Science Inventory

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Bowers, E., S. McCullough, D. Morgan, L. Dailey, AND D. Diaz-Sanchez. Modeling mechanisms of susceptibility in vitro: Differential activation of the MAP kinase ERK, but not p38, mediates variability and adaptation in the pro-inflammatory response to ozone. Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Zavala-Mendez, J., R. Collins, L. Dailey, N. Hanley, A. Ledbetter, Todd Krantz, P. Evansky, S. McCullough, J. Harrill, AND M. Higuchi. Toxicity Screening of Volatile Chemicals Using a Novel Air-Liquid Interface In Vitro Exposure System. NC Society of Toxicology Fall Meeting, RTP, NC, October 30, 2017.

Ghio, Andy, J. Soukup, AND L. Dailey. Air pollution particles and iron homeostasis. Biochimica et Biophysica Acta. Elsevier Science Ltd, New York, NY, 1860(12):2816-25, (2016).

McCullough, Shaun D., E. Bowers, D. On, D. Morgan, Lisa A. Dailey, Ronald N. Hines, Robert B. Devlin, AND D. Diaz-Sanchez. Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 150(1):216-224, (2016).

Mirowsky, J., L. Dailey, AND R. Devlin. Differential Expression of pro-inflammatory and oxidative stress mediators induced by nitrogen dioxide and ozone in primary human bronchial epithelial cells. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 28(8):374-82, (2016).

Ghio, Andy, J. Soukup, L. Dailey, H. Tong, AND J. Richards. The biological effect of asbestos exposure is dependent on changes in iron homeostasis. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, 28(14):698-705, (2016).

Silbajoris, R., Bill Linak, O. Shenderova, C. Winterrowd, H. Chang, J. Zweier, A. Kota, L. Dailey, P. Bromberg, AND J. Samet. Detonation Nanodiamond Toxicity in Human Airway Epithelial Cells Is Modulated by Air Oxidation. Diamond and Related Materials. Elsevier B.V., Amsterdam, Netherlands, 58:16-23, (2015).

Ghio, Andy, J. Stonehuerner, J. Soukup, L. Dailey, M. Kesic, AND M. Cohen. Iron diminishes the in vitro biological effect of vanadium. Journal of Inorganic Biochemistry. Elsevier Science Ltd, New York, NY, 147:126-33, (2015).

Soukup, J., L. Dailey, AND Andy Ghio. Particle retention by respiratory epithelial cells is associated with persistent biological effect. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, 27(7):335-41, (2015).

Ghio, Andy, J. Soukup, L. Dailey, H. Tong, M. Kesic, G. Buddinger, AND G. Mutlu. Wood smoke particle sequesters cell iron to impact a biological effect. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 28(11):2104-11, (2015).

Ghio, Andy, S. Kummarapurugu, H. Tong, J. Soukup, L. Dailey, E. Boykin, Ian Gilmour, P. Ingram, V. Roggli, H. Goldstein, AND R. Reynolds. Biological effects of desert dust in respiratory epithelial cells and a murine model. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 26(5):299-305, (2014).

Duncan, K., Philip M. Cook, S. Gavett, L. Dailey, R. Mahoney, Andy Ghio, V. Roggli, AND R. Devlin. In vitro determinants of asbestos fiber toxicity: Effect on the relative toxicity of Libby Amphibole in pirmary human airway epithelial cells. Particle and Fibre Toxicology. BioMed Central Ltd, London, Uk, 11:2, (2014).

Ghio, Andy, J. Soukup, L. Dailey, J. Richards, K. Duncan, AND J. Lehmann. Iron decreases biological effects of ozone exposure. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 26(7):391-399, (2014).

McCullough, S., K. Duncan, S. Swanton, L. Dailey, D. Diaz-Sanchez, AND R. Devlin. Ozone Induces a Proinflammatory Response in Primary Human Bronchial Epithelial Cells Through Mitogen-Activated Protein Kinase Activation Without Nuclear Factor-kB Activation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. American Thoracic Society, New York, NY, 51(3):426-35, (2014).

