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SERRANO, J. A., B. WITHUHN, L. HIGGINGS, J. J. KORTE, G. W. HOLCOMBE, P. A. KOSIAN, J. E. TIETGE, AND S. J. DEGITZ. 2DPAGE AND ITRAQ LABELING: COMPLEMENTARY TOOLS FOR IN-VIVO ASSESSMENT/DIAGNOSIS OF AMPHIBIAN THYROID AXIS-DISRUPTING CHEMICALS. Presented at Society of Toxicology (SOT) 2006 Conference, San Diego, CA, March 05 - 09, 2006.

TIETGE, J. E., M. W. HORNUNG, K. R. THOEMKE, J. J. KORTE, J. W. NICHOLS, AND S. J. DEGITZ. A SYSTEMS APPROACH TO CHARACTERIZING AND PREDICTING THYROID TOXICITY USING AN AMPHIBIAN MODEL. Presented at Interact 2006, Perth, AUSTRALIA, September 24 - 28, 2006.

SERRANO, J. A., J. E. TIETGE, AND S. J. DEGITZ. ADVANCED PROTEOMICS AND BIOINFORMATICS TOOLS IN TOXICOLOGY RESEARCH: OVERCOMING CHALLENGES TO PROVIDE SIGNIFICANT RESULTS. Presented at Reproductive Toxicology Division Meeting, RTP, NC, May 18, 2006.

KORTE, J. J., H. M. KERR, M. BUGGE, L. M. KORTE, P. A. KOSIAN, G. W. HOLCOMBE, J. E. TIETGE, AND S. J. DEGITZ. DEIODINASE TYPE I, II, AND III EXPRESSION IN AMPHIBIAN PITUITARY, THYROID, AND LIMB BUD AT KEY STAGES OF DEVELOPMENT AND AFTER EXPOSURE TO THE THYROID HORMONE SYNTHESIS MODULATORS: METHIMAZOLE, PERCHLORATE AND PROPYLTHIOURACIL. Presented at Society of Toxicology (SOT) 2006 Conference, San Diego, CA, March 05 - 09, 2006.

ZHANG, F., G. W. HOLCOMBE, P. A. KOSIAN, J. E. TIETGE, N. VELDHOEN, S. J. DEGITZ, JR., AND C. C. HELBING. Evaluation of Gene Expression Endpoints in the Context of a Xenopus laevis Metamorphosis-based Bioassay to Detect Thyroid Hormone Disruptors. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 76((2006)):24-36, (2006).

TIETGE, J. E., S. J. DEGITZ, G. T. ANKLEY, L. TOUART, AND A. GOURMELON. INTERNATIONAL COLLABORATION IN THE DEVELOPMENT OF ENDOCRINE DISRUPTOR TESTING GUIDELINES FOR FISH AND AMPHIBIANS. Presented at Interact 2006, Perth, AUSTRALIA, September 24 - 26, 2006.

THOEMKE, K. R., J. J. KORTE, L. M. KORTE, J. M. OLSON, J. E. TIETGE, AND S. J. DEGITZ. REGULATION OF THE THYROID AXIS IN DEVELOPING XENOPUS LAEVIS. Presented at 77th Annual ATA Meeting, Phoenix, AZ, October 11 - 15, 2006.

HORNUNG, M. W., K. R. THOEMKE, J. J. KORTE, J. W. NICHOLS, P. K. SCHMIEDER, J. E. TIETGE, AND S. J. DEGITZ. SYSTEMS APPROACH TO CHARACTERIZING AND PREDICTING THYROID TOXICITY. Presented at McKim Conference on the Use of QSARs and Aquatic Toxicology in Risk Assessment, Duluth, MN, June 27 - 29, 2006.

THOEMKE, K. R., J. J. KORTE, M. W. HORNUNG, M. BUGGE, L. M. KORTE, G. W. HOLCOMBE, J. E. TIETGE, AND S. J. DEGITZ. THE PITUITARY RESPONSE TO CHEMICAL THYROID AXIS DISRUPTION IN XENOPUS LAEVIS. Presented at Society of Toxicology (SOT) 2006 Conference, San Diego, CA, March 05 - 09, 2006.

