Science Inventory

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GAVETT, S. H., A. M. JARABEK, E. W. Tewksbury, E. Bermudez, V. A. Wong, E. Gross-Bermudex, G. A. Wilson, H. G. Wall, AND D. E. Dodd. TWO-WEEK INHALATION EXPOSURE OF RATS TO LIBBY AMPHIBOLE (LA) AND AMOSITE ASBESTOS. Presented at 50th Annual Society of Toxicology Meeting, Washington, DC, March 06 - 10, 2010.

Peay, T. S., J. MCKEE, G. A. Wilson, M. H. George, R. H. JASKOT, D. G. ROSS, T. MOORE, AND A. M. JARABEK. ACUTE STUDIES OF INHALED CHLORINE IN F344 RATS SUGGEST ALTERNATIVE TO HABER'S RULE FOR RISK EXTRAPOLATIONS. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.

JARABEK, A. M. AND H. R. KEHRL. Epithelial perturbation by inhaled chlorine: Multi-scale mechanistic modeling in rats and humans. Presented at American Association for Aerosol Research 2010 International Conference, San Diego, CA, March 22 - 26, 2010.

Asgharian, B., A. M. JARABEK, S. H. GAVETT, AND O. T. Price. Fiber inhalability and head deposition in rats and humans. Presented at 29th Annual Meeting of the American Association for Aerosol Research, Portland, OR, October 25 - 29, 2010.

JARABEK, A. M., J. MCKEE, G. A. Wilson, M. H. George, R. H. JASKOT, D. G. ROSS, T. MOORE, AND T. S. Peay. STOP-EXPOSURE STUDIES OF INHALED CHLORINE PROVIDE IMPORTANT INSIGHTS ON PATHOGENESIS. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.

George, M. H., J. MCKEE, G. Wilson, R. H. JASKOT, D. G. ROSS, T. MOORE, T. Peay, AND A. M. JARABEK. SUBACUTE MECHANISTIC STUDIES OF INHALED CHLORINE IN F344 RATS. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.

MADDEN, M. C. AND A. M. JARABEK. Biofuels and the bay: Characterizing health and ecosystem impacts in the Chesapeake. Presented at Society of Toxicology , Baltimore, MD, March 15 - 19, 2009.

POTTENGER, L. H., A. M. JARABEK, M. HIMMELSTEIN, P. J. BOOGAARD, L. S. ANDREWS, D. CASCIANO, J. CADET, M. EMBRY, P. B. FARMER, J. KIM, J. PRESTON, V. REDDY, R. S. SCHOENY, D. SHUKER, J. SKARE, J. A. SWENBERG, G. M. WILLIAMS, AND E. ZEIGER. Creating Context for the Use of DNA Adduct Data in Risk Assessment. Presented at 2009 Annual Society of Toxicology Meeting, Baltimore, MD, March 15 - 19, 2009.

JARABEK, A. M., L. H. Pottenger, D. Casciano, M. Embry, J. Kim III, J. PRESTON, M. M. Vijayaraj, R. Schoeny, D. Shuker, J. Skare, J. A. SWENBERG, G. Williams, AND E. Zeiger. Creating context for the use of DNA adduct data in cancer risk assessment: I. Proposed framework for data organization *. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, 39(8):659-678, (2009).

EDWARDS, S. W., J. PRESTON, A. GELLER, A. M. JARABEK, D. C. WOLF, E. A. COHEN-HUBAL, G. T. ANKLEY, H. A. EL-MASRI, I. A. SHAH, J. R. FOWLE, J. A. ROSS, J. W. NICHOLS, K. M. CROFTON, M. J. DEVITO, T. V. RAMABHADRAN, R. J. KAVLOCK, E. S. HUNTER, T. B. KNUDSEN, AND W. R. MUNDY. Toxicity pathway-based mode of action modeling for risk assessment. Presented at Symposium on toxicity pathway-based risk assessment, washington dc, DC, May 11 - 13, 2009.

Sochaski, M., J. Murphy, A. M. JARABEK, AND M. Anderson. 3-Chlorotyrosine and 3,5-Dichlorotyrosine as biomarkers of respiratory tract exposure to chlorine gas. JOURNAL OF ANALYTICAL TOXICOLOGY. Preston Publications Incorporated, Niles, IL, 32(1):99-105, (2008).

TEEGUARDEN, J. G., M. S. BOGDANFFY, T. R. COVINGTON, Y. M. TAN, AND A. M. JARABEK. A PBPK MODEL FOR EVALUATING THE IMPACT OF ALDEHYDE DEHYDROGENASE POLYMORPHISMS ON COMPARATIVE RAT AND HUMAN NASAL TISSUE ACETALDEHYDE DOSIMETRY. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 20(4):375-90, (2008).

