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OLS Field Name OLS Field Data
Main Title Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish Part 3. Polar Narcotics.
Author Bradbury, S. P. ; Henry, T. R. ; Niemi, G. J. ; Carlson, R. W. ; Snarski, V. M. ;
CORP Author Environmental Research Lab.-Duluth, MN.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/012;
Stock Number PB89-236335
Additional Subjects Toxicity ; Fresh water fishes ; Enzyme inhibitors ; Cardiovascular system ; Phenol ; Trout ; Intoxication ; Tremors ; Respiration ; Anilines ; Animal physiology ; Exposure ; Cholinesterase inhibitors ; Reprints ; Salmo gairdneri
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-236335 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 12/18/1989
Collation 17p
Abstract The physiological responses of rainbow trout to acutely lethal aqueous concentrations of the suspected polar narcotics phenol, 2,4-dimethylphenol, aniline, 2-chloroaniline and 4-chloroaniline were examined. Visible signs of intoxication included tremors that progressed to whole-organism clonic seizures, followed by general depression and respiratory-cardiovascular collapse. Tremors and seizures were usually initiated with coughs. The most striking changes in the respiratory-cardiovascular parameters for all five toxicants included elevated cough frequency (coincident with seizures), ventilation frequency and hematocrit, and depressed gill oxygen uptake efficiency, arterial pH, total arterial oxygen and total arterial carbon dioxide. The physiological responses noted were attributed to the initial muscular activity associated with seizures followed by respiratory-cardiovascular collapse. Using phenol as a model compound, these effects were found to be reversible when intoxicated fish were exposed to chemical-free water. Principal components analyses of the physiological responses demonstrated that the 11 monitored variables were highly correlated.
Supplementary Notes Pub. in Environmental Toxicology and Chemistry, v8 p247-261, 1989. See also PB88-107073.
NTIS Title Notes Journal article.
Title Annotations Reprint: Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish Part 3. Polar Narcotics.
Category Codes 57Y; 57Z; 57H
NTIS Prices PC A03/MF A01
Primary Description 600/03
Document Type NT
Cataloging Source NTIS/MT
Control Number 930024484
Origin NTIS
Type CAT