Main Title |
Preparation of Research Reagents for 2 Dengue Strains. |
Author |
Shope., Robert E. ;
|
CORP Author |
Yale Univ., New Haven, Conn. Yale Arbovirus Research Unit.;National Institutes of Health, Bethesda, Md.;National Inst. of Allergy and Infectious Diseases, Bethesda, Md. Research Resources Branch. |
Year Published |
1976 |
Report Number |
N01-AI-2-2509; NIAID/RR/F-2509-76; |
Stock Number |
PB-257 364 |
Additional Subjects |
Dengue virus ;
Arboviruses ;
Antibodies ;
Antigens ;
Standards ;
Mice ;
Viruses ;
Serology ;
Research ;
Reagents ;
Ascitic fluid
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-257 364 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
14p |
Abstract |
Four lots totalling 3,050 ml of dengue 2 mouse immune ascitic fluid; 5 lots totalling 3,365 ml of dengue 3 immune ascitic fluid; and two lots of 200 ml each of control ascitic fluids were prepared. Plaque reduction neutralization tests indicated that most lots of dengue 2 fluids had homologous neutralization about 32-fold greater than heterologous. Dengue 3 fluids were less specific, with homologous titers 4-8 fold greater than heterologous. Seed virus reagents for dengue 2 and dengue 3 viruses had titers of 9.0 log LD50/ml and 7.0 log LD50/ml respectively. Control ascitic fluids did not neutralize dengue viruses. |
NTIS Title Notes |
Final rept. 28 Feb 72-27 Aug 73. |
PUB Date Free Form |
9 Apr 76 |
Category Codes |
6M; 57K |
NTIS Prices |
PC A02/MF A01 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
326627280 |
Origin |
NTIS |
Type |
CAT |