Hatch, G., K. Duncan, D. Diaz-Sanchez, Mike Schmitt, Andy Ghio, Martha Sue Carraway, J. Mckee, L. Dailey, J. Berntsen, AND R. Devlin. Progress in Assessing Air Pollutant Risks from In Vitro Exposures: Matching Ozone Dose and Effect in Human Air Way Cells. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 141(1):198-205, (2014).

Silbajoris, R., L. Dailey, P. Wages, A. Speen, Steve Simmons, P. Bromberg, AND J. Samet. The ubiquitous PM component Zn2+ induces HO-1 expression through multiple targets in the Nrf2/Keap1 signaling pathway. Presented at American Thoracic Society, San Diego, CA, May 16 - 21, 2014.

Ghio, Andy, L. Dailey, J. Soukup, J. Stonehuerner, J. Richards, L. Brighton, A. Ross, AND R. Devlin. Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure. Particle and Fibre Toxicology. BioMed Central Ltd, London, Uk, 10(1):25, (2013).

Ghio, Andy, H. Tong, J. Soukup, L. Dailey, W. Cheng, J. Samet, M. Kesic, P. Bromberg, J. Turi, D. Upadhyay, S. Budinger, AND G. Mutlu. Sequestration of mitochondrial iron by silica particles initiates a biological effect. American Journal of Physiology - Lung Cellular and Molecular Physiology. American Physiological Society, Bethesda, MD, 305(10):L712-24, (2013).

GHIO, A. J., J. M. SOUKUP, L. A. DAILEY, J. Richards, J. TURI, E. N. Pavlisko, AND V. Roggli. Disruption of iron homeostasis in mesothelial cells following talc pleurodesis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. American Thoracic Society, New York, NY, 46(1):80-86, (2012).

JARDIM, M. J., L. A. DAILEY, AND D. DIAZ SANCHEZ. Distinct microRNA Expression in Human Airway Cells of Asthmatic Donors Identifies a Novel Asthma-associated Gene. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. American Thoracic Society, New York, NY, 47(4):536-42, (2012).

GHIO, A. J., J. M. SOUKUP, M. W. CASE, L. A. DAILEY, J. Richards, J. Bernsten, R. B. DEVLIN, S. Stone, AND A. RAPPOLD. Exposure to wood smoke particles produces an inflammation in healthy volunteers. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. BMJ / British Medical Journal Publishing Group, London, Uk, 69(3):170-5, (2012).

SOUKUP, J. M., A. J. GHIO, L. A. DAILEY, J. G. STONEHUERNER, J. H. Richards, M. Brighton, A. J. Rose, AND R. B. DEVLIN. Growth of airway epithelial cells at an air-liquid interface changes both the response to particle exposure and iron homeostasis. Presented at American Thoracic Society (ATS) Annual meeting, San Francisco, CA, May 18 - 23, 2012.

Schäuble, C., R. Hampel, B. Susanne, R. Rückerl, R. Phipps, D. Diaz-Sanchez, R. Devlin, Jackie Carter, J. Soukup, R. Silbajoris, L. Dailey, W. Koenig, J. Cyrys, U. Geruschkat, P. Belcredi, U. Kraus, A. Peters, AND A. Schneider. Short-term Effects of Air Temperature on Blood Markers of Coagulation and Inflammation in Potentially Susceptible Individuals. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. BMJ / British Medical Journal Publishing Group, London, Uk, 69(9):670-8, (2012).

SOUKUP, J. M., L. A. DAILEY, AND A. J. GHIO. Activation of respiratory epithelial cells by wood smoke particles persists beyond immediate exposure. Presented at American Thoracic Society (ATS) Meeting, Denver, CO, May 13 - 18, 2011.

SILBAJORIS, R. A., J. M. SAMET, L. A. DAILEY, S. SIMMONS, P. A. Bromberg, AND W. Reed. Ambient particulate matter induces IL-8 expression through an alternative NF-kB mechanism in human airway epithelial cells. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(10):1379-83, (2011).