Science Inventory

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PRESSMAN, J. G., S. D. RICHARDSON, T. F. SPETH, R. J. MILTNER, M. G. NAROTSKY, E. S. HUNTER, G. E. RICE, L. K. TEUSCHLER, T. A. MCDONALD, S. Parvez, S. W. Krasner, H. S. Weinberg, A. B. McKague, AND J. E. SIMMONS. Concentration, Chlorination, and Chemical Analysis of Drinking Water for Disinfection Byproduct Mixtures Health Effects Research: U.S. EPA’s Four Lab Study . ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(19):7184-7192, (2010).

NICHOLS, H. P., S. C. JEFFAY, M. BARRIER, M. G. NAROTSKY, J. Simmons, AND E. S. HUNTER. Effects Of Haloacetic Acid Mixtures in a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) Assay. Presented at Society of Toxicology Meeting, Salt Lake City, UT, March 07 - 11, 2010.

JEFFAY, S. C., H. P. NICHOLS, M. BARRIER, AND E. S. HUNTER. Effects Of Haloacetic Acids and their major metabolites in a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) Assay. Presented at Society of Toxicology Meeting, Salt Lake City, UT, March 07 - 11, 2010.

BARRIER, M., S. C. JEFFAY, H. P. NICHOLS, K. J. CHANDLER, M. Hoopes, AND E. S. HUNTER. Evaluation of a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) assay (Keystone Sym). Presented at Keystone Symposium on Stem Cell Differentiation and Dedifferentiation, Keystone, CO, February 15 - 20, 2010.

BARRIER, M., S. C. JEFFAY, H. P. NICHOLS, M. L. HOOPES, AND E. S. HUNTER. Evaluation of a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) assay (SOT). Presented at Society of Toxicology 49th Annual meeting, Salt Lake City, UT, March 07 - 11, 2010.

CHANDLER, K. J., E. S. HUNTER, S. C. JEFFAY, H. P. NICHOLS, M. Hoopes, M. BARRIER, J. Habig, AND T. B. KNUDSEN. High-throughput Screening of ToxCast" Phase I Chemicals in an Embryonic Stem Cell Assay Reveals Potential Disruption of a Critical Developmental Signaling Pathway. Presented at Teratology, Louisville, KY, June 26 - 30, 2010.

HUNTER, E. S., H. P. NICHOLS, S. C. JEFFAY, M. L. HOOPES, AND M. BARRIER. Screening ToxCast™ Phase I Chemicals in a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) Assay. Presented at Society of Toxicology 49th Annual meeting, Salt Lake City, UT, March 07 - 11, 2010.

BARRIER, M., S. C. JEFFAY, H. P. NICHOLS, K. SLENTZ-KESLER, AND E. S. HUNTER. Development of an invitro technique to use mouse embryonic stem cell in evaluating effects of xenobiotics. Presented at NC Society of Toxicology, RTP, NC, February 26, 2009.

RICHARDSON, S. D., J. E. SIMMONS, M. G. NAROTSKY, L. D. CLAXTON, E. S. HUNTER, R. J. MILTNER, J. G. PRESSMAN, T. F. SPETH, G. E. RICE, L. K. TEUSCHLER, S. W. Krasner, AND H. S. Weinberg. Meeting in San Francisco: Integrated Disinfection By-Products Mixtures Research: Results from the Four Lab Study. Presented at Micropol and Ecohazard 2009 Conference, San Francisco, CA, June 08 - 10, 2009.

HUNTER, E. S., S. J. PADILLA, M. BARRIER, K. J. CHANDLER, AND T. B. KNUDSEN. Predictive Modeling of Developmental and Reproductive Toxicity Pathways. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.

NAROTSKY, M. G., E. S. HUNTER, J. G. PRESSMAN, R. J. MILTNER, T. F. SPETH, S. D. RICHARDSON, L. K. TEUSCHLER, G. E. RICE, G. R. KLINEFELTER, J. M. GOLDMAN, L. F. STRADER, R. W. LUEBKE, V. C. MOSER, J. Chen, G. C. Douglas, B. L. LASLEY, AND J. E. SIMMONS. The Four Lab Study: Assessment of Reproductive Toxicity of Drinking Water Concentrates in a Multi-Generational Rat Bioassay and Human Placental Cell Cultures. Presented at OW/ORD Seminar Series, Washington, DC, May 13, 2009.

EDWARDS, S. W., J. PRESTON, A. GELLER, A. M. JARABEK, D. C. WOLF, E. A. COHEN-HUBAL, G. T. ANKLEY, H. A. EL-MASRI, I. A. SHAH, J. R. FOWLE, J. A. ROSS, J. W. NICHOLS, K. M. CROFTON, M. J. DEVITO, T. V. RAMABHADRAN, R. J. KAVLOCK, E. S. HUNTER, T. B. KNUDSEN, AND W. R. MUNDY. Toxicity pathway-based mode of action modeling for risk assessment. Presented at Symposium on toxicity pathway-based risk assessment, washington dc, DC, May 11 - 13, 2009.

PRESSMAN, J. G., R. J. MILTNER, T. F. SPETH, S. D. RICHARDSON, M. G. NAROTSKY, E. S. HUNTER, J. E. SIMMONS, G. E. RICE, AND L. K. TEUSCHLER. U.S. EPA’s Four Lab Study: Integrated Assessment of Complex Disinfection Byproduct Mixtures - Abstract. Presented at American Water Works Association Annual Conference and Exposition, San Diego, CA, June 14 - 18, 2009.

