||Concentration and Toxicity of Trifluralin in CD-1 Mice, Presented Intragastrically of Intraperitoneally.
Beck, Sidney L. ;
||Wheaton Coll., Norton, MA. Dept. of Biology.;Health Effects Research Lab., Research Triangle Park, NC.
Lethal dose ;
Laboratory animals ;
Parenteral infusions ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||This report presents the results of experiments involving administration of the herbicide Trifluralin, dissolved in corn oil, delivered at different concentrations for each dose, either by intragastric intubation or intraperitoneal injection. The investigations produced several surprising results. These included the fact that, in per ora administration there were clear cut differences in toxicity such that for each dose which did cause death, there was inverse relationship between toxicity and concentration. This relationship was not seen in the intraperitoneal treatment groups. Further, there was no apparent difference in LD-50 in the two routes, and the time to death was greater in the intraperitoneally treated animals.
||Pub. in Bulletin of Environmental Contamination and Toxicology, v20 p554-560 1978.
|NTIS Title Notes
||Reprint: Concentration and Toxicity of Trifluralin in CD-1 Mice, Presented Intragastrically of Intraperitoneally.
|PUB Date Free Form
||PC A02/MF A01