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Background: Observational epidemiologic studies provide critical data for the evaluation of the potential effects of environmental, occupational and behavioural exposures on human health. Systematic reviews of these studies play a key role in informing policy and practice. System...

High-throughput transcriptomics (HTTr) is increasingly being used to identify molecular targets of chemicals that can be linked to adverse outcomes. Cell proliferation is an important key event in chemical carcinogenesis. Here, we describe the construction and characterization of...

Coastal areas are important places to live, work, play, and more. They are areas with high social and economic value, but also with considerable commercial and private uses which lead to conflicts, disproportionately affected communities, and complex environmental decision making...

Identification of potential pathogens that present risks to human health in recreational waters is necessary to advance in-depth water quality assessments. Despite the application of PCR techniques for environmental pathogen detection, only limited information is usually availabl...

An &lsquo;organon&rsquo; is a thought instrument or system of logic that unifies a body of scientific principles. The Adaptation Organon (AO) is an interactive, web-based instrument for considering climate change and other environmental information to inform adaption and improve ...

VELMA - Visualizing Ecosystem Land Management Assessments, is a framework for creating ecohydrological models.&nbsp; VELMA was designed to work in a variety of watersheds but increasing urban areas have created challenges for creating accurate models.&nbsp; We have added a number...

Over the last 10 years the EPA has been conducting research to better quantify the magnitude of greenhouse gas emissions from US reservoirs. &nbsp; In 2021 reservoirs were included in the Inventory of US Greenhouse Gas Emissions and Sinks for the first time and currently estimate...

Background and Purpose: Adrenergic receptors (AR) are the most extensive therapeutically manipulated drug receptors in the treatment of respiratory diseases, such as asthma and chronic obstructive pulmonary disease. The airways are densely innervated by AR, which are cellular rec...

The EPA Office of Research and Development&rsquo;s Next Generation Emission Measurement (NGEM) program focuses on researching the deployment of lower-cost air sensors near known emissions sources. The air quality measurements collected with these sensors can be used to indicate t...

An in situ oil burn plume was characterized to provide a unique aerial data set for development and calibration of near-source dispersion models. Seven in situ burns (ISBs) were conducted on a subset of a 1 ha artificial pond. The Alaska North Slope crude oil burn plume was sampl...

Several related research efforts are in-progress in the US EPA to inform a large(r) hazard and dose-response landscape for per- and polyfluoroalkyl substances (PFAS); such data may be critical to informing data-poor mixture PFAS. The expressed objective is to identify dose-respon...

While SWMM has arguably played a pivotal role in pollution control in collection systems since its introduction, traditional applications using the model have been relatively static. They typically involve calibrating and validating SWMM models with data collected and curated for...

This is a presentation abstract for proposed session, ID 141, Advances in New Approach Methods for Thyroid Toxicity Testing, for the SOT 2024 Annual Meeting.&nbsp; Abstract: There is significant regulatory need to evaluate chemicals that may disrupt the thyroid endocrine system. ...

Chemical safety assessment begins with defining the lowest level of chemical that alters one or more measured endpoints. This critical effect level, along with factors to account for uncertainty, is used to derive limits for human exposure. In the absence of data regarding the sp...

This is a broad overview presentation covering CEMM's ambient and near-source air measurement research for an international audience. The presentation includes content related to Federal Reference Methods (FRMs) and Federal Equivalent Methods (FEMs) for the NAAQS, air sensor tech...

This is the PowerPoint slide deck for the Science to Achieve Results (STAR) &ldquo;Air Quality Information: Making Sense of Air Pollution Data to Inform Decisions in Underserved Communities Overburdened by Air Pollution&rdquo; Funding Opportunity Informational Webinar that will b...

In the United States, the Clean Air Act requires the Environmental Protection Agency (EPA) to establish National Ambient Air Quality Standards (NAAQS) and to monitor six common air pollutants. For NAAQS compliance, air quality instruments must adhere to stringent sampling, siting...

Taxonomic data are the foundation of bioassessment and much basic and applied research. Difficulty in morphological species identification, evolving and varying taxon concepts, and nomenclatural changes can lead to significant inconsistencies in taxonomic datasets across analysts...

Lead (Pb) and arsenic (As) contamination of soils is widespread in the United States and is an important source of exposure in young children. Early life exposure to metal(loid) contaminants has serious and long-lasting effects on health, making mitigation a critical public healt...

In the US there are over 20,000 abandoned hardrock mines that may present risks to human health or the environment from long-term exposure to harmful substances. One site is the Formosa mine Superfund site located in Oregon, US. The site lacks plant cover due to phytotoxic tailin...

Communities across the United States and particularly in the Midwest continue to grapple with the complications associated with aging infrastructure. This includes the presence of lead (Pb)-bearing plumbing components such as lead service lines (LSLs), downstream galvanized iron ...

A PowerPoint presentation created by the National Program Manager for Regional Laboratories to present to the Association of Public Health Laboratories.

In-situ burning (ISB) is the controlled burning of oil spilled from a vessel or pipeline. There were multiple ISB events after the Deepwater Horizon oil spill on April 20, 2010, including 410 ISBs conducted by the Coast Guard [1]. Proponents of ISB suggest that it offers a rapid ...

Per- and polyfluoroalkyl substances (PFASs) have been detected in an array of environmental media due to their ubiquitous use in industrial and consumer products as well as potential release from fluorochemical manufacturing facilities. During their manufacture, many fluorotelome...

The Regional Monitoring Networks (RMNs) are a collaborative, volunteer effort to collect comparable long-term monitoring data at targeted sites nationwide to detect changes over time. Six Northeast states have participated in the stream RMN since it was first piloted in the North...