Science Inventory

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WINNIK, W. M., O. Alzate, M. E. BRUNO, L. BURGOON, Y. GE, G. R. KLINEFELTER, PRASADA RAO S. KODAVANTI, J. B. Robinette, J. D. SUAREZ, AND K. WALLACE. Improved method for identification of low abundance proteins using 2D-gel electrophoresis, MALDI-TOF and TOF/TOF. Presented at 58th American Society for Mass Spectrometry Conference, Salt Lake City, UT, May 22 - 27, 2010.

ORTIZ, P. A., M. E. BRUNO, T. MOORE, S. NESNOW, W. M. WINNIK, AND Y. GE. Proteomic Analysis of Propiconazole Responses in Mouse Liver-Comparison of Genomic and Proteomic Profiles . Presented at Experimental Biology meeting, Anaheim, CA, April 24 - 28, 2010.

GE, Y., M. E. BRUNO, K. WALLACE, W. M. WINNIK, AND S. NESNOW. Proteomic analyses of the environmental toxicity of carcinogenic chemicals. Presented at Society of Environmental Toxicology and Chemistry Annual Meeting (SETAC-EU), Seville, SPAIN, May 23 - 27, 2010.

ORTIZ, P. A., M. E. BRUNO, T. MOORE, S. NESNOW, W. M. WINNIK, AND Y. Ge. Proteomic analysis of propiconazole responses in mouse liver: comparison of genomic and proteomic profiles. Journal of Proteome Research . American Chemical Society, Washington, DC, 9(3):1268-1278, (2010).

NESNOW, S., J. W. ALLEN, C. F. BLACKMAN, P. CHEN, Y. GE, S. D. HESTER, L. C. KING, P. A. ORTIZ, J. A. ROSS, S. Y. THAI, W. O. WARD, W. M. WINNIK, AND D. C. WOLF. Application of Toxicogenomics to Develop a Mode of Action for a Carcinogenic Conazole Fungicide. Presented at NAS Symposium on Toxicity Pathway-Based Risk Assessment: Preparing for Paradigm Change, Washington, DC, May 11 - 13, 2009.

Chen, P., W. PADGETT, T. MOORE, W. M. WINNIK, G. LAMBERT, S. Y. THAI, S. D. HESTER, AND S. NESNOW. Three Conazoles Increase Hepatic Microsomal Retinoic Acid Metabolism and Decrease Mouse Hepatic Retinoic Acid Levels In Vivo. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 234:143 - 155, (2009).

MCCARROLL, N., E. REAVES, M. MANIBUSAN, D. C. WOLF, S. D. HESTER, J. W. ALLEN, S. Y. THAI, J. A. ROSS, Y. GE, W. M. WINNIK, L. C. KING, C. F. BLACKMAN, W. O. WARD, AND S. NESNOW. Use of Toxicogenomic Data at the US EPA to Inform the Cancer Asessment of the Fungicide Propiconazole. Presented at Symposium on Toxicity Pathway-Based Risk Assessment, Washington DC, DC, May 11 - 13, 2009.

MCCARROLL, N., E. REAVES, M. MANIBUSAN, D. C. WOLF, S. D. HESTER, J. W. ALLEN, S. Y. THAI, J. A. ROSS, Y. GE, W. M. WINNIK, L. C. KING, C. F. BLACKMAN, W. O. WARD, AND S. NESNOW. Use of toxicogenomic data by the US EPA Office of Pesticide Programs Cancer Assessment Reivew Committee. Presented at Society of Toxicology, Baltimore, MD, March 15 - 19, 2009.

NESNOW, S., W. PADGETT, G. B. NELSON, W. M. WINNIK, G. LAMBERT, M. H. GEORGE, AND J. A. ROSS. BENZO[A]PYRENE-7,8-QUINONE FORMS COVALENT-DNA ADDUCTS IN VITRO BUT NONE WERE DETECTED IN THE LUNGS OR LIVERS OF STRAIN A/J MICE IN VIVO. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.

CHEN, P., W. PADGETT, T. MOORE, W. M. WINNIK, S. Y. THAI, S. D. HESTER, AND S. NESNOW. CHARACTERIZATION OF CYPS IN THE METABOLISM OF ALL TRANS RETINOIC ACID BY LIVER MICROSOMES FROM MICE TREATED WITH CONAZOLES. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.

WINNIK, W. M. AND K. T. KITCHIN. MEASUREMENT OF OXIDATIVE STRESS PARAMETERS USING LIQUID CHROMATOGRAPHY - TANDEM MASS SPECTROSCOPY (LC-MS/MS). TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 223(1):100-106, (2008).

WINNIK, W. M. AND P. A. ORTIZ. PROTEOMIC ANALYSIS OPTIMIZATION: SELECTIVE PROTEIN SAMPLE ON-COLUMN RETENTION IN REVERSE-PHASE LIQUID CHROMATOGRAPHY. Journal of Chromatography B. Elsevier Science Ltd, New York, NY, 233(1):478-486, (2008).

