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See all EPA publications for Marina Evans Include records from any EPA source

Records 26 to 50 of 84 records from [ORD-NHEERL] from author Marina Evans

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2008

EVANS, M. V., S. M. DOWD, E. M. KENYON, M. F. HUGHES, AND H. A. EL-MASRI. A PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR intravenous and ingested DIMETHYLARSINIC ACID (DMAV) IN MICE. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 104(2):250-260, (2008).

EL-MASRI, H. A., J. E. SIMMONS, R. A. PEGRAM, R. A. HARRISON, S. YAVANHXAY, S. M. DOWD, AND M. V. EVANS. DEVELOPMENT OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR THE INHALATION OF 2,2,4-TRIMETHYLPENTANE (TMP) IN LONG EVANS RATS. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.

2007

YOKLEY, K. AND M. V. EVANS. AN EXAMPLE OF MODEL STRUCTURE DIFFERENCES USING SENSITIVITY ANALYSES IN PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS OF TRICHLOROETHYLENE IN HUMANS. BULLETIN OF MATHEMATICAL BIOLOGY. Elsevier Science Ltd, New York, NY, 69(8):2591-625, (2007).

YOKLEY, K., M. V. EVANS, AND J. E. SIMMONS. ESTABLISHING CHANGES IN METABOLISM OF CARBON TETRACHLORIDE IN THE PRESENCE OF TRICHLOROETHYLENE IN THE RAT THROUGH THE USE OF PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELING. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

EVANS, M. V., H. M. YANG, T. A. MCDONALD, Y. M. SEY, AND J. E. SIMMONS. PHYSIOLOGICALLY BASED PHARMACOKINEITC (PBPK) MODELING OF METABOLIC INHIBITION FOR INTERACTION BETWEEN TRICHLOROETHYLENE AND CHLOROFORM. Presented at Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.

2006

DEVITO, M. J., M. V. EVANS, M. S. OKINO, B. R. SONAWANE, CHADWICK M. THOMPSON, L. S. BIRNBAUM, K. YOKLEY, C. CORTON, J. LEE, AND A. M. GELLER. EVALUATION OF ALTERED SENSITIVITY OF OLDER ADULTS TO ENVIRONMENTAL AGENTS USING PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELING. Presented at U.S. EPA 2006 Science Forum, Washington, DC, May 16 - 18, 2006.

KENYON, E. M., M. F. HUGHES, C. R. EKLUND, AND M. V. EVANS. EVALUATION OF INTERSPECIES DIFFERENCES IN PHARMACOKINETICS (PK) USING A PBPK MODEL FOR THE PESTICIDE DIMETHYLARSINIC ACID (DMAV) . Presented at 45th Annual Society of Toxicology Meeting 2006, San Diego, CA, March 05 - 09, 2006.

YOKLEY, K. AND M. V. EVANS. MODEL DEVELOPMENT AND EVALUATION FOR TRICHLOROETHYLENE METABOLISM IN HUMANS. Presented at SIAM Annual Meeting, Boston, MA, July 11 - 12, 2006.

EKLUND, C. R., W. K. BOYES, J. E. SIMMONS, AND M. V. EVANS. THE EFFECT OF UNCERTAINTY FACTOR PLACEMENT IN A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL OF TRICHLOROETHYLENE (TCE) FOR ACUTE EXPOSURE GUIDELINE LEVELS (AEGL). . Presented at 45th Annual Society of Toxicology Meeting 2006, San Diego, CA, March 05 - 09, 2006.

2005

Kenyon, E M., M F. Hughes, C R. Eklund, AND M V. Evans. A PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR THE PESTICIDE MONOMETHYLARSONIC ACID (MMA). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.

Evans, M V., R. TORNERO-VELEZ, M J. DeVito, M S. Okino, A M. Geller, J N. Blancato, AND L S. Birnbaum. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMOKINETICS (PBPK) MODEL TO COMPARE DIFFERENCES IN DISPOSITION OF TRICHLOROETHYLENE (TCE) IN ADULT VERSUS ELDERLY RATS. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.

Boyes, W K., M. V. EVANS, C EKLUND, P. Janssen, AND J E. Simmons. DURATION ADJUSTMENT OF ACTUE EXPOSURE GUIDELINE LEVEL (AEGL) VALUES FOR TRICHLOROETHYLENE (TCE) USING A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL. RISK ANALYSIS 25(3):677-686, (2005).

