Science Inventory

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Federal agencies are increasing efforts to provide support to local communities for climate adaptation and hazard resilience. This involves engaging communities using approaches to understand and address problems holistically, particularly where equity and environmental justice a...

SOT 2024 Abstract Background and Purpose: The use of in vitro systems to model the effects of inhalation exposures has focused on using differentiated primary human bronchial epithelial cell (dpHBEC) cultures as they recapitulate key features of the airway epithelium in vivo.&nbs...

Seagrass beds&nbsp;play a critical role in biodiversity maintenance, serving as nursery habitats for fisheries, and aiding in carbon and sediment sequestration in the ecosystem. These habitats receive dissolved and particulate material inputs, like nutrients and heavy metals, aff...

Many factors, including microbiome structure and activity in the drinking water distribution system (DWDS), affect the colonization potential of opportunistic pathogens. The present study aims to describe the dynamics of active bacterial communities in DWDS and identify the facto...

Computational fluid dynamics simulations are used to model the velocity field and the transport of a passive scalar within a micro-scale chamber used to measure diffusional transport through various building materials.&nbsp; Comparisons of solutions obtained using a steady, lamin...

Causal structural models are used to capture knowledge of a problem domain through framing potential events as random variables and connections as causal arcs. Moreover, the properties of causal structural models foster additional insights on causal and inferential interactions a...

Framing ecological restoration and monitoring goals from a human benefits perspective (i.e., ecosystem services) can help inform restoration planners, surrounding communities, and relevant stakeholders about the direct benefits they may obtain from a specific restoration project....

Invited presentation to 2024 Winter ToxForum meeting.&nbsp;&nbsp; EPA&rsquo;s Office of Research and Development (ORD) is advancing their portfolio of human health toxicity assessment products to draw on the range of available toxicity data to inform the myriad public health deci...

This presentation is Part 2 consumption-based GHG emissions inventory for the state of Maine. This presentation is focused on results of the study, interpretation, and identifying opportunities for further exploration.

The economic and methodological efficiencies of environmental DNA (eDNA) based survey approaches provide an unprecedented opportunity to assess and monitor aquatic environments. However, instances of inadequate communication from the scientific community about confidence levels, ...

Source control of mine drainage and leachate from mining wastes is ideal, but there is limited use of control methods aside from removal of wastes to repositories or capping wastes in situ. In some locations, neither removal nor capping is possible; thus, there is renewed interes...

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Data visualization tools that are quick and easy to use, require no coding skills, and can be used with any type of sensor are in high demand.&nbsp; In addition to visualizing their own data, users often wish to compare the data they collect with other nearby data sources such as...

Wastewater is a source for many contaminants of emerging concern (CECs) and surface waters receiving wastewater discharge often serve as source water for downstream drinking water treatment plants. Non-targeted analysis and suspect screening methods were used to characterize chem...

Thyroid hormones (TH) are highly iodinated molecules that regulate many aspects of mammalian physiology and are essential for normal growth and development. Deiodinases (DIO) are a family of three metabolizing enzymes (DIO1, DIO2, DIO3) by activating or deactivating TH action. Th...

An objective of federal, state, and local environmental management programs is to provide citizens with clean waters and the benefits associated with them. Communicating the importance of clean water to the public is often thought to help promote changes to behaviors and actions ...

The San Juan Bay Estuary (SJBE) is an interconnected system of streams, bays, lagoons, and canals located in a highly urbanized area in San Juan, Puerto Rico. Due to the rapid rate of urbanization, some communities across the SJBE have limited access to or are impacted by failure...

INTRODUCTION: Coccidioidomycosis is an emerging fungal infection caused by inhalation of airborne spores of the Coccidioides genus. While Coccidioides immitis has been detected in soils across California, successful recovery of C. immitis from air samples has so far been limited ...

INTRODUCTION: Coccidioidomycosis is an emerging fungal infection caused by inhalation of airborne spores of the Coccidioides genus. While Coccidioides immitis has been detected in soils across California, successful recovery of C. immitis from air samples has so far been limited ...

Harmful cyanobacterial blooms are becoming more common and persistent around the world. When in bloom, various cyanobacterial strains can produce anatoxins in high concentrations, which, unlike other cyanobacterial toxins, may be present in clear water. Potential human and animal...

Background and Purpose:&nbsp; Consumer products are a major source of chemical exposure and therefore potential risk. It is important to understand what chemicals are typically present in various types of products for risk evaluation and assessment of new products for uncommon ch...

Background and Purpose The U.S. Environmental Protection Agency&rsquo;s (U.S. EPA) Toxicity Values Database (ToxValDB) is a compendium of toxicology information including human health reference values, cancer slope factors, ecological screening or effect levels, and quantitative ...

Background and Purpose: Current in vitro toxicology methods typically rely on exposure of cells to compounds that were added to the culture media. For neurotoxicity, in vitro exposure of rat cortical neural networks plated on multi-well microelectrode array plates (MEAs) have bee...

Presentation to Gaining Confidence in NGRA Approaches Together: A DyNAMic DiscussionNURATM Physicians Committee for Responsible Medicine / Institute for In Vitro Sciences Hosted Webinar

The OECD Omics Reporting Framework (OORF) was developed to facilitate the regulatory use of omics data from laboratory-based toxicology studies, which is achieved by means of (i) increasing transparency and reproducibility, and (ii) supporting standardization and harmonization. T...