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Records 26 to 50 of 61 records from author Leah Wehmas

2022
MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. American Society for Mass Spectrometry Conference, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19908283
MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. SETAC NTA, Durham, NC, May 22 - 26, 2022. https://doi.org/10.23645/epacomptox.19758634
Wehmas, L., C. Wood, P. Guan, M. Gosink, AND S. Hester. Organocatalyst treatment improves variant calling and mutant detection in archival clinical samples. Scientific Data. Springer Nature, New York, NY, 12:6509, (2022). https://doi.org/10.1038/s41598-022-10301-0
2021
Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal Dose of Selected PFAS (Perfluoro-3-methoxypropanoic acid and) in Rat Plasma from Short Term Dosing Studies. 69th Annual American Society for Mass Spectrometry (ASMS) Conference, Philadelphia, Pennsylvania, October 31 - November 04, 2021. https://doi.org/10.23645/epacomptox.16814986
Wehmas, L., T. Tal, M. Russo, D. Gorelick, AND L. Zhang. Pairing adverse outcome pathway discovery with advances in gene editing to solve toxicity mechanisms (SOT 2021). Society of Toxicology 2021 Symposium, Orlando, FL, March 12 - 26, 2021.
2020
Pettit, S., K. Jerome, D. Rouquié, B. Mari, P. Barbry, Y. Kanda, M. Matsumoto, S. Hester, L. Wehmas, J. Botten, AND E. Bruce. 'All In': a pragmatic framework for COVID-19 testing and action on a global scale. EMBO Molecular Medicine. EMBO Press, Heidelberg, Germany, 12(6):e12634, (2020). https://doi.org/10.15252/emmm.202012634
Wehmas, L., S. Hester, AND C. Wood. Direct Formalin Fixation Induces Widespread Transcriptomic Effects in Archival Tissue Samples. Scientific Reports. Nature Publishing Group, London, Uk, 10:14497, (2020). https://doi.org/10.1038/s41598-020-71521-w
Malloy, M., G. Carswell, B. Bennet, P. Bushel, L. Wehmas, S. Hester, AND B. Chorley. Establishing methods to assess epigenetic signatures in archived study tissues. 2020 SOT Annual Meeting, Research Triangle Park, NC, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.14340239
Howey, X., T. Tal, S. Gaballah, C. Wood, L. Bertotto, AND L. Wehmas. Identifying key events that drive neurotoxicity in larval zebrafish with transcriptomic concentration response modeling. Presented at Developmental Neurotoxicity Journal Club Meeting, RTP, NC, April 08, 2020. https://doi.org/10.23645/epacomptox.19172375
Wehmas, L. The state of CRISPR-Cas9 gene editing technology and applications for toxicology research (SOT 2021). Society of Toxicology 2021 Annual Meeting (Symposium), Virtual, Florida, March 12 - 26, 2020. https://doi.org/10.23645/epacomptox.14466048
Cannizzo, M., S. Hester, L. Wehmas, K. Bailey, D. Cowie, AND R. Currie. Transcriptional profiling informs target organ phenotypic responses of agrochemicals in rats. Genetics and Environmental Mutagenesis Society (GEMS) Spring 2020 Virtual Symposium, Virtual, North Carolina, May 12, 2020. https://doi.org/10.23645/epacomptox.12505454
Cannizzo, M., L. Wehmas, K. Bailey, D. Cowie, R. Currie, AND S. Hester. Transcriptional profiling informs target organ phenotypic responses of agrochemicals in rats (SOT 2020). 59th Annual Society of Toxicology (SOT) meeting, Anaheim, CA, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.12933878
2019
Wehmas, L., C. Wood, B. Chorley, C. Yauk, G. Nelson, AND S. Hester. Enhanced Quality Metrics for Assessing RNA Derived From Archival Formalin-Fixed Paraffin-Embedded Tissue Samples. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 170(2):357-373, (2019). https://doi.org/10.1093/toxsci/kfz113
Catron, T., A. Swank, L. Wehmas, D. Phelps, J. McCord, R. Singh, J. Sobus, S. Keely, N. Brinkman, C. Wood, M. Strynar, AND T. Tal. Estradiol exposure disrupts the microbiota-gut-brain axis during zebrafish development. Society of Toxicology, Baltimore, Maryland, March 10 - 14, 2019.
2018
Wehmas, L., C. Wood, AND S. Hester. Characterizing Genomic Effects of Formalin Fixation in Archival Samples. North Carolina Biotechnology Center, RTP, North Carolina, July 11 - 12, 2018.
Carswell, G., L. Wehmas, S. Hester, B. Vallanat, J. Chamberlin, C. Wood, B. Chorley, AND B. Bennett. DNA Methylation Alterations Associated with Latent Carcinogenic Activity of Dichloroacetic Acid in Mice. DNA and RNA Methylation - Keystone Symposia, Vancouver, British Columbia, CANADA, January 21 - 26, 2018.
Wehmas, L., C. Wood, R. Gagne, A. Williams, C. Yauk, M. Gosink, D. Dalmas, R. Hao, R. O'Lone, AND S. Hester. Demodifying RNA for Transcriptomic Analyses of Archival Formalin-Fixed Paraffin-Embedded Samples. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 162(2):535-547, (2018). https://doi.org/10.1093/toxsci/kfx278
Catron, T., A. Swank, L. Wehmas, D. Phelps, J. McCord, R. Singh, J. Sobus, S. Keely, N. Brinkman, C. Wood, M. Strynar, AND T. Tal. Developmental estradiol exposure results in microbiota-dependent effects on locomotor activity in larval zebrafish. Society of Environmental Toxicology and Chemistry (SETAC), Sacramento, California, November 04 - 08, 2018.
Catron, T., S. Keely, N. Brinkman, A. Swank, L. Wehmas, D. Phelps, J. Sobus, J. McCord, E. Wheaton, C. Wood, A. Kvasnicka, S. Gaballah, M. Strynar, AND T. Tal. Differential effects of exposure to bisphenol analogues and estradiol on zebrafish host-associated microbiota and behavior. Microbiome Consortium Symposium, Durham, NC, May 15, 2018.
Catron, T., S. Keely, N. Brinkman, A. Swank, L. Wehmas, D. Phelps, J. Sobus, J. McCord, E. Wheaton, C. Wood, A. Kvasnicka, S. Gaballah, M. Strynar, AND T. Tal. Differential effects of exposure to bisphenol analogues and estradiol on zebrafish host-associated microbiota and behavior. Carolinas Society of Environmental Toxicology and Chemistry, Durham, NC, April 25 - 27, 2018.
Catron, T., S. Keely, N. Brinkman, A. Swank, L. Wehmas, D. Phelps, J. Sobus, J. McCord, E. Wheaton, C. Wood, A. Kvasnicka, S. Gaballah, M. Strynar, AND T. Tal. Differential effects of exposure to bisphenol analogues and estradiol on zebrafish host-associated microbiota and neurobehavior. Triangle Zebrafish Symposium, Durham, NC, May 14, 2018.