Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 86 OF 415

OLS Field Name OLS Field Data
Main Title Changes of Purine Metabolism in Man and Animals Under Conditions of Molybdenum Biogeochemical Provinces (Izmeneniya Purinovogo Obmena u Cheloveka i Zhivotnykh v Usloviyakh Molibdenovykh Biogeokhimicheskikh Provintsii).
Author Kovalskii, V. V. ; Yarovaya, G. A. ; Shmavonyan., D. M. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1961
Report Number EPA-TR-76-362;
Stock Number PB-258 789-T
Additional Subjects Toxicity ; Molydenum ; Purines ; Toxicology ; Nitrogen heterocyclic compounds ; Metals ; Metabolism ; Xanthine oxidase ; Uric acid ; Biochemistry ; Soils ; Ecology ; Contaminants ; Food chains ; Animals ; Humans ; USSR ; Translations ;
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-258 789-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 28p
Abstract Sickness of animals with molybdenosis, caused by an excess molybdenum content in pasture plants, is encountered in England, Canada, USA, New Zealand and other countries. This sickness is characterized by diarrhea, loss of weight and change in color and falling out of the fleece. After it became known that molybdenum is a part of the enzyme xanthine oxidase, it could be assumed that the purine metabolism in an animal organism is disrupted in biogeochemical provinces enriched in molybdenum. With increase in molybdenum content of animal tissues, xanthine oxidase synthesis increases, which results in increased formation of uric acid in the organism and, under certain conditions, it can cause a gout type of sickness. The studies conducted enabled the question to be raised of the effect of the increased molybdenum concentration in the environment on human purine metabolism.
Supplementary Notes Trans. of Zhurnal Obshchei Biologii (USSR) v22 n3 p179-191 1961.
Title Annotations +++Changes of Purine Metabolism in Man and Animals Under Conditions of Molybdenum Biogeochemical Provinces (Izmeneniya Purinovogo Obmena u Cheloveka i Zhivotnykh v Usloviyakh Molibdenovykh Biogeokhimicheskikh Provintsii)--Translation.
PUB Date Free Form 1961
Category Codes 6T; 6F
NTIS Prices PC A03/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323702230
Origin NTIS
Type CAT