Science Inventory

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Houck, K., C. LaLone, A. Bone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarov. A Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SLAS meeting). Presented at 2017 SLAS meeting, Washington, DC, February 04 - 08, 2017. https://doi.org/10.23645/epacomptox.5181265

LaLone, C., G. Ankley, S. Belanger, M. Embry, G. Hodges, D. Knapen, S. Munn, E. Perkins, M. Rudd, Dan Villeneuve, M. Whelan, C. Willett, X. Zhang, AND M. Hecker. Advancing the Adverse Outcome Pathway Framework - an International Horizon Scanning Approach. SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY JOURNAL. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(6):1411-1421, (2017).

Mortensen, H., M. Pittman, C. LaLone, AND S. Edwards. Defining a Computational Framework for the Assessment of Taxonomic Applicability. SOT, Baltimore, MD, March 12 - 16, 2017.

Martinovic-Weigelt, D., A. Mehinto, G. Ankley, J. Berninger, Tim Collette, J. Davis, N. Denslow, E. Durhan, E. Eid, D. Ekman, K. Jensen, M. Kahl, C. LaLone, Q. Teng, AND Dan Villeneuve. Derivation and evaluation of putative adverse outcome pathways for the effects of cyclooxygenase inhibitors on reproductive processes in female fish. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 156(2):344-361, (2017).

Houck, K., C. LaLone, R. Judson, M. Martin, Dan Villeneuve, G. Ankley, A. Medvedev, AND S. Markarorav. Evaluation of an In Vitro Multi-Receptor and Multi-Species Assay for Potential Endocrine Disruptor Targets (SOT). Presented at SOT National Meeting, Baltimore, MD, March 12 - 16, 2017.

Fay, K., Dan Villeneuve, C. LaLone, Y. Song, K. Tollefsen, AND G. Ankley. Practical approaches to adverse outcome pathway development and weight‐of‐evidence evaluation as illustrated by ecotoxicological case studies . SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY JOURNAL. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(6):1429–1449, (2017).

Tal, T., C. Kilty, A. Smith, C. LaLone, B. Kennedy, A. Tennant, C. McCollum, M. Bondesson, T. Knudsen, S. Padilla, AND N. Kleinstreuer. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 70:70-81, (2017).

Elias, M., G. Ankley, M. Barron, C. Bergeron, R. Burgess, S. Cormier, R. Erickson, M. Etterson, D. Hoff, C. LaLone, Dave Mount, G. Suter, Dan Villeneuve, K. Ho, M. Cantwell, M. Willming, Sandy Raimondo, L. Cruz, A. Jarvis, D. Eignor, J. Justice, M. Lewis, G. Thursby, AND K. Gallagher. Update on US EPA’s Revision to the 1985 Guidelines for Deriving Aquatic Life Criteria. Society of Environmental Toxicology and Chemistry, Minneapolis, MN, November 12 - 16, 2017.

LaLone, C. Using an adverse outcome pathway network to describe the weight of evidence linking nicotinic acetylcholine receptor activation to honey bee colony failure. American Chemical Society National Meeting, Washington, DC, August 20 - 24, 2017.

LaLone, C., Dan Villeneuve, J. Wu-Smart, R. Milsk, K. Sappington, K. Garber, J. Housenger, AND G. Ankley. Weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 584:751–775, (2017).

LaLone, C. AND M. Hecker. Advancing the adverse outcome pathway framework and its applications through a global horizon scanning exercise. To be Presented at Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.

Villeneuve, Dan, G. Ankley, C. LaLone, Dave Mount, Joe Tietge, AND D. Hoff. Application of adverse outcome pathway-based tools to ambient water quality criteria development. SETAC North America, Orlando, FL, November 06 - 10, 2016.

LaLone, C., G. Ankley, T. Tal, AND Dan Villeneuve. Assessing cross species conservation of ToxCast Assay targets using Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS). To be Presented at Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.

LaLone, C., Dan Villeneuve, AND G. Ankley. Cross-species evaluation of molecular target sequence and structural conservation as a line of evidence for identification of susceptible taxa to inform derivation of aquatic life criteria. SETAC North America, Orlando, FL, November 06 - 10, 2016.

LaLone, C. Cross-species extrapolation of toxicity information using the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool. International Fresenius: Endocrine Disruptors, Bonn, GERMANY, November 15 - 16, 2016.

Ankley, G., C. LaLone, E. Gray, Dan Villeneuve, AND M. Hornung. Evaluation of the scientific underpinnings for identifying estrogenic chemicals in non-mammalian taxa using mammalian test systems. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(11):2806-2816, (2016).

Willming, M., C. LaLone, AND M. Barron. Improving toxicity extrapolation using molecular sequence similarity: A case study of pyrethroids and the sodium ion channel. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.

Pittman, M., C. LaLone, Dan Villeneuve, AND S. Edwards. Informatics approaches in the Biological Characterization of Adverse Outcome Pathways. GEMS Fall Meeting, RTP, NC, November 09, 2016.

Cavallin, J., K. Jensen, M. Kahl, Dan Villeneuve, K. Lee, A. Schroeder, J. Mayasich, E. Eid, K. Nelson, R. Milsk, B. Blackwell, J. Berninger, C. LaLone, C. Blanksma, T. Jicha, C. Elonen, R. Johnson, AND G. Ankley. Pathway-based approaches for assessment of real-time exposure to an estrogenic wastewater treatment plant effluent on fathead minnow reproduction. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(3):702-716, (2016).

Berninger, J., C. LaLone, Dan Villeneuve, AND G. Ankley. Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large scale mammalian pharmacological dataset. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(4):1007-1020, (2015).

LaLone, C., Dan Villeneuve, H. Helgen, D. Lane, S. Walata, K. Nelson, S. Robinson, J. Swintek, AND G. Ankley. Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A web-based tool for addressing the challenges of cross-species extrapolation of chemical toxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 153(2):228-245, (2016).

Willming, M., C. LaLone, Sandy Raimondo, AND M. Barron. State-of-Science Approaches to Determine Sensitive Taxa for Water Quality Criteria Derivation. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.

LaLone, C., R. Milsk, Dan Villeneuve, K. Garber, K. Sappington, J. Housenger, AND G. Ankley. Weight-of-evidence evaluation of an adverse outcome pathway network linking activation of the nicotinic acetylcholine receptor in bees to colony loss. SETAC North America, Orlando, FL, November 06 - 10, 2016.

LaLone, C., M. Hornung, E. Gray, AND G. Ankley. Application of a framework for extrapolating chemical effects across species in pathways controlled by estrogen receptor-á. SETAC North America, Salt Lake City, UT, November 01 - 05, 2015.

Davis, J., D. Ekman, D. Skelton, C. LaLone, G. Ankley, J. Cavallin, Dan Villeneuve, AND Tim Collette. Applying high resolution mass spectrometry and network analysis to assess exposure to a novel androgen, spironolactone, on metabolic pathways in fish. SETAC North America 36th Annual Meeting, Salt Lake City, UT, November 01 - 06, 2015.