ORTIZ, P. A., K. WALLACE, AND W. M. WINNIK. PROTEOMIC PROFILING OF CULTURED HUMAN BLADDER CELLS AFTER TRIVALENT ARSENIC EXPOSURES. Presented at Genetics and Environmental Mutagenesis Society (GEMS), Research Triangle Park, NC, October 06, 2008.

ORTIZ, P. A., K. WALLACE, AND W. M. WINNIK. PROTEOMIC PROFILING OF CULTURED HUMAN BLADDER CELLS AFTER TRIVALENT ARSENICAL EXPOSURES (SOT 2008). Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.

GE, Y., M. E. BRUNO, K. WALLACE, W. M. WINNIK, AND K. BAILEY. Proteomic Analysis of Arsenic-Induced Oxidative Stress in Human Epidermal Keratinocytes. Presented at 18th Society of Environmental Toxicology and Chemistry Europe Annual Meeting, Warsaw, POLAND, May 25 - 29, 2008.

WINNIK, W. M., J. CHILAKAPATI, K. WALLACE, K. T. KITCHIN, AND P. A. ORTIZ. Proteomic Profiling of Bladders from Mice Exposed with Sodium Arsenite. Presented at Environmental Mutagen Society 39th Annual Meeting, San Juan, PUERTO RICO, October 18 - 22, 2008.

ORTIZ, P. A., P. Chen, T. MOORE, S. NESNOW, AND W. M. WINNIK. Proteomic profiles of liver microsomes from mice treated with the hepatotumorigenic conazole, triadimefon . Presented at Experimental Biology 2008, San Diego, CA, April 05 - 09, 2008.

CHEN, P., W. PADGETT, T. MOORE, W. M. WINNIK, S. Y. THAI, S. D. HESTER, AND S. NESNOW. ALTERATIONS IN A11 TRANS RETINOIC ACID METABOLISM IN LIVER MICROSOMES FROM MICE TREATED WITH HEPATOTUMORIGENIC AND NON-HEPATOTUMORIGENIC CONAZOLES. Presented at North Carolina Society of Toxicology Fall Meeting - Metabolic Syndrome, Research Triangle Park, NC, October 12, 2007.

NESNOW, S., W. PADGETT, N. BALU, G. B. NELSON, W. M. WINNIK, G. LAMBERT, M. H. GEORGE, AND J. A. ROSS. BENZO[ A ]PYRENE-7,8-QUINONE FORMS COVALENT-DNA ADDUCTS IN VITRO BUT NONE WERE DETECTED IN THE LUNGS OR LIVERS OF STRAIN A/J MICE IN VIVO . Presented at 21st International Symposium for Polycyclic Aromatic Compounds (ISPAC), Trondheim, NORWAY, August 05 - 10, 2007.

SCOLLON, E., J. M. STARR, M. F. HUGHES, W. M. WINNIK, AND M. J. DEVITO. DETERMINATION OF PYRETHROID PESTICIDE RESIDUES FROM RAT TISSUE USING TWO-DIMENSIONAL LCMS. Presented at Meeting of the American Society of Mass Spectrometry, Indianapolis, IN, June 03 - 07, 2007.

CHEN, P., W. PADGETT, T. MOORE, S. D. HESTER, S. Y. THAI, W. M. WINNIK, AND S. NESNOW. DIFFERENTIAL EXPRESSION OF RETINOIC ACID BIOSYNTHETIC AND METABOLISM GENES IN LIVERS FROM MICE TREATED WITH HEPATOTUMORIGENIC AND NON-HEPATOTUMORIGENIC CONAZOLES. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

WINNIK, W. M. AND P. A. ORTIZ. ON-COLUMN ENRICHMENT OF HYDROPHOBIC CYP450 PROTEINS IN HPLC FRACTIONATION OF MOUSE MICROSOMES PRIOR TO PROTEIN DIGESTION AND NANOSPRAY-LC/MSMS ANALYSIS. Presented at 55th American Society for Mass Spectrometry Conference on Mass Spectrometry, Indianapolis, IN, June 03 - 07, 2007.

ORTIZ, P. A., K. WALLACE, AND W. M. WINNIK. PROTEOMIC PROFILING OF CULTURED HUMAN BLADDER CELLS AFTER TRIVALENT ARSENICAL EXPOSURES. Presented at Experimental Biology 2007, Washington, DC, April 28 - May 02, 2007.

GE, Y., M. E. BRUNO, P. A. ORTIZ, AND W. M. WINNIK. TOXICOPROTEOMICS AND ITS APPLICATION TO HUMAN HEALTH RISK ASSESSMENT. Presented at Human Proteome Organization (HUPO), 6th Annual World Congress, Seoul, SOUTH KOREA, October 06 - 10, 2007.

ORTIZ, P. A. AND W. M. WINNIK. APPLICATION OF PROTEOMIC METHODS TO ARSENIC EXPOSURE RESEARCH. Presented at ORD's Post Doc Face-to-Face Training and Meeting, Washington, DC, DC, May 15, 2006.