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Introduction: Exposure to PM2.5 air pollution and neighborhood-level sociodemographic characteristics are associated with cardiovascular disease and possibly diabetes. However, the joint effect of sociodemographics and PM2.5 on these outcomes is uncertain. Methods: We examined wh...

After repeated daily ozone exposure for more than 2 days, rodents demonstrate adaptation/acclimatization from initial lung injury, inflammation and functional alterations. The mechanisms of adaptation to ozone, other pollutants, or non-chemical stressors are not well known. We h...

The following abstract is for a presentation at the 2019 Air and Waste Management Association’s Air Quality Measurements and Methods Conference in Durham NC, April 2-4 2019. Abstract: Industrial facilities have the potential to emit volatile organic compounds (VOCs), hazardous ...

A non-targeted analysis workflow was applied to analyze exhaled breath samples collected from firefighters pre- and post-structural fire suppression. Breath samples from firefighters functioning in attack and search positions were examined for target and non-target compounds in a...

Oxidative stress and release of pro-inflammatory mediators are well established signaling events following inhaled chemical exposure; however, our understanding of the distinct cellular and molecular pathways involved in inhalation toxicity remain limited due to studies centered ...

Implantation is a sensitive window in reproductive development during which disruptions may increase the risk of adverse pregnancy outcomes including intrauterine growth restriction. Ozone exposure during implantation in rats reduces fetal weight near the end of gestation, potent...

Several recent studies from our lab and others have demonstrated widespread metabolic effects following an acute ozone exposure. Although these effects are similar to those induced by the fight-or-flight response involving adrenal-derived stress hormones, little data are availab...

A method for the determination of polychlorinated biphenyls (PCBs) in caulk was developed. This method was evaluated by application to a combination of 47 samples of caulk, glazing materials, and including quality control samples, from four schools in the northeastern area of the...

By one estimate, reservoirs are the fourth largest anthropogenic methane (CH4) source in the U.S., with emissions equivalent to about half of those from all U.S. landfills. Reservoir emission estimates are poorly constrained, however, due to large variation in emission rates amo...

Particulate matter mass (PM), trace gaseous pollutants, and select volatile organic compounds (VOCs) with meteorological variables were measured in Logan, Utah (Cache Valley) for > 4-weeks during winter 2017 as part of the Utah Winter Fine Particle Study (UWFPS). Higher PM levels...

Peri-implantation ozone exposure induces fetal growth restriction in the rat. However, the influence of placental health in mediating the impact of ozone on fetal size and neurodevelopment has not been studied. Therefore, we examined placental metabolic adaptations and alteration...

An estimated 3.5-million people die every year from air pollution-induced cardiovascular disease (API-CVD); however, while in vivo data has demonstrated associations between induced CVD and systemic oxidative stress, the causative molecular mechanisms driving API-CVD are still po...

For decades, the focus of drinking water providers has been on fecal pathogens like E. coli, Giardia, and Cryptosporidium. In recent years, drinking water professionals and building operators have begun to recognize the importance of so-called opportunistic pathogens like Legione...

Background More intense and longer&#8208;lasting heat events are expected in the United States as a consequence of climate change. This study aimed to project the potential changes in maternal heat exposure during early pregnancy (3&ndash;8 weeks post conception) and the associat...

The goals of this workshop are to introduce individuals to protocols for collecting continuous sensor data using low budget fixed arrays. In addition, to introduce individuals to R tools for working with continuous vertical profile data.

Exposure is a key component of evaluating the risks posed by anthropogenic chemicals. Exposure is the degree or contact between a chemical and human and ecological target populations. EPA&rsquo;s Exposure Forecaster (ExpoCast) project is charged with collecting exposure-relevant ...

Exposure to wildland fire-related particulate matter (PM) causes adverse health outcomes. However, the impacts of specific biomass sources remain unclear. The purpose of this study was to investigate cardiopulmonary responses in rats following exposure to PM extracts collected fr...

REal TIme Geospatial Data Viewer (RETIGO) is a free, web-based application that can be used to explore environmental data that has been collected either stationary or in motion (e.g., air quality sensors added to a bike). The web application was updated in February 2019 with new ...

Sea-level rise (SLR) is not just a future trend; it is occurring now in most coastal regions across the globe. It thus impacts not only long-range planning in coastal environments, but also emergency preparedness. Its inevitability and irreversibility on long time scales, in addi...

This report describes the state of the science with respect to total Nr deposition budgets in the United States and the research needed to improve these budgets from both a measurement and modeling perspective. The document is intended to serve as a roadmap for research activiti...

Decision makers at all levels of government face challenges in protecting human health and the environment &ndash; in particular, gaining access to the latest scientific findings that can bolster the foundation of those decisions. EPA&rsquo;s Office of Research and Development (O...

5-hydroxymethylfurfuryl (HMF) is one of the common but essential platform chemicals derived from carbohydrates and can be further upgraded to a variety of useful entities such as 2,5-furandicarboxylic acid (FDCA).1 FDCA has widely used the substance in the production of bio-based...

Global change influences biogeochemical cycles within and between environmental compartments (i.e., the cryosphere, terrestrial and aquatic ecosystems, and the atmosphere). A major effect of global change on carbon cycling is altered exposure of natural organic matter (NOM) to so...

Air pollution has become an adverse environmental problem in China, resulting in serious public health impacts. This study advanced and applied the CMAQ adjoint model to quantitatively assess the source-receptor relationships between surface ozone (O3) changes over different rece...

CMAQ is a comprehensive atmospheric modeling system. This invited presentation overviews the development history and recent enhancements to the modeling system in context of its use for the following emerging air pollution issues: (1)Examination of U.S. air pollution in context o...