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RECORD NUMBER: 270 OF 964

OLS Field Name OLS Field Data
Main Title Effects of Cell Source, Mouse Strain, and Immunosuppressive Treatment on Production of Virulent and Attenuated Murine Cytomegalovirus.
Author Selgrade, Maryjane K. ; Nedrud, John G. ; Collier, Albert M. ; Gardner, Donald E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-81-107;
Stock Number PB83-189662
Additional Subjects Viruses ; Mice ; Cells(Biology) ; Production ; Reprints ; Immunosuppression ; Murine cytomegalovirus
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NTIS  PB83-189662 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Abstract Murine cytomegalovirus pools from various in vitro and in vivo sources were compared for virulence in suckling mice in an effort to identify the conditions which were necessary for the production of virulent and attenuated viruses. Virus passaged in tracheal ring and salivary gland organ cultures, where virus is produced primarily by epithelial cells, was even more attenuated than virus passaged in mouse embryo fibroblasts. The attenuation observed after passage in all three of these in vitro systems did not appear to be due to defective interfering particles.
Supplementary Notes Pub. in Infection and Immunity, v33 n3 p840-847 Sep 81.
NTIS Title Notes Journal article.
Title Annotations Reprint: Effects of Cell Source, Mouse Strain, and Immunosuppressive Treatment on Production of Virulent and Attenuated Murine Cytomegalovirus.
PUB Date Free Form 1981
Category Codes 6E; 6M; 57J; 57K
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 320323481
Origin NTIS
Type CAT