Science Inventory

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Denny, J., Joe Korte, C. Knutsen, J. Olker, S. Degitz, M. Hornung, P. Hartig, AND M. Cardon. Screening the ToxCast Phase I Chemical Library for inhibition of Deiodinase Type I enzyme activity. SETAC Midwest Chapter, Minneapolis, MN, July 20 - 22, 2017.

Denny, J., Joe Korte, C. Knutsen, J. Olker, J. Christensen, P. Kent, P. Hartig, M. Cardon, S. Degitz, AND M. Hornung. Screening the ToxCast Phase I, II, and e1K Chemical Libraries for Inhibition of Deiodinase Type 1,2 and 3 Enzyme Activity. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Haselman, J., M. Sakurai, N. Watanabe, Y. Goto, Y. Onishi, Y. Ito, Y. Onoda, Pat Kosian, Joe Korte, R. Johnson, T. Iguchi, AND S. Degitz. Development of the larval amphibian growth and development assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 36(12):1651-1661, (2016).

Haselman, J., Pat Kosian, Joe Korte, A. Olmstead, T. Iguchi, R. Johnson, AND S. Degitz. Development of the larval amphibian growth and development assay: Effects of chronic 4-tert-octylphenol or 17ß-trenbolone exposure in Xenopus laevis from embryo to juvenile. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 36(12):1639-1650, (2016).

Kosian, Pat, Joe Korte, J. Haselman, M. Hornung, M. Hotchkiss, AND M. Gilbert. Analysis of thyroid hormones in gland and serum using liquid chromatography-tandem mass spectrometry. MWSETAC/SOT Meeting, Duluth, MN, March 09 - 11, 2015.

Hornung, M., Pat Kosian, J. Haselman, Joe Korte, K. Challis, C. Macherla, E. Nevalainen, AND S. Degitz. In vitro, ex vivo, and in vivo determination of thyroid hormone modulating activity of benzothiazoles. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 146(2):254-264, (2015).

Haselman, J., Pat Kosian, Joe Korte, A. Olmstead, R. Johnson, AND S. Degitz. Xenopus laevis Müllerian ducts are sensitive indicators of estrogenic or androgenic chemical exposure in vivo. Society of Toxicology, San Diego, CA, March 22 - 26, 2015.

Haselman, J., Pat Kosian, Joe Korte, A. Olmstead, R. Johnson, AND S. Degitz. Xenopus laevis Müllerian ducts are sensitive indicators of estrogenic or androgenic chemical exposure in vivo (poster presentation). MWSETAC/SOT Meeting, Duluth, MN, March 09 - 11, 2015.

Nichols, J., M. Hornung, Joe Korte, J. Haselman, Joe Tietge, AND S. Degitz. A quantitative adverse outcome pathway model for thyroid axis disruption in Xenopus laevis tadpoles. SETAC North America, Vancouver, BC, CANADA, November 09 - 13, 2014.

Hornung, M., J. Haselman, Joe Korte, Pat Kosian, K. Challis, S. Hall, AND S. Degitz. Comparison of in vitro and ex vivo thyroid hormone synthesis inhibition results and in vivo outcomes for a series of benzothiazoles. Presented at Society of Toxicology, Phoenix, AZ, March 24 - 27, 2014.

Johnson, R., S. Degitz, K. Flynn, D. Lothenbach, D. Hammermeister, F. Whiteman, Joe Korte, J. Haselman, AND Pat Kosian. EDSP Tier 2 test (T2T) guidances and protocols are delivered, including web-based guidance for diagnosing and scoring, and evaluating EDC-induced pathology in fish and amphibian. U.S. Environmental Protection Agency, Washington, DC, 2014.

Eid, E., Joe Korte, Pat Kosian, L. Dahlin, J. Haselman, S. Hall, AND S. Degitz. Use of a 48 hour static renewal assay for evaluating UGT gene induction in X. tropicalis. Presented at Society of Environmental Toxicology and Chemistry, March 19 - 20, 2013.

TIETGE, J. E., S. J. DEGITZ, J. HASELMAN, B. C. BUTTERWORTH, J. J. KORTE, P. A. KOSIAN, A. LINDBERG-LIVINGSTON, E. M. BURGESS, P. BLACKSHEAR, AND M. HORNUNG. Inhibition of the Thyroid Hormone Pathway in Xenopus laevis by 2-mercaptobenzothiazole. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 126:128-136, (2012).

OLMSTEAD, A. W., P. A. KOSIAN, R. D. JOHNSON, P. BLACKSHEAR, J. HASELMAN, C. BLANKSMA, J. J. KORTE, G. W. HOLCOMBE, E. BURGESS, A. LINDBERG-LIVINGSTON, B. BENNETT, K. K. WOODIS, AND S. J. DEGITZ. Trenbolone causes mortality and altered sexual differentiation in Xenopus topicalis during larval development . ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 31(10):2391-2398, (2012).

