SOT). Presented at SOT Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5181259
Hallinger, D., A. Murr, A. Buckalew, Steve Simmons, T. Stoker, AND S. Laws. Development of a Screening Approach to Detect Thyroid Disrupting Chemicals that Inhibit the Human Sodium/Iodide Symporter (NIS). TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 40:66-78, (2017).
Woolard, E., G. Carswell, Steve Simmons, M. Babic, AND B. Chorley. Establishing a Cell-based Assay for Assessment of Cellular Metabolism on Chemical Toxicity. GEMS annual fall meeting, RTP, NC, November 07, 2017.
Simmons, Steve. From High-Throughput Toxicity Testing to Building Better Models to Predict Endocrine Disruption: Thyroperoxidase Case Study. Presented at Presentation given at North Carolina State University Oct 31, 2017, Raleigh, NC, October 31, 2017.
Pegram, R., A. Teal, Steve Simmons, T. Ross, J. Campbell, D. DeMarini, AND B. Chorley. Genotoxicity of Brominated Trihalomethanes in Human Bladder Cells. Gordon Research Conference on Drinking Water Disinfection Byproducts, South Hadley, MA, July 30 - August 04, 2017.
Pegram, R., E. Kenyon, Steve Simmons, D. DeMarini, B. Chorley, A. Teal, AND T. Ross. Molecular Mechanisms by Which Chlorinated Water Causes Bladder Cancer. 48th Annual Meeting of the Environmental Mutagenesis and Genomics Society, Raleigh, North Carolina, September 09 - 13, 2017.
Simmons, Steve. Retrofit Strategies for Incorporating Xenobiotic Metabolism into High Throughput Screening Assays (EMGS). Presented at 48th Annual Meeting of the Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 09 - 13, 2017.
Simmons, Steve AND D. DeGroot. Retrofitting High-Throughput In Vitro Assays for Metabolic Competence. Presented at Endocrine Disruptor Screening Program (EDSP) Workgroup, Research Triangle Park, NC, November 14, 2017. https://doi.org/10.23645/epacomptox.6860207
2016
DeGroot, D., R. Thomas, AND Steve Simmons. Metabolism Retrofit Strategies for ToxCast Assays (BOSC). Presented at BOSC CSS Meeting, RTP, NC, November 16 - 18, 2016. https://doi.org/10.23645/epacomptox.5179093
Simmons, Steve. A High-Throughput Screening Assay to Detect Thyroperoxidase Inhibitors (Teratology Society). Presented at 56th Annual Meeting of The Teratology Society, San Antonio, TX, June 25 - 29, 2016. https://doi.org/10.23645/epacomptox.5077495
Rosenberg, S., N. Nikolov, M. Dybdahl, Steve Simmons, K. Crofton, Eric Watt, K. Paul Friedman, R. Judson, AND E. Wedebye. A QSAR Model for Thyroperoxidase Inhibition and Screening of a Large Set of Environmental Chemicals (SOT). Presented at SOT Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155810
DeGroot, D., R. Thomas, AND Steve Simmons. Alginate Immobilization of Metabolic Enzymes (AIME) for High-Throughput Screening Assays (SOT). Presented at SOT 55th Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176546
Pegram, R., J. Campbell, Steve Simmons, T. Ross, D. DeMarini, AND B. Chorley. BROMINATED TRIHALOMETHANE (BrTHM) TOXICITY IN HUMAN BLADDER CELL LINES. 2016 Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016.
Murr, A., D. Hallinger, A. Buckalew, Steve Simmons, T. Stoker, AND S. Laws. DEVELOPMENT OF AN IN VITRO RADIOACTIVE IODIDE UPTAKE ASSAY (RAIU) WITH HUMAN NIS-EXPRESSING HEK293T-EPA CELL LINE. To be Presented at Society of Toxicology, New Orleans, LA, March 13 - 17, 2016.
Rosenberg, S., N. Nikolov, M. Dybdahl, Steve Simmons, K. Crofton, Eric Watt, K. Paul-Friedman, R. Judson, AND E. Wedebye. Development of a QSAR Model for Thyroperoxidase Inhbition and Screening of 72,524 REACH substances - (Eurotox 2016). Presented at EUROTOX 2016, Seville, SPAIN, September 04 - 07, 2016. https://doi.org/10.23645/epacomptox.5189476
Simmons, Steve, Eric Watt, K. Paul-Friedman, K. Houck, R. Judson, M. Hornung, AND K. Crofton. Identification of Chemical Features Linked to Thyroperoxidase Inhibition (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155789
Paul-Friedman, K., Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck, AND Steven O. Simmons. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):160-180, (2016).