Science Inventory

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Thomas, R. NAMs 101: The Basics and the EPA NAM Work Plan. American Chemistry Council Webinar, RTP, NC, October 18, 2023. https://doi.org/10.23645/epacomptox.24421714

Schmeisser, S., A. Miccoli, M. von Bergen, E. Berggren, A. Braeuning, W. Busch, C. Desaintes, A. Gourmelon, R. Grafström, J. Harrill, T. Hartung, M. Herzler, G. Kass, N. Kleinstreuer, M. Leist, M. Luijten, P. Marx-Stoelting, O. Poetz, B. van Ravenzwaay, R. Roggeband, V. Rogiers, A. Roth, P. Sanders, R. Thomas, A. Vinggaard, M. Vinken, B. van de Water, A. Luch, AND T. Tralau. New Approach Methodologies in human regulatory toxicology – not if, but how and when! ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 178:108082, (2023). https://doi.org/10.1016/j.envint.2023.108082

Thomas, R. Overview of EPA Efforts. EPA – NIH/NTP/DTT – RISKHUNT3R Meeting at the Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.23620284

Friedman, K., M. Foster, L. Pham, M. Feshuk, S. Watford, J. Wambaugh, R. Judson, R. Setzer, AND R. Thomas. Reproducibility of organ-level effects in repeat dose animal studies. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 28:100287, (2023). https://doi.org/10.1016/j.comtox.2023.100287

Browne, P., K. Friedman, K. Boekelheide, AND R. Thomas. Rethinking How Adversity is Evaluated for New Approach Methods (NAMs). To be Presented at World Congress 12, Niagara FallsC, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.24045309

Thomas, R. Understanding the Impacts of Chemicals in Environmental Health- A Need for Data or Change in Perspective? NC Symposium on Life/Data Sciences, Precision Medicine and Environmental Health, RTP, NC, May 08, 2023. https://doi.org/10.23645/epacomptox.22788434

Thomas, R. Update on the EPA Biennial NAM Conference and U.S. NAS Committee on Uncertainty and Variability in Traditional Toxicity Testing Models (OECD WPHA). Economic Co-operation and Development (OECD) Working Party for Hazard Assessment Update Meeting June 2023, Paris, FRANCE, June 27 - 28, 2023. https://doi.org/10.23645/epacomptox.23587179

Thomas, R. VOI BOSC Review Agenda and Charge Questions. VOI BOSC, Durham, NC, July 25 - 26, 2023. https://doi.org/10.23645/epacomptox.23737269

Price, P., B. Hubbell, S. Hagiwara, G. Paoli, D. Krewski, A. Guiseppi-Elie, M. Gwinn, N. Adkins, AND R. Thomas. A Framework that Considers the Impacts of Time, Cost, and Uncertainty in the Determination of the Cost Effectiveness of Toxicity-Testing Methodologies. RISK ANALYSIS. Blackwell Publishing, Malden, MA, 42(4):707-729, (2022). https://doi.org/10.1111/risa.13810

Wambaugh, J., K. Paul-Friedman, A. Harrill, K. Isaacs, T. Buckley, J. Cowden, C. Deisenroth, M. Devito, P. Egeghy, J. Harrill, S. Hunter, R. Judson, A. Richard, C. Ring, R. Sayre, Amar V. Singh, J. Sobus, E. Ulrich, B. Wetmore, A. Williams, AND R. Thomas. A Vision for Next Generation Risk Assessment at the U.S. Environmental Protection Agency. RISK-HUNT3R Face-to-Face Kickoff Meeting, Egmond aan Zee, NETHERLANDS, July 05 - 07, 2022. https://doi.org/10.23645/epacomptox.20498850

Wambaugh, J., M. Beal, M. Devito, S. Ferguson, M. Hughes, R. Judson, I. Moffat, A. Nong, A. Paini, K. Paul-Friedman, R. Thomas, AND B. Wetmore. Characterizing High Throughput Toxicokinetics for Chemical Decision Making. ISES, Lisbon, N/A, PORTUGAL, September 25 - 29, 2022. https://doi.org/10.23645/epacomptox.21126658

