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Records 51 to
75
of 265 records from author Timothy Shafer
2022
Villeneuve, D., T. Shafer, S. Padilla, J. Harrill, AND M. Jankowski. Evaluating the bioactivity of the ubiquitous tire preservative 6PPD and its quinone transformation product. National EPA Tribal Science Council, Fall 2022 Face-to-Face Meeting, Research Triangle Park, NC, December 06 - 08, 2022. https://doi.org/10.23645/epacomptox.21714164
Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, A. Richard, G. Patlewicz, B. Wetmore, K. Paul-Friedman, AND T. Shafer. Evaluation of Per- and Poly fluoroalkyl Substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computational Toxicology (ASCCT) Conference, Durham, NC, October 19 - 21, 2022. https://doi.org/10.23645/epacomptox.21859527
Carpenter, A., K. Carstens, M. Martin, T. Shafer, AND K. Paul-Friedman. Evaluation of the ToxCast Assay Suite for Detection of Neuroactivity. 11th annual meeting of the American Society for Cellular and Computational Toxicology (ASCCT), RTP, NC, October 19 - 21, 2022. https://doi.org/10.23645/epacomptox.21728429
Carpenter, A., K. Carstens, M. Martin, T. Shafer, AND K. Paul-Friedman. Evaluation of the ToxCast Assay Suite for Detection of Neuroactivity (NC SOT 22). North Carolina Society of Toxicology Meeting 2022, RTP, North Carolina, January 19, 2022. https://doi.org/10.23645/epacomptox.19096841
Carpenter, A., K. Carstens, M. Martin, T. Shafer, AND K. Paul-Friedman. Evaluation of the ToxCast Assay Suite for Detection of Neuroactivity (SOT 22). Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San DIego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19411679
Carpenter, A., K. Carstens, M. Martin, T. Shafer, AND K. Paul-Friedman. Evaluation of the ToxCast Assay Suite for the Detection of Neuroactivity. Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19411679
Kreutz, A., B. Wetmore, T. Shafer, K. Paul-Friedman, AND J. Wambaugh. In vitro in vivo extrapolation (IVIVE) for neurodevelopment: toxicokinetics and in vitro point of departure evaluation of putative developmental neurotoxicants. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19358411
Kreutz, A., T. Shafer, K. Paul-Friedman, J. Wambaugh, AND B. Wetmore. In vitro-in vivo extrapolation (IVIVE) for neurodevelopment: Toxico-kinetics and in vitro point of departure evaluation of putative developmental neurotoxicants. FutureTox V, Chapel Hill, NC, May 10 - 11, 2022. https://doi.org/10.23645/epacomptox.19701313
Kreutz, A., T. Shafer, K. Paul-Friedman, J. Wambaugh, AND B. Wetmore. In vitro-in vivo extrapolation (IVIVE) for neurodevelopment: Toxicokinetics and in vitro point of departure evaluation of putative developmental neurotoxicants. NC Society of Toxicology, Durham, NC, January 19, 2022. https://doi.org/10.23645/epacomptox.18635066
Marable, C., C. Frank, R. Seim, S. Hester, Matt Henderson, B. Chorley, AND T. Shafer. Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in vitro Neural Network Formation. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 186(1):118-133, (2022). https://doi.org/10.1093/toxsci/kfab151
Carstens, K., A. Carpenter, M. Martin, J. Harrill, T. Shafer, AND K. Friedman. Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 187(1):62-79, (2022). https://doi.org/10.1093/toxsci/kfac018
Martin, M., S. Padilla, K. Paul-Friedman, D. Herr, Steve Simmons, J. Hedge, AND T. Shafer. Novel approaches using the microelectrode array to measure network function in larval zebrafish (INA 2022). International Neurotoxicology Association (INA) Meeting 2022, Durham, North Carolina, May 16 - 22, 2022. https://doi.org/10.23645/epacomptox.20135990
Shafer, T. AND T. Gibson. The use of new approach methodologies (NAMs) to derive extrapolation factors and evaluate developmental neurotoxicity for human health risk assessment (Report). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-22/291, 2022.
