Science Inventory

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The multivariate AMBI (M-AMBI) is an extension of the AZTI Marine Biotic Index (AMBI) that has been used extensively in Europe, but not in the United States. In a previous study, we adapted AMBI for use in US coastal waters (US AMBI), but saw biases in salinity and score distribu...

The Model for Prediction Across Scales &ndash; Atmosphere (MPAS-A) has been modified to allow four-dimensional data assimilation (FDDA) by the nudging of temperature, humidity, and wind toward target values predefined on the MPAS-A computational mesh. The addition of nudging allo...

In estuaries, land-surface and tidal elevation conspire to influence the amount of salt-water inundation in a specific location, ultimately affecting the distribution of estuary vegetation. Plants vary in their tolerances to salinity and inundation. Understanding even small chang...

Atmospheric models that accurately describe the fate and transport of trace species for the right reasons aid in the development of effective air-quality management strategies that safeguard human health. Controllable emissions facilitate the formation of biogenic secondary organ...

Recent studies showed that the circulating stress hormones, epinephrine and corticosterone/cortisol, are involved in mediating ozone-induced pulmonary effects through the activation of the sympathetic-adrenal-medullary (SAM) and hypothalamus-pituitary-adrenal (HPA) axes. Hence, w...

Nanotechnology has significant economic, health, and environmental benefits, including renewable energy and innovative environmental solutions. Manufactured nanoparticles have been incorporated into new materials and products because of their novel or enhanced properties. These v...

This work presents the results of an international interlaboratory comparison on ex situ passive sampling in sediments. The main objectives were to map the state of the science in passively sampling sediments, identify sources of variability, provide recommendations and practica...

The US EPA is developing more cost effective and efficient ways to evaluate chemical safety using high throughput and computationally based testing strategies. An important component of this approach is the ability to translate chemical effects on fundamental biological processes...

The US EPA is developing more cost effective and efficient ways to evaluate chemical safety using high throughput and computationally based testing strategies. An important component of this approach is the ability to translate chemical effects on fundamental biological processes...

Chemicals induce liver cancer in rodents through well characterized adverse outcome pathways (AOPs). We hypothesized that measurement of molecular initiating events (MIEs) and downstream key events (KEs) in liver cancer AOPs in short-term assays will allow early identification of...

Citizen science provides quantitative results to support environmental health assessments, but standardized approaches do not currently exist to translate findings into actionable solutions. The emergence of low-cost portable sensor technologies and proliferation of publicly avai...

Over time, risk assessment has shifted from establishing relationships between exposure to a single chemical and a resulting adverse health outcome, to evaluating multiple chemicals and disease outcomes simultaneously. As a result, there is an increasing need to better understand...

The aggregation and long-term (25 d) sedimentation behaviors of reduced graphene oxide (RGO) and its three successively self-assembled nanohybrids with magnetite (Fe3O4) and zerovalent silver (Ag0) nanoparticles were investigated. The aggregation behaviors of the nanomaterials in...

Many cities are experiencing long-term declines in population and economic activity. As a result, frameworks for urban sustainability need to address the unique challenges and opportunities of such shrinking cities. Shrinking, particularly in the U.S., has led to extensive vacant...

There currently are a wide variety of approaches emerging to adjust air sensor data, either on the device or more commonly, on a manufacturer's server or cloud. The goal of these adjustments are to correct for measurement artifacts and produce more accurate values. However, most ...

It is often of interest to model the incidence and duration of threshold exceedance events for an environmental variable over a set of monitoring locations. Such data arrive over continuous time and can be considered as observations of a two-state process yielding, sequentially, ...

Within the field of chemical safety assessment, there is a desire to replace costly whole organism testing with more efficient and cost-effective alternatives based on in vitro test systems. Disruption of thyroid hormone signaling via inhibition of enzymes called deiodinases is o...

Urban water systems consist of natural and engineered flows of water interacting in complex ways. System complexity can be understood via mass conservative models that account for the interrelationships among all major flows and storages. We have developed a generic urban water s...

The Maximum Cumulative Ratio (MCR) quantifies the degree to which a single chemical drives the cumulative risk of an individual exposed to multiple chemicals. Phthalates are a class of chemicals with ubiquitous exposures in the general population that have the potential to cause ...

Epiphytes on seagrass (Zostera marina) growing in the lower intertidal were examined along an estuarine gradient within Yaquina Bay, Oregon over a period of 4 years. The Yaquina Estuary receives high levels of nutrients from the watershed during the wet season and from the ocean...

Predictive testing to characterise substances for their skin sensitisation potential has historically been based on animal models such as the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximisation Test (GPMT). In recent years, EU regulations, have provided a strong incenti...

Although metal(loid) bioaccessibility of ambient particulate matter, with an aerodynamic diameter of <10 μm (PM10), has recently received increasing attention, limited research exists into standardising in-vitro methodologies using simulated lung fluid (SLF). Contradictions exist...

The ongoing evolution of mixing models has resulted in a confusing array of software tools that differ in terms of data inputs, model assumptions, and associated analytic products. Here we introduce MixSIAR, an inclusive, rich, and flexible open-source Bayesian stable isotope mix...

A newly developed integrated cell culture reverse transcriptase quantitative PCR (ICC-RTqPCR) method and its applicability in UV disinfection studies is described. This method utilizes a singular cell culture system coupled with four RTqPCR assays to detect infectious serotypes t...

A vast amount of future climate scenario datasets, created by climate models such as general circulation models (GCMs), have been used in conjunction with watershed models to project future climate variability impact on hydrological processes and water quality. However, these low...