||Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish: Part 1. Pentachlorophenol, 2,4-Dinitrophenol, Tricaine. Methanesulfonate and 1-Octanol.
McKim, J. M. ;
Schmieder, P. K. ;
Carlson, R. W. ;
Hunt, E. P. ;
Niemi, G. J. ;
||Environmental Research Lab.-Duluth, MN. ;Minnesota Univ.-Duluth.
Cardiovascular system ;
Aquatic animals ;
Salmo gairdneri ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||An in vivo fish model was adapted to monitor respiratory-cardivascular responses of spinally transected rainbow trout exposed to acutely toxic aqueous concentrations of two uncouplers of oxidative phosphorylation, pentachlorophenol (PCP) and 2,4-dinitrophenol (DNP), and two narcotics, tricaine methanesulfonate (MS-222) and 1-octanol. Individual principal component analyses of the cardiovascular-respiratory responses of fish exposed to the first two principal conponents explained 68 to 76% of the variation in the 18 parameters analyzed. The general sets of responses described for these two fish acute toxicity syndromes have provided the initial information necessary to group similar responses caused by other chemicals into a fish uncoupler syndrome, a fish narcosis syndrome or some new syndrome. (Copyright (c) Environmental Toxicology and Chemistry Vol. 6, pp. 295-312, 1987, Pergamon Journals, Ltd.)
||Pub. in Environmental Toxicology and Chemistry, v6 p295-312 Apr 87. See also PB88-107073. Prepared in cooperation with Minnesota Univ.-Duluth.
|NTIS Title Notes
||Reprint: Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish: Part 1. Pentachlorophenol, 2,4-Dinitrophenol, Tricaine. Methanesulfonate and 1-Octanol.
|PUB Date Free Form
||68G; 57H; 57Y; 57Z
||PC A03/MF A01