Shafer, T. Update on US EPA application of the DNT In Vitro Battery. OECD Developmental Neurotoxicity Expert Panel, Virtual meeting, North Carolina, March 10 - 11, 2022. https://doi.org/10.23645/epacomptox.19368977
2021
Muriana, A., A. Alzualde, J. Hsieh, K. Ryan, M. Behl, A. Terron, C. Woodland, N. Kluver, E. Hessel, L. Ellis, L. Truong, R. Tanguay, M. Sachana, B. Hill, S. Padilla, T. Shafer, J. Legradi, V. Schiavone, D. Rubbini, V. Di Donato, AND J. Terriente. An Inter-laboratory Case Study to Harmonize Zebrafish Light-Dark Transition Test to Predict Developmental Neurotoxicity (WC11). 11th World Congress on Alternative and Animal Use in the Life Sciences 2021, Maastricht, N/A, NETHERLANDS, August 22 - 26, 2021. https://doi.org/10.23645/epacomptox.17928983
Martin, M., Nancy C. Baker, W. Boyes, K. Carstens, M. Culbreth, M. Gilbert, J. Harrill, J. Nyffeler, S. Padilla, K. Paul-Friedman, AND T. Shafer. An expert-driven literature review of “negative” reference chemicals for developmental neurotoxicity (DNT) assay evaluation. Society of Toxicology 2021 Virtual Annual Meeting, Virtual, North Carolina, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14226326
Alzualde, A., J. Hsieh, L. Ellis, V. Schiavone, L. Truong, J. Legradi, D. Rubbini, C. Woodland, N. Kluver, K. Ryan, M. Behl, J. Terriente, A. Muriana, R. Tanguay, M. Sachana, A. Price, B. Hill, S. Padilla, T. Shafer, AND E. Hessel. An inter-laboratory case study to determine the added value of the Zebrafish Light-dark transition test to predict developmental neurotoxicity. European Society of Environmental Toxicology and Chemistry (SETAC), NA, Virtual Meeting, May 03 - 06, 2021. https://doi.org/10.23645/epacomptox.17704253
Hessel, E., T. Shafer, S. Padilla, B. Hill, L. Truong, R. Tanguay, J. Hsieh, K. Ryan, M. Behl, L. Ellis, V. Schiavone, D. Rubbini, J. Terriente, A. Alzualde, A. Muriana, J. Legradi, C. Woodland, M. Sachana, A. Price, AND N. Kluver. An inter-laboratory case study to determine the added value of the Zebrafish Light-dark transition test to predict developmental neurotoxicity: Report from OECD DNT Expert Group. Society of Toxicology 2021 Virtual Annual Meeting, NA, Virtual Meeting, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.20032085
Carstens, K., A. Carpenter, M. Martin, J. Harrill, K. Paul-Friedman, AND T. Shafer. Analyzing multi-dimensional developmental neurotoxicity new approach methodologies: computational approaches to identify phenotypes. American Society for Cellular and Computational Toxicology (ASCCT) annual meeting, Virtual meeting, NC, October 12 - 14, 2021. https://doi.org/10.23645/epacomptox.16923994
Shafer, T. Applying assays from the In Vitro Developmental Neurotoxicity Testing Battery to Compare DL- to L-Glufosinate Activity. EPA-Office of Pesticides ToxSac CSS Webinar, RTP, North Carolina, May 20, 2021. https://doi.org/10.23645/epacomptox.17372606
Carstens, K., A. Carpenter, M. Martin, J. Harrill, T. Shafer, AND K. Paul-Friedman. Computational approaches to evaluate in vitro New Approach Methodologies (NAMs) for Developmental Neurotoxicity (DNT). EPA Developmental Neurotoxicology Journal Club, RTP, North Carolina, June 30, 2021. https://doi.org/10.23645/epacomptox.16709170
Shafer, T. Developmental Neurotoxicity (DNT) in vitro Battery as an Alternative to DNT in vivo Guideline Studies Used by OPP. U.S. EPA ORD Board of Scientific Counselors Subcommittee Chemical Safety for Sustainability and Health and Environmental Risk Assessment National Research Programs, RTP, North Carolina, February 02 - 05, 2021. https://doi.org/10.23645/epacomptox.13922930
Carstens, K., A. Carpenter, M. Martin, J. Harrill, T. Shafer, AND K. Paul-Friedman. Evaluation of in vitro New Approach Methodologies for Developmental Neurotoxicity. Society of Toxicology 2021 Virtual Annual Meeting, RTP (Virtual), NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.17950670
Shafer, T. Examples of How Data from in vitro Developmental Neurotoxicity Assays Are Being Used to Make Decisions About Chemicals. Presented at 11th World Congress on Alternatives and Animal Use in the Life Sciences, Virtual, Maastricht, NETHERLANDS, August 23 - September 02, 2021. https://doi.org/10.23645/epacomptox.16645420
Kreutz, A., T. Shafer, K. Paul-Friedman, J. Wambaugh, AND B. Wetmore. In vitro-in vivo extrapolation (IVIVE) for neurodevelopment: Toxicokinetics and in vitro point of departure evaluation of putative developmental neurotoxicants. 10th Annual Meeting of the American Society for Cellular and Computational Toxicology, Virtual, Virtual, October 12 - 14, 2021. https://doi.org/10.23645/epacomptox.16778056