HORNUNG, M. W., S. J. DEGITZ, K. R. THOEMKE, J. J. KORTE, P. A. KOSIAN, L. M. KORTE, M. BUGGE, AND J. E. TIETGE. TIME AND DOSE-DEPENDENT THYROID HORMONE RELEASE FROM XENOPUS THYROID GLAND CULTURES IN RESPONSE TO THYROID STIMULATING HORMONE AND INHIBITION BY METHIMAZOLE. Presented at Society of Toxicology (SOT) 2006 Conference, San Diego, CA, March 05 - 09, 2006.

SERRANO, J. A., B. WITTHUHN, L. HIGGINS, L. E. ANDERSON, J. J. KORTE, G. W. HOLCOMBE, P. A. KOSIAN, H. KERR, J. E. TIETGE, AND S. J. DEGITZ. 2D-PAGE AND ITRAQ PEPTIDE-MASS LOGGING: EFFECTIVE COMPLEMENTARY TOOLS FOR IN VIVO ASSESSMENT/DIAGNOSIS OF THYROID HORMONE AXIS-DISRUPTING CHEMICALS IN ANURAN SPECIES. Presented at SETAC Annual Meeting, Baltimore, MD, November 13 - 14, 2005.

HORNUNG, M. W., J. E. TIETGE, J. J. KORTE, M. BUGGE, L. M. KORTE, AND S. J. DEGITZ. CHARACTERIZATION OF A XENOPUS LAEVIS THYROID GLAND EXPLANT CULTURE SYSTEM FOR TESTING THE EFFECTS OF CHEMICALS ON THYROID GLAND FUNCTION. Presented at SETAC Annual Meeting, Baltimore, MD, November 13 - 17, 2005.

SERRANO, J. A., B. WITTHUHN, L. HIGGINS, L. E. ANDERSON, J. E. TIETGE, J. J. KORTE, G. W. HOLCOMBE, P. A. KOSIAN, D. E. HAMMERMEISTER, MOHANNED J. CHOWDHURY, AND S. J. DEGITZ, JR. DIFFERENTIAL PROTEIN PROFILING OF XENOPUS LAEVIS BRAIN CELLS BY GEL- AND ITRAQTM PEPTIDE-BASED LABELING BIOTECHNIQUES FOLLOWING EXPOSURE TO MODEL T4 SYNTHESIS INHIBITORS: APPLICATION TO THE ASSESSMENT/DIAGNOSIS OF THYROID HORMONE AXIS DISRUPTING CHEMICALS. Presented at Minnesota Chromatography Forum Symposium, Minneapolis, MN, May 17 - 19, 2005.

KORTE, J. J., H. KERR, S. L. BATTERMAN, G. W. HOLCOMBE, P. A. KOSIAN, J. E. TIETGE, AND S. J. DEGITZ, JR. GENE EXPRESSION OF THE AMPHIBIAN HPT-AXIS IN NORMAL DEVELOPMENT AND AFTER EXPOSURE TO THE MODULATORS METHIMAZOLE, PERCHLORATE, AND PROPYLTHIOURACIL. Presented at Society of Toxicology (SOT) Meeting, New Orleans, LA, March 06 - 10, 2005.

SERRANO, J. A., B. WITTHUHN, L. HIGGINS, L. ANDERSON, J. E. TIETGE, J. J. KORTE, G. W. HOLCOMBE, P. A. KOSIAN, S. J. DEGITZ, JR., AND H. KERR. ITRAQ MASS SPECTROMETRIC PROTEOMIC APPLICATIONS FOR IN VIVO TOXICOLOGY STUDIES OF AMPHIBIAN SPECIES: DATA HANDLING AND INTERPRETATION USING PEPTIDE-TAGGING SOFTWARE. Presented at American Society for Mass Spectrometry (ASMS), San Antonio, TX, June 03 - 10, 2005.

Tietge, J E., G W. Holcombe, K. M. Flynn, P A. Kosian, J J. Korte, L E. Anderson, D. C. WOLF, AND S. J. DEGITZ. METAMORPHIC INHIBITION OF XENOPUS LAEVIS BY SODIUM PERCHLORATE: EFFECTS ON DEVELOPMENT AND THYROID HISTOLOGY. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. SETAC Press, Pensacola, FL, 24(4):926-933, (2005).