Teegaurden, J. G., M. S. Bogdanffy, T. R. Covington, Y. Tan, AND A. M. JARABEK. A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry*. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 20(4):375-390, (2008).

FOOS, B., M. MARTY, J. SCHWARTZ, W. BENNETT, J. MOYA, A. M. JARABEK, AND A. SALMON. FOCUSING ON CHILDREN’S INHALATION DOSIMETRY AND HEALTH EFFECTS FOR RISK ASSESSMENT: AN INTRODUCTION. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH. Taylor & Francis, Inc., Philadelphia, PA, 71(3):149-65, (2008).

Zhang, Q., J. Pi, C. Woods, A. M. JARABEK, H. J. Clewell III, AND M. Anderson. Hormesis and adaptive cellular control systems. Dose-Response. International Hormesis Society, Amherst, MA, 19(6):196-208, (2008).

GINSBERG, G. L., B. ASGHARIAN, J. S. KIMBELL, J. S. ULTMAN, AND A. M. JARABEK. MODELING APPROACHES FOR ESTIMATING THE DOSIMETRY OF INHALED TOXICANTS IN CHILDREN. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH. Taylor & Francis, Inc., Philadelphia, PA, 71(3):166-95, (2008).

BENNETT, W., K. ZEMAN, AND A. M. JARABEK. Nasal Contribution to Breathing and Fine Particle Deposition in Children Versus Adults. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 71(3):227-37, (2008).

JARABEK, A. M., J. D. SCHROETER, M. E. ANDERSEN, AND J. S. KIMBELL. A HYBRID CFD-PBPK MODEL OF INHALED CHLORINE GAS UPTAKE AND TISSUE DOSIMETRY IN THE ISOLATED UPPER RESPIRATORY TRACT (URT) OF F344 RATS. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

CRAWFORD-BROWN, D. J. AND A. M. JARABEK. CREATING A DECISION CONTEXT FOR COMPARATIVE ANALYSIS AND CONSISTENT APPLICATION OF INHALATION DOSIMETRY MODELS IN CHILDREN'S RISK ASSESSMENT . Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

FOOS, B., M. MARTY, J. SCHWARTZ, W. BENNETT, J. MOYA, A. M. JARABEK, AND A. SALMON. Focusing On Children's Inhalation Dosimetry And Health Effects For Risk Assessment: An Introduction (Journal). JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH. Taylor & Francis, Inc., Philadelphia, PA, 71(3):149-165, (2007).

JARABEK, A. M., J. SCHROETER, M. E. ANDERSEN, AND J. S. KIMBELL. MODULAR APPLICATION OF COMPUTATIONAL MODELS OF INHALED REACTIVE GAS DOSIMETRY FOR RISK ASSESSMENT OF RESPIRATORY TRACT TOXICITY: CHLORINE . Presented at 2007 EPA International Science Forum on Computational Toxicology, Research Triangle Park, NC, May 21 - 23, 2007.

ZHU, L., Y. ZHAO, J. PI, M. E. ANDERSEN, A. M. JARABEK, AND Y. CHEN. PROINFLAMMATORY OXIDANT HYPOCHLOROUS ACID (HOCL) INDUCES DUAL SIGNALING PATHWAYS IN AIRWAY EPITHELIAL CELLS. Presented at American Thoracic Society Annual Meeting, San Francisco, CA, May 18 - 23, 2007.

TEWKSBURY, E. W., O. R. MOSS, M. A. SOCHASKI, C. U. PARKINSON, E. A. GROSS, R. A. JAMES, M. E. ANDERSEN, AND A. M. JARABEK. RESPIRATORY RESPONSE AND INTERNAL TISSUE DOSE OF INHALED CHLORINE IN THE RESPIRATORY TRACT OF B6C3F1 MICE: SEX AND STRAIN COMPARISONS . Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

PARKINSON, C. U., O. R. MOSS, M. SOCHASKI, E. W. TEWKSBURY, E. A. GROSS, M. E. ANDERSEN, AND A. M. JARABEK. RESPIRATORY RESPONSE AND INTERNAL TISSUE DOSE OF INHALED CHLORINE IN THE RESPIRATORY TRACT OF F344 RATS: SEX AND SPECIES COMPARISONS. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

ROBERTS, K. C., O. R. MOSS, M. SOCHASKI, R. A. JAMES, E. A. GROSS, M. E. ANDERSEN, AND A. M. JARABEK. UPTAKE AND INTERNAL DOSIMETRY OF INHALED CHLORINE IN THE ISOLATED UPPER RESPIRATORY TRACT (URT) OF F344 RATS. . Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.