Main Title |
Description and Implications for Analysis of Brain Growth in Suckling Mice. |
Author |
House, D. E. ;
Berman, E. ;
Carter, H. B. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/445; |
Stock Number |
PB86-244209 |
Additional Subjects |
Brains ;
Central nervous system ;
Mice ;
Laboratory animals ;
Growth ;
Statistical analysis ;
Regression analysis ;
Reprints ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-244209 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
16p |
Abstract |
The growth pattern of the brains of normal CD-1 mice was studied from day 1 through day 21 after birth. The main purpose of the study was to decide on suitable methods of statistical analysis of these kinds of data including whether to analyze brain weight or the brain-to-body weight ratio. A secondary purpose, which aided the main purpose, was to find functions that describe the relationships between growth parameters. Linear-linear segmented polynomials were found to describe well the relationships between (a) brain weight and body weight, (b) brain weight and age, (c) brain-to-body weight ratio and body weight and (d) brain-to-body weight ratio and age. The analyses indicated that brain weight alone is the preferred variable to analyze. Regression analysis of brain weight with sex and up to the first three powers of body weight and age as independent variables would be a suitable method of analysis. Litter size per se had no effect on brain weight. |
Supplementary Notes |
Pub. in Growth 49, p426-438 1985. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Description and Implications for Analysis of Brain Growth in Suckling Mice. |
PUB Date Free Form |
c1985 |
Category Codes |
6P; 57S |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
631016068 |
Origin |
NTIS |
Type |
CAT |