Science Inventory

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Houck, K., A. Karmaus, A. Richard, AND J. Franzosa. Heavy Metals in ToxCast: Relevance to Food Safety (SOT). Presented at SOT, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5084224

Palmer, J., T. Knudsen, L. Egnash, P. Kothiya, K. Houck, AND B. Donley. Human Pluripotent Stem Cell-Based Assay Predicts Developmental Toxicity Potential of ToxCast Chemicals (ACT meeting). Presented at American College of Toxicology, Baltimore, MD, November 06 - 09, 2016. https://doi.org/10.23645/epacomptox.5181325

Simmons, Steve, Eric Watt, K. Paul-Friedman, K. Houck, R. Judson, M. Hornung, AND K. Crofton. Identification of Chemical Features Linked to Thyroperoxidase Inhibition (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155789

Franzosa, J., J. Liu, R. Thomas, J. Wambaugh, K. Houck, AND I. Shah. Prediction of in vivo hepatotoxicity effects using in vitro transcriptomics data (SOT). Presented at SOT annual meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176498

Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).

Paul-Friedman, K., Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck, AND Steven O. Simmons. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):160-180, (2016).

Knudsen, T., P. Kothiya, AND K. Houck. Toxcast Profiling in a Human Stem Cell Assay for Developmental Toxicity (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155729

Padilla, S., K. Houck, S. Mosher, R. Judson, AND M. Martin. Toxicity Screening of a Subset of the ToxCast Chemical Library Using a Zebrafish Developmental Assay: Comparison of Methods. Fish and Amphibian Embryos as Alternative Models in Toxicology and Teratology, Paris, FRANCE, December 01 - 02, 2016.

Shah, I., Woodrow Setzer, J. Jack, K. Houck, R. Judson, T. Knudsen, J. Liu, M. Martin, D. Reif, Ann M. Richard, Russell S. Thomas, K. Crofton, David J. Dix, AND Robert J. Kavlock. Using ToxCast data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(7):910-919, (2016).

Kligerman, A., R. Young, L. Stankowski, K. Pant, T. Lawlor, M. Aardema, AND K. Houck. An Evaluation of 25 Selected ToxCast Chemicals in Medium-Throughput Assays to Detect Genotoxicity. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. John Wiley & Sons, Inc, Hoboken, NJ, 56(5):468-476, (2015).

Richter, A., J. Brown, B. Bharti, A. Wang, S. Gangwal, K. Houck, E. Hubal, V. Paunov, S. Stoyanov, AND O. Velev. An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core. Nature Nanotechnology. Nature Publishing Group, London, Uk, 10(9):817-823, (2015).

Houck, K. Analysis of Chemical Bioactivity through In Vitro Profiling using ToxCast and Tox21 High-Throughput Screening (China tox. conf. TATT). Presented at Annual Conference on Toxicological Alternatives and Translational Toxicology, Xi'An, CHINA, July 26 - 29, 2015. https://doi.org/10.23645/epacomptox.5080027

Schroeder, A., G. Ankley, B. Blackwell, K. Houck, AND Dan Villeneuve. Characterizing the bioactivity of complex environmental samples using high throughput toxicology. SETAC, North America, Salt Lake City, UT, November 01 - 05, 2015.

Knudsen, T. B., A. M. Richard, P. G. Kothiya, R. S. Judson, K. A. Houck, K. C. Crofton, R. S. Thomas, S. Little, E. S. Hunter, N. C. Baker, C. K. M. Leung, J. Palmer, A. Smith, M. Colwell, P. West, R. Burrier, AND L. Egnash. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT). Presented at Society of Toxicology, San Diego, CA, March 21 - 26, 2015. https://doi.org/10.23645/epacomptox.5178703

Franzosa, J., J. Jack, P. Kothiya, D. Filer, J. Liu, J. Bonzo, S. Ferguson, I. Shah, A. Richard, R. Thomas, J. Wambaugh, AND K. Houck. Evaluation of In Vitro Biotransformation Using HepaRG Cells to Improve High-Throughput Chemical Hazard Prediction: A Toxicogenomics Analysis (SOT). Presented at 2015 Annual SOT Meeting, San Diego, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178868

Patlewicz, G., K. Houck, R. Judson, A. Richard, I. Shah, AND A. Williams. Exploiting enhanced non-testing approaches to meet the needs for sustainable chemistry. Presented at ACS Meeting, Boston, MA, August 16 - 20, 2015. https://doi.org/10.23645/epacomptox.5077792

Connors, K., D. Filer, N. Sipes, R. Judson, K. Houck, AND M. Martin. High content screening of ToxCast compounds using Vala Sciences’ complex cell culturing systems (SOT). Presented at SOT Annual Meeting, San Deigo, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178847

Wetmore, B., John F. Wambaugh, B. Allen, S. Ferguson, M. Sochaski, R. Woodrow Setzer, Keith A. Houck, C. Strope, K. Cantwell, Richard S. Judson, E. LeCluyse, H. Clewell III, Russell S. Thomas, AND M. Andersen. Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, , 1-57, (2015).

Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, Woodrow Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, :1-42, (2015).

Godwin, H., C. Nameth, D. Avery, L. Bergeson, D. Bernard, E. Beryt, W. Boyes, S. Brown, A. Clippinger, Y. Cohen, C. Olgilvie Hendren, P. Holden, K. Houck, A. Kane, F. Klaessig, T. Kodas, R. Landsiedel, I. Lynch, T. Malloy, M. Miller, J. Mueller, G. Oberdorester, R. Pleus, P. Sayre, V. Stone, K. Sullivan, J. Tentschert, P. Wallis, AND A. Nel. Nanomaterial Categorization for Assessing Risk Potential to Faciliate Regulatory Decision-Making. ACS Nano. American Chemical Society, Washington, DC, 9(4):3409-3417, (2015).

Blackwell, B., A. Schroeder, J. Berninger, J. Cavallin, K. Lee, M. Lee, K. Jensen, M. Kahl, Z. Jorgenson, K. Houck, R. Judson, Dan Villeneuve, AND G. Ankley. Novel approaches to effects-based monitoring: 21st century tools for bio-effects prediction and surveillance. SETAC Europe, Barcelona, SPAIN, May 03 - 07, 2015.

Houck, K. Phenotypic Screening of Primary Human Cell Culture Systems to Identify Potential for Compound Toxicity (CHI Phenotypic Screening). Presented at Cambridge Healthtech Institute’s Phenotypic Screening, San Diego, CA, January 26 - 27, 2015. https://doi.org/10.23645/epacomptox.5080015

Houck, K. Presentations: In vitro Evaluation of Steroidogenesis: H295R Assay and EDSP overview( 11th annual US-Japan Bilateral Meeting on Endocrine Disruption). 11th annual US-Japan Bilateral Meeting on Endocrine Disruption, Washington, DC, September 15 - 16, 2015. https://doi.org/10.23645/epacomptox.5080036

Franzosa, J., D. Mahapatra, K. Connors, R. Huang, M. Xia, R. Thomas, S. Kullman, AND K. Houck. Quantitative High-Throughput Screening and Orthogonal Assays to Identify Modulators of the Vitamin D Receptor (SETAC). Presented at SETAC, Salt Lake City, UT, November 01 - 05, 2015. https://doi.org/10.23645/epacomptox.5189329

Houck, K. The ToxCast Chemical Prioritization Program at the US EPA (UCLA Molecular Toxicology Program). Presented at UCLA Molecular Toxicology Program, Los Angeles, CA, November 12, 2015. https://doi.org/10.23645/epacomptox.5071285