TIETGE, J. E. OVERVIEW OF ORD'S AQUATIC TOXICOLOGY RESEARCH ON ENDOCRINE-ACTIVE CHEMICALS. Presented at USEPA Workshop on Pharmaceuticals in the Environment, Las Vegas, NV, August 23 - 25, 2005.

Chowdhury, M. J., G W. Holcombe, P A. Kosian, J E. Tietge, AND S J. Degitz. PHENOBARBITAL AFFECTS THYROID HISTOLOGY AND LARVAL DEVELOPMENT IN THE AFRICAN CLAWED FROG XENOPUS LAEVIS. Presented at Society of Toxicology (SOT) Annual Meeting, New Orleans, LA, March 6-10, 2005.

Degitz, S J., G W. Holcombe, K. M. Flynn, P A. Kosian, J J. Korte, AND J E. Tietge. PROGRESS TOWARDS DEVELOPMENT OF AN AMPHIBIAN-BASED THYROID SCREENING ASSAY USING XENOPUS LAEVIS: ORGANISMAL AND THYROIDAL RESPONSES TO THE MODEL COMPOUNDS 6-PROPYLTHIOURACIL, METHIMAZOLE, AND THYROXINE. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 87(2):353-364, (2005).

Serrano, J A., B. Witthuhn, L. Higgins, J E. Tietge, J J. Korte, P A. Kosian, G W. Holcombe, AND S J. Degitz. PROTEIN PROFILING OF XENOPUS LAEVIS BRAIN CELLS FOLLOWING EXPOSURE TO T4-SYNTHESIS INHIBITORS: POTENTIAL APPLICATION TO THE ASSESSMENT/DIAGNOSIS OF XENOBIOTICS THAT PERTURB THE THYROID PATHWAY. Presented at Society of Toxicology (SOT) Annual Meeting, New Orleans, LA, March 6-10, 2005.

SERRANO, J. A., L. HIGGINS, S. J. DEGITZ, J. E. TIETGE, J. J. KORTE, G. W. HOLCOMBE, D. E. HAMMERMEISTER, PAT A. KOSIAN, AND H. KERR. RELATIVE QUANTIFICATION OF PROTEINS IN THE BRAIN OF XENOPUS LAEVIS UPON EXPOSURE TO CHEMICALS IS PERFORMED WITH PEPTIDE MASS TAGS USING ITRAQ TECHNOLOGY. Presented at Minnesota Chromatography Forum Symposium, Minneapolis, MN, May 17 - 19, 2005.

CHOWDHURY, J., G. W. HOLCOMBE, J. J. KORTE, P. A. KOSIAN, A. L. LINNUM, M. BUGGE, J. E. TIETGE, AND S. J. DEGITZ. THYROID DISRUPTION IN XENOPUS BY MICROSOMAL ENZYME INDUCERS: A MULTI-ENDPOINT STUDY WITH PHENOBARBITAL AND PCN. Presented at SETAC Annual Meeting, Baltimore, MD, November 13 - 17, 2005.

Ankley, G T., S J. Degitz, S A. Diamond, AND J E. Tietge. ASSESSMENT OF ENVIRONMENTAL STRESSORS POTENTIALLY RESPONSIBLE FOR MALFORMATIONS IN NORTH AMERICAN ANURAN AMPHIBIANS. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Online, New York, NY, 58(1):7-16, (2004).

Tietge, J E., G T. Ankley, AND S J. Degitz. REPORT ON THE XENOPUS TAIL RESORPTION ASSAY AS A TIER 1 SCREEN FOR THYROID ACTIVE CHEMICALS.

Degitz, S J., G W. Holcombe, P A. Kosian, J E. Tietge, E J. Durhan, AND G T. Ankley. COMPARING THE EFFECTS OF RETINOIC ACID ON AMPHIBIAN LIMB DEVELOPMENT AND LETHALITY: CHRONIC EXPOSURE RESULTS IN LETHALITY NOT LIMB MALFORMATIONS. TOXICOLOGICAL SCIENCES 74:139-146, (2003).