Science Inventory

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LaLone, C. SeqAPASSv5.0: An emphasis on rapid data synthesis and interpretation. CompTox Communities of Practice Webinar, Duluth, MN, December 03, 2020. https://doi.org/10.23645/epacomptox.13302827

Blatz, D. AND C. LaLone. Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) to understand chemical susceptibility across bee species. Bayer AG; Research and Development, Crop Science Webinar, Duluth, MN, June 30, 2020. https://doi.org/10.23645/epacomptox.12507410

Doering, J., G. Ankley, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Fay, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. Lalone, S. Poole, E. Randolph, C. Tilton, AND D. Villeneuve. A cross-species model for predicting reproductive dysfunction in fishes exposed to aromatase inhibiting chemicals. Twin Ports Early-Career Researchers Symposium, Duluth, MN, March 28, 2019.

Lalone, C. Adverse outcome pathways: Creating a sustainable framework for decision-making. International Conference on Marine Pollution and Ecotoxicology, Hong Kong, N/A, HONG KONG, June 11 - 14, 2019.

Hecker, M. AND C. LaLone. Adverse outcome pathways: Moving from a scientific concept to a internationally accepted framework. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 38(6):1152-1163, (2019). https://doi.org/10.1002/etc.4385

Doering, J., D. Villeneuve, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Faye, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. Lalone, S. Poole, E. Randolph, C. Tilton, AND G. Ankley. Aromatase inhibition in fishes with group-synchronous oocyte development: The importance of reproductive traits. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.

Doering, J., G. Ankley, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Fay, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. LaLone, S. Poole, E. Randolph, C. Tilton, AND Dan Villeneuve. Cross-species Applicability of a quantitative AOP describing inhibition of aromatase activity leading to reproductive dysfunction in fishes. SETAC Europe, Helsinki, N/A, FINLAND, May 26 - 30, 2019.

Elias, M., G. Ankley, M. Barron, C. Bergeron, D. Eignor, R. Erickson, D. Hoff, A. Jarvis, J. Justice, C. Lalone, D. Mount, D. Villeneuve, AND K. Gallagher. Developing protective aquatic life values for data-limited chemicals considerations for PFAS. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.

Kittelson, A., J. Olker, J. Doering, C. Lalone, D. Villeneuve, AND G. Ankley. Development of adverse outcome pathways relevant to the ecological effects of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic, Durham, NC, August 12 - 15, 2019.

Doering, J., Dan Villeneuve, K. Fay, E. Randolph, K. Jensen, M. Kahl, C. LaLone, AND G. Ankley. Differential sensitivity to in vitro inhibition of cytochrome P450 aromatase (CYP19) activity among 18 freshwater fishes. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 170(2):394-403, (2019). https://doi.org/10.5061/dryad.nn94830

Lalone, C., J. Doering, W. Cheng, H. Peng, AND C. Ng. Employing the Sequence Alignment to Predict Across Species Susceptibility tool to inform bioaccumulation potential of per- and polyfluorinated alkyl substances across species. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.

Tollefsen, K., M. Cronin, L. Evenseth, C. Mellor, J. Firman, T. Iguchi, I. Sylte, K. Toyota, Y. Song, C. Lalone, AND D. Villeneuve. Endocrine disruption in crustaceans - a “new” environmental challenge? International Symposium on Pollutant Responses In Marine Organisms, Charleston, SC, May 19 - 22, 2019.

Finnegan, C., J. Doering, AND C. LaLone. Enhancing the utility of the Sequence Alignment to Predict Across Species Susceptibility tool. SETAC Europe, Helsinki, N/A, FINLAND, May 26 - 30, 2019.

Cheng, W., J. Doering, C. Lalone, AND C. Ng. Estimating the bioaccumulation potential of per-and polyfluoroalkyl substances (PFAS) across species by integrative in silico approaches. Allegheny-Erie Society of Toxicology Regional Chptr Modernizing Toxicity Testing/ Risk Assessment, Pittsburgh, PA, May 01 - 02, 2019.

Vliet, S. AND C. Lalone. Evaluation of cross-species conservation of the androgen receptor and the basis for identifying androgenic chemicals in nonmammalian taxa using mammalian test systems. US EPA-Japanese Bilateral, Washington,D.C., N/A, October 22 - 23, 2019.

Doering, J. AND C. LaLone. Extrapolation of chemical susceptibilities across humans, domesticated animals, wildlife, and plants using the SeqAPASS tool. SETAC Europe 2019, Helsinki, N/A, FINLAND, May 26 - 30, 2019.

Weiziao, C., J. Doering, C. LaLone, AND C. Ng. Integrative modeling approaches for insight into the behavior of per- and polyfluorinated alkyl substances (PFAS) across scales and ecosystems. Association of Environmental Engineering and Science Professors, Tempe, AZ, May 14 - 16, 2019.

Lalone, C. New frontiers in species extrapolation: Tools for toxicology. UMD, Dept. of Biology, Duluth, MN, March 08, 2019.

Simha, A., K. Houck, C. Lalone, A. Bone, R. Judson, M. Martin, D. Villeneuve, G. Ankley, A. Medvedev, AND S. Makarov. Novel In Vitro Approach to Assess Multiple Species’ Susceptibility to Potential Endocrine Disruptors. Presented at Endocrine Disruption conference at NIEHS, RTP, NC, April 05, 2019. https://doi.org/10.23645/epacomptox.8023451

Doering, J., D. Villeneuve, S. Poole, B. Blackwell, K. Jensen, M. Kahl, A. Kittelson, D. Feifarek, C. Tilton, C. Lalone, AND G. Ankley. Quantitative response-response relationships linking aromatase inhibition to decreased fecunditiy are conserved across three fishes with asynchronous oocyte development. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 53(17):10470-10478, (2019). https://doi.org/10.1021/acs.est.9b02606

Lalone, C., L. Gessner, M. Jones, J. Franzosa, AND C. Baghdikian. Science in Action: SeqAPASS Sequence Alignment to Predict Across Species Susceptibility . U.S. EPA Office of Research and Development, Washington, DC, EPA/600/F-19/019, 2019.

Lalone, C., D. Blatz, AND C. Finnegan. Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) version 4.0 user guide. U.S. EPA Office of Research and Development, Washington, DC, EPA/600/R-19/156, 2019.

Doering, J., G. Ankley, B. Blackwell, K. Dean, C. Finnegan, C. LaLone, S. Poole, AND Dan Villeneuve. Strategically selecting test species using the sequence alignment to predict across Species Susceptibility (SeqAPASS) tool. SETAC EUROPE, Helsinki, N/A, FINLAND, May 26 - 30, 2019.

Lalone, C. The ECOTOX Knowledgebase Pipeline: From literature search to data extraction AND SeqAPASS tool briefing. Interagency Coordinating Committee for Validation of Alternative Methods (ICCVAM) Eco-Workgroup, Duluth, MN, March 06, 2019.

Olker, J., C. Elonen, C. Lalone, S. Erickson, M. Skopinski, A. Pilli, AND D. Hoff. The ECOTOXicology Knowledgebase: Curated ecologically-relevant toxicity data for risk assessments, criteria derivation, and environmental research. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.