Hopperstad, K., D. DeGroot, T. Zurlinden, C. Brinkman, R. Thomas, AND C. Deisenroth. Chemical Screening in an Estrogen Receptor Transactivation Assay with Metabolic Competence. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 187(1):112-126, (2022). https://doi.org/10.1093/toxsci/kfac019

Hopperstad, K., D. DeGroot, T. Zurlinden, C. Brinkman, R. Thomas, AND C. Deisenroth. Chemical Screening in an Estrogen Receptor Transactivation Assay with Metabolic Competence (SOT 22). Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San Diego, California, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19747465

Thomas, R. Current Status of EPA NAM Effort and Key Goals for the Meeting. US EPA's Third Conference on the State of the Science on Development and Use of New Approach Methods (NAMs) for Chemical Safety Testing, Washington, DC, October 12 - 13, 2022. https://doi.org/10.23645/epacomptox.21325800

Buckley, T., A. Biales, P. Egeghy, A. Richard, J. Sobus, E. Ulrich, K. Isaacs, J. Wambaugh, C. Ring, R. Sayre, Tom Purucker, A. Williams, AND R. Thomas. Defining the Cutting-Edge to the US EPA's Computational Exposure Science. ISES, Lisbon, PORTUGAL, September 25 - 29, 2022. https://doi.org/10.23645/epacomptox.21121363

Thomas, R. Developing NAMs for Regulatory Risk Assessment at US EPA – Experience, State-of-the-Art, Lessons Learned. ONE- Health, Environment, Society-Conference 2022, Virtual, Brussels, BELGIUM, June 21 - 24, 2022.

Thomas, R. EPA Overview for the NAS Committee on Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for NAMs for use in Human Health Risk Assessment. National Academies of Sciences, Engineering, and Medicine Committee Public Meeting, Virtual, NC, July 28 - 29, 2022. https://doi.org/10.23645/epacomptox.20411676

Beal, M., M. Gagne, S. Kulkarni, G. Patlewicz, R. Thomas, AND T. Barton-Maclaren. Implementing in vitro Bioactivity Data to Modernize Priority Setting of Chemical Inventories. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 39(1):123-139, (2022). https://doi.org/10.14573/altex.2106171

Thomas, R. Keys to the Development and Application of Emerging Science at the US EPA. Organization for Economic Co-operation and Development (OECD) Working Group of National Coordinators of the Test Guidelines Programme (WNT), RTP, NC, November 15, 2022. https://doi.org/10.23645/epacomptox.21699071

Thomas, R. NAMs Paradox: When an Unstoppable Force Meets an Immovable Object. Alliance for Risk Assessment Workshop XIII, Virtual, NC, February 15, 2022. https://doi.org/10.23645/epacomptox.19172135

Thomas, R., T. Henry, AND Jeffrey Dawson. Overview of EPA National PFAS Testing Strategy and Related Studies. White House Office of Science and Technology Policy (JSC EIPH PFAS Strategy Team), RTP, NC, July 25, 2022. https://doi.org/10.23645/epacomptox.21720302

Thomas, R., J. Dawson, T. Henry, AND A. Lowit. Research to Inform the EPA National PFAS Testing Strategy. The Science of PFAS Exposure and Effects on Human Health Webinar, RTP, NC, December 08, 2022. https://doi.org/10.23645/epacomptox.21698348

Thomas, R. The Development, Evaluation, and Application of New Approach Methods at US EPA. International Council of Chemical Association’s Long-Range Research Initiative (ICCA-LRI) WORKSHOP, Yokohama, Virtual, JAPAN, June 20 - 21, 2022. https://doi.org/10.23645/epacomptox.20188196

Patlewicz, G., A. Richard, A. Williams, R. Judson, AND R. Thomas. Towards Reproducible Structure-Based Chemical Categories for PFAS to Inform and Evaluate Toxicity and Toxicokinetic Testing. ASCCT, Chapel Hill, NC, October 19 - 21, 2022. https://doi.org/10.23645/epacomptox.21231461

Patlewicz, G., A. Richard, A. Williams, R. Judson, AND R. Thomas. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 24:100250, (2022). https://doi.org/10.1016/j.comtox.2022.100250