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Records 51 to
75
of 118 records from author Marina Evans
2007
YOKLEY, K. AND M. V. EVANS. AN EXAMPLE OF MODEL STRUCTURE DIFFERENCES USING SENSITIVITY ANALYSES IN PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS OF TRICHLOROETHYLENE IN HUMANS. BULLETIN OF MATHEMATICAL BIOLOGY. Elsevier Science Ltd, New York, NY, 69(8):2591-625, (2007).
YOKLEY, K., M. V. EVANS, AND J. E. SIMMONS. ESTABLISHING CHANGES IN METABOLISM OF CARBON TETRACHLORIDE IN THE PRESENCE OF TRICHLOROETHYLENE IN THE RAT THROUGH THE USE OF PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELING. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.
EVANS, M. V., H. M. YANG, T. A. MCDONALD, Y. M. SEY, AND J. E. SIMMONS. PHYSIOLOGICALLY BASED PHARMACOKINEITC (PBPK) MODELING OF METABOLIC INHIBITION FOR INTERACTION BETWEEN TRICHLOROETHYLENE AND CHLOROFORM. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.
2006
BLANCATO, J. N., M. V. EVANS, A. TSANG, AND FRED W. POWER. A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR METHYL TERTIARY BUTYL ETHER (MTBE): A REVIEW OF EXISTING MODELS. Presented at 2006 Annual Society of Toxicology, San Diego, CA, March 05 - 09, 2006.
CALDWELL, J. C., M. V. EVANS, A. MARCUS, C. S. SCOTT, W. CHIU, M. S. OKINO, AND P. W. PREUSS. Applying Mode-Of-Action And Pharmacokinetic Considerations In The Contempary Cancer Risk Assessments: An Example With Trichloroethylene (Clewell And Andersen, 2004). CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, 36(3):291-294, (2006).
DEVITO, M. J., M. V. EVANS, M. S. OKINO, B. R. SONAWANE, CHADWICK M. THOMPSON, L. S. BIRNBAUM, K. YOKLEY, C. CORTON, J. LEE, AND A. M. GELLER. EVALUATION OF ALTERED SENSITIVITY OF OLDER ADULTS TO ENVIRONMENTAL AGENTS USING PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELING. Presented at U.S. EPA 2006 Science Forum, Washington, DC, May 16 - 18, 2006.
KENYON, E. M., M. F. HUGHES, C. R. EKLUND, AND M. V. EVANS. EVALUATION OF INTERSPECIES DIFFERENCES IN PHARMACOKINETICS (PK) USING A PBPK MODEL FOR THE PESTICIDE DIMETHYLARSINIC ACID (DMAV) . Presented at 45th Annual Society of Toxicology Meeting 2006, San Diego, CA, March 05 - 09, 2006.
YOKLEY, K. AND M. V. EVANS. MODEL DEVELOPMENT AND EVALUATION FOR TRICHLOROETHYLENE METABOLISM IN HUMANS. Presented at SIAM Annual Meeting, Boston, MA, July 11 - 12, 2006.
POWER, FRED W., J. N. BLANCATO, M. V. EVANS, A. TSANG, AND J. C. CALDWELL. PHYSIOLOGICALLY-BASED PHARMACOKINETIC ( PBPK ) MODEL FOR METHYL TERTIARY BUTYL ETHER ( MTBE ): A REVIEW OF EXISTING MODELS. Presented at Society of Toxicology, San Diego, CA, March 05 - 09, 2006.
EKLUND, C. R., W. K. BOYES, J. E. SIMMONS, AND M. V. EVANS. THE EFFECT OF UNCERTAINTY FACTOR PLACEMENT IN A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL OF TRICHLOROETHYLENE (TCE) FOR ACUTE EXPOSURE GUIDELINE LEVELS (AEGL). . Presented at 45th Annual Society of Toxicology Meeting 2006, San Diego, CA, March 05 - 09, 2006.
2005
Kenyon, E M., M F. Hughes, C R. Eklund, AND M V. Evans. A PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR THE PESTICIDE MONOMETHYLARSONIC ACID (MMA). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
Evans, M V., R. TORNERO-VELEZ, M J. DeVito, M S. Okino, A M. Geller, J N. Blancato, AND L S. Birnbaum. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMOKINETICS (PBPK) MODEL TO COMPARE DIFFERENCES IN DISPOSITION OF TRICHLOROETHYLENE (TCE) IN ADULT VERSUS ELDERLY RATS. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
Boyes, W K., M. V. EVANS, C EKLUND, P. Janssen, AND J E. Simmons. DURATION ADJUSTMENT OF ACTUE EXPOSURE GUIDELINE LEVEL (AEGL) VALUES FOR TRICHLOROETHYLENE (TCE) USING A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL. RISK ANALYSIS 25(3):677-686, (2005).