Granville, C. A., M. K. Ross, R TORNERO-VELEZ, N. M. Hanley, A. Gold, A M. Richard, K. Funasaka, A H. Tennant, A D. Kligerman, M V. Evans, AND D M. Demarini. GENOTOXICITY AND METABOLISM OF THE SOURCE-WATER CONTAMINANT 1,1-DICHLOROPROPENE: ACTIVATION BY GSTT1-1 AND STRUCTURE-ACTIVITY CONSIDERATIONS. MUTATION RESEARCH. Elsevier Science BV, Amsterdam, Netherlands, 572(1-2):98-112, (2005).

BOYES, W. K., M. S. BERCEGEAY, TODD T. KRANTZ, M. V. EVANS, V. A. BENIGNUS, AND J. E. SIMMONS. MOMENTARY BRAIN CONCENTRATION OF TRICHLOROETHYLENE PREDICTS THE EFFECTS ON RAT VISUAL FUNCTION. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 87(1):187-196, (2005).

Simmons, J E., M V. Evans, AND W K. Boyes. MOVING FROM EXTERNAL EXPOSURE CONCENTRATION TO INTERNAL DOSE: DURATION EXTRAPOLATION BASED ON PHYSIOLOGICALLY-BASED PHARACOKINETIC-MODEL DERIVED ESTIMATES OF INTERNAL DOSE. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 68(11-12):927-950, (2005).

Bushnell, P J., T E. Samsam, W M. Oshiro, C R. Eklund, AND M V. Evans. ROUTE-DEPENDENT EFFECTS OF TOLUENE ON SIGNAL DETECTION BEHAVIOR IN RATS. Presented at Society of Toxicology, New Orleans, LA, March 06 - 10, 2005.

2004

Evans, M V., F W. Power, C C. Dary, R. TORNERO-VELEZ, AND J. Blancato. APPLICATION OF THE EXPOSURE DOSE ESTIMATING MODEL (ERDEM) TO ASSESSMENT OF DERMAL EXPOSURE IN THE RAT TO MALATHION. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.

Himmelstein, M., S. C. Carpenter, M V. Evans, Hinderliter,PM, AND E M. Kenyon. KINETIC MODELING OF B-CHLOROPRENE METABOLISM:II. THE APPLICATION OF PHYSIOLOGICALLY BASED MODELLING FOR CANCER DOSE RESPONSE ANALYSIS. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 79(1):28-37, (2004).

TORNERO-VELEZ, R., M. K. Ross, C. A. Granville, J. Laskey, J. P. Jones, D M. DeMarini, AND M V. Evans. METABOLISM AND MUTAGENICITY OF SOURCE WATER CONTAMINANTS 1, 3-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE. DRUG METABOLISM AND DISPOSITION 32(1):123-131, (2003).

Simmons, J E., M V. Evans, AND W K. Boyes. MOVING FROM EXTERNAL EXPOSURE CONCENTRATION TO INTERNAL DOSE: DURATION EXTRAPOLATION BASED ON PHYSIOLOGICALLY-BASED PHARMACOKINETIC-MODEL DERIVED ESTIMATES OF INTERNAL DOSE. Presented at DOD Risk Assessment Conference, Dayton, OH, April 26-30, 2004.

Mitchell, C T., M V. Evans, AND E M. Kenyon. USING IN VIVO GAS UPDATE STUDIES TO ESTIMATE METABOLIC RATE CONSTANTS FOR CCL CHEMICALS: 1,1-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.

Isaacs, K K., M V. Evans, AND T. R. Harris. VISUALIZATION-BASED ANALYSIS FOR A MIXED-INHIBITION BINARY PBPK MODEL: DETERMINATION OF INHIBITION MECHANISM. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 31(3):215-242, (2004).

2003

Boyes, W K., M Bercegeay, J S. Ali, Q T. Krantz, J K. McGee, M V. Evans, J. H. Raymer, P J. Bushnell, AND J E. Simmons. DOSE-BASED DURATION ADJUSTMENTS FOR THE EFFECTS OF INHALED TRICHOLOROETHYLENE ON RAT VISUAL FUNCTION. TOXICOLOGICAL SCIENCES 76:121-130, (2003).

Eklund, C R., M V. Evans, AND J E. Simmons. USE OF SENSITIVITY ANALYSIS ON A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR CHLOROFORM IN RATS TO DETERMINE AGE-RELATED TOXICITY. Presented at Society of Toxicology 42nd Annual Meeting, Salt Lake City, Utah, March 9-13, 2003.

2002

Evans, M V., W K. Boyes, J E. Simmons, D. Litton, AND M. R. Easterling. A COMPARISON OF HABER'S RULE AT DIFFERENT AGES USING A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR CHLOROFORM IN RATS. TOXICOLOGY. Elsevier Science Ltd, London, Uk, 176(1-2):11-23, (2001).