PRESSMAN, J. G., R. J. MILTNER, T. F. SPETH, S. D. RICHARDSON, M. G. NAROTSKY, E. S. HUNTER, J. E. SIMMONS, G. E. RICE, AND L. K. TEUSCHLER. U.S. EPA’s Four Lab Study: Integrated Assessment of Complex Disinfection Byproduct Mixtures - Slides. Presented at American Water Works Association Annual Conference and Exposition, San Diego, CA, June 14 - 18, 2009.

NAROTSKY, M. G., E. S. HUNTER, G. R. KLINEFELTER, J. M. GOLDMAN, L. F. STRADER, J. G. PRESSMAN, R. J. MILTNER, T. F. SPETH, S. D. RICHARDSON, L. K. TEUSCHLER, G. E. RICE, AND J. E. SIMMONS. Assessment of Reproductive Effects of Complex Mixtures of Disinfection By-Products in a Multi-Generational Rat Bioassay of Drinking Water Concentrates - Monterey. Presented at Annual Meeting of the TERATOLOGY SOCIETY, MONTEREY, CA, June 28 - July 02, 2008.

NAROTSKY, M. G., E. S. HUNTER, G. R. KLINEFELTER, J. M. GOLDMAN, L. F. STRADER, J. G. PRESSMAN, R. J. MILTNER, T. F. SPETH, S. D. RICHARDSON, L. K. TEUSCHLER, G. E. RICE, AND J. E. SIMMONS. Assessment of reproductive effects on complex mixtures of disinfection by-products in a multigenerational rat bioassay of drinking water concentrates. Presented at Teratology, Monterey, CA, June 28 - July 02, 2008.

PRESSMAN, J. G., T. F. SPETH, R. J. MILTNER, M. G. NAROTSKY, E. S. HUNTER, S. D. RICHARDSON, L. K. TEUSCHLER, G. E. RICE, AND J. E. SIMMONS. CONCENTRATION AND TREATMENT OF DRINKING WATERS IN THE FOUR LAB STUDY. Presented at Toxicology and Risk Assessment Conference, Cincinnati, OH, April 15, 2008.

RICHARDSON, S. D., J. E. SIMMONS, M. G. NAROTSKY, L. D. CLAXTON, E. S. HUNTER, R. J. MILTNER, J. G. PRESSMAN, T. F. SPETH, G. E. RICE, L. K. TEUSCHLER, S. W. Krasner, AND H. S. Weinberg. Integrated Disinfection By-Products Mixtures Research: Results from the Four Lab Study. Presented at 56th ASMS Conference on Mass Spectrometry, Denver, CO, June 01 - 05, 2008.

RICE, G. E., L. K. TEUSCHLER, T. F. SPETH, S. D. RICHARDSON, R. J. MILTNER, K. M. SCHENCK, C. Gennings, E. S. HUNTER, M. G. NAROTSKY, AND J. E. SIMMONS. Integrated Disinfection By-Products Research: Assessing Reproductive and Developmental Risks Posed by Complex Disinfection By-Product Mixtures . JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 71(17):1222-1234, (2008).

Narotsky, M. G., E. S. Hunter, J. G. Pressman, R. J. Mitner, T. F. Speth, S. D. Richardson, L. K. Teuschler, G. E. Rice, AND J. E. Simmons. Pregnancy Outcome in a Multi-Generational Rat Bioassay of Drinking Water Concentrates in the Four Lab Study. Presented at Toxicoloy and Risk Assessment, West Chester, OH, April 14 - 17, 2008.

SIMMONS, J. E., S. D. RICHARDSON, L. K. Teuscher, R. J. MILTNER, T. F. SPETH, K. M. SCHENCK, E. S. HUNTER, AND G. E. RICE. Research Issues Underlying the Four-Lab Study: Integrated Disinfection Byproducts Mixtures Research. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 71(17):1125-1132, (2008).

SIMMONS, J. E., S. D. RICHARDSON, L. K. TEUSCHLER, G. E. RICE, T. F. SPETH, R. J. MILTNER, J. G. PRESSMAN, M. G. NAROTSKY, AND E. S. HUNTER. The Integrated Disinfection By-Product Mixtures Project (“4-Lab Study”): An Overview. Presented at Toxicology and Risk Assessment Conference, Cincinnati, OH, April 14 - 18, 2008.

SIMMONS, J. E., S. D. RICHARDSON, G. E. RICE, T. F. SPETH, R. J. MILTNER, E. S. HUNTER, M. G. NAROTSKY, K. M. SCHENCK, L. D. CLAXTON, R. A. PEGRAM, T. A. MCDONALD, D. S. BEST, S. H. WARREN, A. B. DEANGELO, W. O. WARD, J. G. PRESSMAN, AND L. K. TEUSCHLER. The Power of Four (the 4-Lab Study): ORD’s Integrated Disinfection By-Products Mixtures Research Project. Presented at Office of Solid Waste Science Seminar, Washington, DC, September 09 - 12, 2008.

BARRIER, M., S. C. JEFFAY, H. P. NICHOLS, K. SLENTZ-KESLER, AND E. S. HUNTER. Using the mouse embryonic stem cell test (EST) to evaluate the embryotoxicity of haloacetic acids. Presented at International Society for Stem Cell Research, Philadelphia, PA, June 11 - 14, 2008.

NAROTSKY, M. G., J. G. PRESSMAN, R. J. MILTNER, T. F. SPETH, L. K. TEUSCHLER, G. E. RICE, S. D. RICHARDSON, D. S. BEST, T. A. MCDONALD, E. S. HUNTER, AND J. E. SIMMONS. GESTATIONAL AND LACTATIONAL EFFECTS IN RATS OF SODIUM, SULFATE, AND CONCENTRATED DISINFECTION BY-PRODUCTS IN DRINKING WATER. Presented at 47th Annual Meeting of the Teratology Society, Pittsburgh, PA, June 23 - 28, 2007.