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OLS Field Name OLS Field Data
Main Title Dendritic Cells [electronic resource] /
Author Lombardi, Giovanna.
Other Authors
Author Title of a Work
Riffo-Vasquez, Yanira.
Publisher Springer Berlin Heidelberg,
Year Published 2009
Call Number RM1-950
ISBN 9783540710295
Subjects Medicine. ; Oncology. ; Immunology. ; Medical laboratories. ; Microbiology. ; Toxicology. ; Medical virology.
Internet Access
Description Access URL
Collation XVI, 353 p. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Biology of Dendritic Cells -- Activation of Dendritic Cells by Toll-Like Receptors and C-Type Lectins -- Dendritic Cell Migration to Peripheral Lymph Nodes -- Dendritic Cells in Viral Infections -- Role of Dendritic Cells in Disease -- Dendritic Cells and their Potential Implication in Pathology and Treatment of Rheumatoid Arthritis -- Lung Dendritic Cells: Targets for Therapy in Allergic Disease -- Dendritic Cells in Rhinitis -- Role of Epidermal Dendritic Cells in Drug-Induced Cutaneous Adverse Reactions -- Manipulation of Dendritic Cells for Immunotherapy -- T Cell Regulatory Plasmacytoid Dendritic Cells Expressing Indoleamine 2,3 Dioxygenase -- Aspirin and the Induction of Tolerance by Dendritic Cells -- Use of Rapamycin in the Induction of Tolerogenic Dendritic Cells -- Handbook of Experimental Pharmacology "Dendritic Cells" -- Induction of Tolerogenic Dendritic Cells by Vitamin D Receptor Agonists -- Use of Adenovirus in Vaccines for HIV -- IFN-alpha in the Generation of Dendritic Cells for Cancer Immunotherapy -- Dendritic Cell-Based Immunotherapy in Myeloid Leukaemia: Translating Fundamental Mechanisms into Clinical Applications. The understanding of the role of dendritic cells (DCs) in immune responses has come a long way since Steinmann and colleagues described these cells in 1972. - tensive research during the intervening period has provided a good understanding of the complexity of the DC system and its pivotal role in immunity. It is also now clearer how different subsets of DCs interact and regulate each other and how DC populations affect the function of other cells of the immune system. The improved understanding of their role in immune response has led to the idea that modulation of DC functions by, for example, pharmacological agents could be used as a pot- tial therapeutic approach in some pathological conditions. The actual applicability and therapeutic potential of all these approaches is yet to be fully demonstrated but nonetheless, animal models of human diseases are proving to be very helpful in the evaluation of manipulated DCs as a new treatment in diseases like cancer, auto- munity or asthma. DCs are integral to the initiation and regulation of immune response (Banchereau et al. 2000). The outcome of antigen presentation by DCs is determined by their maturation status, which can be induced by their interaction with danger signals. To recognise a wide array of pathogen-associated molecular patterns (PAMP), DCs express a number of pattern recognition receptors (PRR) such as Toll-like rec- tors (TLRs) and C-type lectin receptors (CLR) that recognise structural components of pathogens and discriminate between self and non-self molecules.
Place Published Berlin, Heidelberg
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Handbook of Experimental Pharmacology, 188
Alternate Title With contributions by numerous experts
Host Item Entry Springer eBooks
PUB Date Free Form 2009
Series Title Untraced Handbook of Experimental Pharmacology, 188
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20150107021412
Language eng
OCLC Rec Leader 04536nam a22005655i 45