Office of Research and Development Publications

<< Previous

REIF, D., M. T. MARTIN, S. TAN, K. A. HOUCK, R. JUDSON, A. M. RICHARD, T. B. KNUDSEN, D. J. DIX, AND R. J. KAVLOCK. Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(12):2-8, (2010).

MARTIN, M. T., D. J. DIX, R. JUDSON, R. J. KAVLOCK, D. REIF, A. M. RICHARD, D. ROTROFF, S. ROMANOV, A. MEDVEDEV, N. POLTORATSKAYA, M. GAMBARIAN, M. MOESER, S. S. MAKAROV, AND K. A. HOUCK. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 23(3):578-90, (2010).

JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).

ROTROFF, D. M., B. A. WETMORE, D. J. DIX, S. S. FERGUSON, H. J. CLEWELL, K. A. HOUCK, E. L. LECLUYSE, M. E. ANDERSEN, R. JUDSON, C. M. SMITH, M. A. SOCHASKI, R. J. KAVLOCK, F. BOELLMANN, M. T. MARTIN, D. REIF, J. F. WAMBAUGH, AND R. S. THOMAS. Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening . TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 117(2):348-58, (2010).

JUDSON, R. Public Databases Supporting Computational Toxicology. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2):218-31, (2010).

SHAH, I. A. AND J. F. WAMBAUGH. Virtual Tissues in Toxicology. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2-4):314-328, (2010).

ROTROFF, D., A. L. BEAM, D. J. DIX, A. FARMER, K. M. FREEMAN, K. A. HOUCK, R. JUDSON, E. L. LECLUYSE, M. T. MARTIN, D. REIF, AND S. S. FERGUSON. Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 1(2-4):329-346, (2010).

KNIGHT, A. W., S. LITTLE, K. A. HOUCK, D. J. DIX, R. JUDSON, A. M. RICHARD, N. MCCARROLL, G. AKERMAN, C. YANG, L. BIRRELL, AND R. M. WALMSLEY. Evaluation of High-throughput Genotoxicity Assays Used in Profiling the US EPA ToxCast Chemicals. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 55(2):188-99, (2009).

Barrier, M., D. J. DIX, AND P. E. Mirkes. Inducible 70 kDa Heat Shock Proteins Protect Embryos from Teratogen-Induced Exencephaly: Analysis using Hspa1a/a1b Knockout Mice. BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 85(8):732-40, (2009).

RABINOWITZ, J. R., S. LITTLE, S. C. LAWS, AND M. GOLDSMITH. Molecular Modeling for Screening Environmental Chemicals for Estrogenicity: Use of the Toxicant-Target Approach . CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 22(9):1594-602, (2009).

Benfenati, E., R. Benigni, D. M. Demarini, C. Helma, D. Kirkland, T. M. Martin, P. Mazzatorta, G. Ouedraogo-Arras, A. M. RICHARD, B. Schilter, W. G. Schoonen, R. D. Snyder, AND C. Yang. Predictive Models for Carcinogenicity and Mutagenicity: Frameworks,State-of-the-Art, and Perspectives. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis Reviews. Taylor & Francis Group, London, Uk, 27(2):57-90, (2009).

HOUCK, K. A., D. J. DIX, R. JUDSON, R. J. KAVLOCK, J. YANG, AND E. L. BERG. Profiling Bioactivity of the ToxCast Chemical Library Using BioMAP Primary Human Cell Systems. Journal of Biomolecular Screening. SAGE Publications USA, Thousand Oaks, CA, 14(9):1054-1066, (2009).

MARTIN, M. T., R. JUDSON, D. REIF, R. J. KAVLOCK, AND D. J. DIX. Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database . ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 117(3):392-399, (2009).

MARTIN, M. T., E. MENDEZ, D. G. CORUM, R. JUDSON, R. J. KAVLOCK, D. ROTROFF, AND D. J. DIX. Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 110(1):181-90, (2009).

KAVLOCK, R. J., C. P. Austin, AND R. Tice. Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment. RISK ANALYSIS. Blackwell Publishing, Malden, MA, 29(4):485-7, (2009).

JUDSON, R., F. Elloumi, R. W. SETZER, Z. Li, AND I. A. SHAH. A Comparison of Machine Learning Algorithms for Chemical Toxicity Classification Using a Simulated Multi-Scale Data Model. BMC Bioinformatics. BioMed Central Ltd, London, Uk, (9):241, (2008).

JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, F. Elloumi, M. T. MARTIN, T. Cathey, T. R. Transue, R. SPENCER, AND M. WOLF. ACToR-Aggregated Computational Resource. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 233(1):7-13, (2008).

HOUCK, K. A. AND R. J. KAVLOCK. Understanding Mechanisms Toxicity: Insights from Drug Discovery Research. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 227(2):163-178, (2008).

DIX, D. J., K. A. HOUCK, M. MARTIN, A. M. RICHARD, R. W. SETZER, AND R. J. KAVLOCK. THE TOXCAST PROGRAM FOR PRIORITIZING TOXICITY TESTING OF ENVIRONMENTAL CHEMICALS . TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 95(1):5-12, (2007).