OKINO, M. S., M. V. EVANS, S. ISUKAPALLI, S. WANG, P. G. GEORGOPOULOS, M. KARSTADT, R. TORNERO-VELEZ, M. DEVITO, L. S. BIRNBAUM, J. N. BLANCATO, AND A. M. GELLER. EVALUATING RISK IN OLDER ADULTS USING PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS. Presented at EPA Science Forum 2005, Washington, DC, May 16 - 18, 2005.
Granville, C. A., M. K. Ross, R TORNERO-VELEZ, N. M. Hanley, A. Gold, A M. Richard, K. Funasaka, A H. Tennant, A D. Kligerman, M V. Evans, AND D M. Demarini. GENOTOXICITY AND METABOLISM OF THE SOURCE-WATER CONTAMINANT 1,1-DICHLOROPROPENE: ACTIVATION BY GSTT1-1 AND STRUCTURE-ACTIVITY CONSIDERATIONS. MUTATION RESEARCH. Elsevier Science BV, Amsterdam, Netherlands, 572(1-2):98-112, (2005).
BOYES, W. K., M. S. BERCEGEAY, TODD T. KRANTZ, M. V. EVANS, V. A. BENIGNUS, AND J. E. SIMMONS. MOMENTARY BRAIN CONCENTRATION OF TRICHLOROETHYLENE PREDICTS THE EFFECTS ON RAT VISUAL FUNCTION. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 87(1):187-196, (2005).
Simmons, J E., M V. Evans, AND W K. Boyes. MOVING FROM EXTERNAL EXPOSURE CONCENTRATION TO INTERNAL DOSE: DURATION EXTRAPOLATION BASED ON PHYSIOLOGICALLY-BASED PHARACOKINETIC-MODEL DERIVED ESTIMATES OF INTERNAL DOSE. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 68(11-12):927-950, (2005).
Bushnell, P J., T E. Samsam, W M. Oshiro, C R. Eklund, AND M V. Evans. ROUTE-DEPENDENT EFFECTS OF TOLUENE ON SIGNAL DETECTION BEHAVIOR IN RATS. Presented at Society of Toxicology, New Orleans, LA, March 06 - 10, 2005.
OKINO, M. S., W. CHIU, M. V. EVANS, F. W. POWER, J. C. LIPSCOMB, R. TORNERO-VELEZ, C. C. DARY, J. N. BLANCATO, C. CHEN, AND L. S. BIRNBAUM. SUITABILITY OF USING IN VITRO AND COMPUTATIONALLY ESTIMATED PARAMETERS IN SIMPLIFIED PHARMACOKINETIC MODELS. Presented at North American ISSX Meeting , Maui, HI, October 23 - 27, 2005.
2004
Evans, M V., F W. Power, C C. Dary, R. TORNERO-VELEZ, AND J. Blancato. APPLICATION OF THE EXPOSURE DOSE ESTIMATING MODEL (ERDEM) TO ASSESSMENT OF DERMAL EXPOSURE IN THE RAT TO MALATHION. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
Ruiz, A., A. Tsang, F W. Power, J. Licitra, J N. Blancato, C C. Dary, AND M V. Evans. COMPREHENSIVE PBPK MODELING APPROACH USING THE EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM). Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
Himmelstein, M., S. C. Carpenter, M V. Evans, Hinderliter,PM, AND E M. Kenyon. KINETIC MODELING OF B-CHLOROPRENE METABOLISM:II. THE APPLICATION OF PHYSIOLOGICALLY BASED MODELLING FOR CANCER DOSE RESPONSE ANALYSIS. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 79(1):28-37, (2004).
TORNERO-VELEZ, R., M. K. Ross, C. A. Granville, J. Laskey, J. P. Jones, D M. DeMarini, AND M V. Evans. METABOLISM AND MUTAGENICITY OF SOURCE WATER CONTAMINANTS 1, 3-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE. DRUG METABOLISM AND DISPOSITION 32(1):123-131, (2003).
Ross, M. K., R TORNERO-VELEZ, C. Granville, A. Gold, M V. Evans, AND D M. DeMarini. METABOLISM OF 1,1- AND 1,3- DICHLOROPROPENE: A MECHANISM OF BIOACTIVATION BY GLUTATHIONE. Presented at International Society for the Study of Xenobiotics, Vancouver, Canada, August 29-September 2, 2004.
Simmons, J E., M V. Evans, AND W K. Boyes. MOVING FROM EXTERNAL EXPOSURE CONCENTRATION TO INTERNAL DOSE: DURATION EXTRAPOLATION BASED ON PHYSIOLOGICALLY-BASED PHARMACOKINETIC-MODEL DERIVED ESTIMATES OF INTERNAL DOSE. Presented at DOD Risk Assessment Conference, Dayton, OH, April 26-30, 2004.