HORNUNG, M. W., S. J. DEGITZ, J. E. TIETGE, J. J. KORTE, J. HASELMAN, P. A. KOSIAN, A. J. LINDBERG-LIVINGSTON, AND E. M. BURGESS. A Pathway Approach to Predicting Thyroid Hormone Disrupting Activity of Chemicals Using in vitro, ex vivo and in vivo Assays. Presented at International Symposium on Amphibian Endocrinology and Neurobiology, Ann Arbor, MI, July 11 - 13, 2011.

OLMSTEAD, A. W., L. S. BLAKE, P. A. KOSIAN, J. HASELMAN, J. J. KORTE, R. D. JOHNSON, C. BLANKSMA, K. LILLEGARD, S. ZAVODNIK, B. HEGGESTAD, AND S. J. DEGITZ. Assessment of the Endocrine Toxicity of the Fungicide Prochloraz using the Larval Amphibian Growth and Development Assay. Presented at Society of Environmental Toxicology and Chemistry, Boston, MA, November 13 - 17, 2011.

STERNBERG, R., K. R. THOEMKE, J. J. KORTE, S. M. MOEN, J. OLSON, L. KORTE, J. E. TIETGE, AND S. J. DEGITZ. Control of Pituitary Thyroid-stimulating Hormone Synthesis and Secretion by Thyroid Hormones during Xenopus Metamorphosis. GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 173(3):428-437, (2011).

PORTER, K. L., A. W. OLMSTEAD, D. M. KUMSHER, D. M. KUMSHER, W. E. DENNIS, R. L. SPRADO, G. W. HOLCOMBE, J. J. KORTE, A. LINDBERG-LIVINGSTON, AND S. J. DEGITZ. Effects of 4-tert-octylphenol on Xenopus tropicalis in a Long Term Exposure. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 103(3-4):159-169, (2011).

KORTE, J. J., R. M. STERNBERG, J. A. SERRANO, K. R. THOEMKE, S. M. MOEN, K. E. LILLEGARD, M. W. HORNUNG, J. E. TIETGE, AND S. J. DEGITZ. Thyroid-stimulating Hormone (TSH): Measurement of Intracellular, Secreted, and Circulating Hormone in Xenopus laevis and Xenopus tropicalis. GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 171(3):319-325, (2011).

CONNORS, K., J. J. KORTE, G. ANDERSON, AND S. J. DEGITZ. Characterization of Thyroid Hormone Transporter Protein Expression during Tissue-specific Metamorphic Events in Xenopus tropicalis . GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 168(1):149-159, (2010).

TIETGE, J. E., B. C. BUTTERWORTH, J. HASELMAN, G. W. HOLCOMBE, M. HORNUNG, J. J. KORTE, P. A. KOSIAN, S. J. DEGITZ, AND M. WOLFE. Early Temporal Effects of Three Thyroid Hormone Synthesis Inhibitors in Xenopus laevis. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 98(1):44-50, (2010).

OLMSTEAD, A. W., P. A. KOSIAN, L. BLAKE, J. HASELMAN, J. J. KORTE, G. W. HOLCOMBE, AND S. J. DEGITZ. Endocrine Toxicity of Trenbolone in the Western Clawed Frog, Xenopus (Silurana) tropicalis. Presented at SETAC North America 31st Annual Meeting, Portland, OR, November 07 - 11, 2010.

SERRANO, J. A., L. HIGGINS, B. A. WITTHUHN, L. B. ANDERSON, G. W. HOLCOMBE, P. A. KOSIAN, J. J. KORTE, J. E. TIETGE, AND S. J. DEGITZ. In vivo Assessment and Potential Diagnosis of Xenobiotics that Perturb the Thyroid Pathway: Proteomic Analysis of Xenopus laevis Brain Tissue following Exposure to Model T4 Inhibitors. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART D: GENOMICS AND PROTEOMICS. Elsevier BV, AMSTERDAM, Netherlands, 5(2):138-150, (2010).

TIETGE, J. E., S. J. DEGITZ, J. T. HASELMAN, J. J. KORTE, P. A. KOSIAN, A. J. LINDBERG-LIVINGSTON, E. M. BURGESS, AND M. W. HORNUNG. Inhibition of the Thyroid Hormone Pathway in Xenopus by Mercaptobenzothiazole. Presented at SETAC North America 31st Annual Meeting, Portland, OR, November 07 - 11, 2010.

STERNBERG, R. M., K. R. THOEMKE, J. J. KORTE, S. M. MOEN, J. E. TIETGE, AND S. J. DEGITZ. Negative Feedback Control of Pituitary Thyroid-stimulating Hormone Synthesis and Secretion by Thyroid Hormones during Metamorphosis in Xenopus laevis. Presented at 30th Annual Meeting of SETAC North America, New Orleans, LA, November 19 - 23, 2009.