Science Inventory

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Fay, K., M. Embry, M. Bernard, I. Bischof, J. Davis, J. Domoradzki, M. Halder, X. Han, K. Johanning, H. Laue, D. Nabb, J. Nichols, C. Schlechtriem, H. Segner, L. van der Wal, AND J. Weeks. In vitro to In vivo extrapolation of hepatic metabolism in fish: An inter-laboratory comparison of In vitro methods. SETAC North America, Salt Lake City, UT, November 01 - 05, 2015.

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Intra- and inter-laboratory reliability of a cryopreserved trout hepatocyte assay for the prediction of chemical bioaccumulation potential. ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 48(14):8170-8178, (2014).

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Optimizing the use of rainbow trout hepatocytes for bioaccumulation assessments with fish. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, 44(4):345-351, (2014).

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Inter-laboratory comparison of clearance rates of xenobiotics by cryopreserved trout hepatocytes for the prediction of bioaccumulation potential. Presented at Society of Toxicology, March 10 - 14, 2013.

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Inter-laboratory comparison of xenobiotic clearance rates determined using cryopreserved trout hepatocytes for improving bioaccumulation predictions. Presented at Health and Environmental Sciences Institute, Duluth, MN, November 01, 2013.

Berninger, J., K. Fay, C. LaLone, D. Dreier, E. Durhan, L. Makynen, M. LEE, Dan Villeneuve, G. Ankley, AND J. Nichols. Prioritizing and selecting pharmaceuticals to test the read-across approach: using human clearance rates to predict biotransformation in fish. Presented at SETAC, Nashville, TN, November 17 - 21, 2013.

Fay, K., C. LaLone, E. Durhan, M. Lee, L. Makynen, Dan Villeneuve, G. Ankley, J. Nichols, AND J. Berninger. Use of human clearance rates to predict the biotransformation of pharmaceuticals by fish: A test of the read-across approach. Presented at SETAC, Nashville, TN, November 17 - 21, 2013.

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Use of isolated hepatocytes to predict measured hepatic clearance of five polyaromatic hydrocarbons by perfused trout livers. Presented at Society of Toxicology, March 10 - 14, 2013.

Fay, K. Using cryopreserved trout hepatocytes to obtain clearance rates for improving bioaccumulation predictions. Presented at SETAC, Nashville, TN, November 17 - 21, 2013.

Nichols, J., A. Hoffman, P. Fitzsimmons, K. Fay, AND T. Ter Laak. Predicting the accumulation of well-metabolized chemicals by fish from measured rates of in vitro intrinsic clearance: Progress made and challenges ahead. Presented at Invited oral presentation, Stockholm University.

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Use of isolated hepatocytes to predict measured hepatic clearance of five polyaromatic hydrocarbons by perfused trout livers, invited presentation. Presented at Toxicology Graduate Student Seminar, October 03, 2012.

NICHOLS, J. W., A. D. HOFFMAN, P. N. FITZSIMMONS, K. A. FAY, AND T. TER LAAK. Hepatic Clearance of Six Polyaromatic Hydrocarbons by Isolated Perfused Trout Livers: Prediction from Liver S9 Fractions and Isolated Hepatocyte. Presented at pollutant responses in marine organisms, Long Beach, CA, May 15 - 18, 2012.