Office of Research and Development Publications

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This invited presentation will be given at the 4th Biannual Western Modeling Workshop in the Plenary session on Global model development, evaluation, and new source attribution tools. We describe the development and application of the hemispheric version of the CMAQ to examine th...

Children are often more vulnerable than adults to the effects of environmental contaminants found in their everyday environments. Their dynamic growth and unique interactions with the built, natural, and social environments may result in a greater susceptibility to chemical and n...

This is a presentation to be given at USAEE Annual Meeting in Houston, TX (Nov 12-15, 2017). The study explores the extent of the impact of uncertainties in upstream methane emissions from natural gas on the emission profile from the overall US energy system (consisting of the el...

Recordings of neural network activity in vitro are increasingly being used to assess the development of neural network activity and the effects of drugs, chemicals and disease states on neural network function. The high-content nature of the data derived from such recordings can ...

Volunteered geographic information (VGI) can be used to identify public valuation of ecosystem services in a defined geographic area using photos as a representation of lived experiences. This method can help researchers better survey and report on the values and preferences of s...

Physiologically-based pharmacokinetic (PBPK) models estimate chemical concentration changes in different body organs using a system of equations representing relevant biological processes and physicochemical properties. PBPK models are key to relating biochemical responses measur...

This presentation highlights Dr. Schifman's research work from the last two years of her NRC appt. here in NRMRL.

Comprehensive presentation to share and discuss transdisciplinary solutions to challenges faced in sustainable management of urban water. Present research on urban water challenges and solutions, followed by an open panel discussion about overcoming multiple challenges by integra...

Screening methods for detecting potential endocrine disrupting chemicals rely chiefly on transactivation assays targeting nuclear receptors such as the estrogen (ER) and androgen receptors (AR). These assays are predominately human-based; yet environmental exposure can affect div...

A focus for resource management, conservation planning, and environmental decision analysis has been mapping and quantifying biodiversity and ecosystem services. The challenge has been to integrate ecology with economics to better understand the effects of human policies and acti...

Biodiversity is crucial for the functioning of ecosystems and the products and services from which we transform natural assets of the Earth for human survival, security, and well-being. The ability to assess, report, map, and forecast the life support functions of ecosystems is a...

Biodiversity is crucial for the functioning of ecosystems and the products and services from which we transform natural assets of the Earth for human survival, security, and well-being. The ability to assess, report, map, and forecast the life support functions of ecosystems is a...

Nearshore conditions drive phenomena like harmful algal blooms (HABs), and the nearshore and coastal margin are the parts of the Great Lakes most used by humans. To assess conditions, optimize monitoring, and evaluate management options, a model of nearshore nutrient transport an...

The predominant focus of Tox21 collaboration has been on developing and applying high-throughput in vitro screening to hazard identification and dose-response. To remain relevant, the interagency collaboration must broaden its focus to developing new predictive toxicology testing...

Presentation at Scientific Advisory Committee On Alternative Toxicological Methods (SACATM) Sep 2017

In the Community Multiscale Air Quality (CMAQv5.2) model, we have implemented two algorithms for lightning NO production; one algorithm is based on the hourly observed cloud-to-ground lightning strike data from National Lightning Detection Network (NLDN) to replace the previous m...

A quantitative adverse outcome pathway (qAOP) consists of interrelated computational models that together describe the mechanistic biology linking a toxicant-induced, molecular-level initiating event (MIE) with an adverse outcome at the level of individuals or populations. A qAOP...

Exposures to chemical and non-chemical stressors from children&rsquo;s environments during early development may contribute to differences in their health and well-being outcomes. Children from American Indian tribes may have a disproportionate burden of these stressors from thei...

Presentation on alternative water reuse.

Presentation to be given at AWWA ACE 2017 in Philadelphia, 6/12/17.

Choosing where to sample for aquatic invasive species (AIS) is a daunting challenge in the Laurentian Great Lakes. Management resources are finite hence it is important that monitoring efforts concentrate on those sites with the highest risk of introduction based on transparent c...

Engineered nanomaterials (ENMs) represent a new regulatory challenge because of their unique properties and their potential to interact with ecological organisms at various developmental stages, in numerous environmental compartments. Traditional toxicity tests have proven to be...

This presentation provides an overview of the status of USEPA collaborative activities as part of the CRESSIDA effort in the Western Balkans.

Cumulative risk assessment (CRA) methods, which evaluate the risk of multiple adverse outcomes (AOs) from multiple chemicals, promote the use of a conceptual site model (CSM) to integrate risk from relevant stressors. The Adverse Outcome Pathway (AOP) framework can inform these r...

Out-of-hospital sudden unexpected deaths (OHSUD) are natural deaths that occur without obvious underlying causes and account for nearly 1 in 6 deaths in the United States. Ambient air pollution is known to be causally related to overall mortality, therefore, we hypothesized that ...