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OLS Field Name OLS Field Data
Main Title Exposure of Humans to a Volatile Organic Mixture. 2. Sensory.
Author Hudnell, H. K. ; Otto, D. A. ; House, D. E. ; Molhave., L. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Aarhus Univ. (Denmark). Inst. for Miljoe- og Arbejdsmedicin.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-92/118;
Stock Number PB92-164888
Additional Subjects Air pollution effects(Humans) ; Psychomotor performance ; Senses ; Signs and symptoms ; Toxicology ; Questionnaires ; Potentiometry ; Mixtures ; Indoor air pollution ; Trigeminal nerve ; Reprints ; Volatile organic compounds ; Sick building syndrome
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NTIS  PB92-164888 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/28/1992
Collation 11p
Abstract Time-course functions for symptoms of the sick building syndrome were derived from 66 healthy males exposed to clean air and a volatile organic compound (VOC) mixture in separate sessions. The mixture contained 22 VOCs (25 mg/cu m total concentration) commonly found air-borne in new or recently renovated buildings. Subjects rated the intensity of perceived irritation, odor, and other variables before and twice during 2.75 hr exposure periods. Eye and throat irritation, headache, and drowsiness increased or showed no evidence of adaptation during exposure, whereas odor intensity decreased by 30%. These results indicate that irritation intensity and other symptoms are not related in any simple fashion to odor intensity, suggesting that the symptoms may not be a psychosomatic response to detection of an aversive odor. Instead, subthreshold levels of VOCs may interact additively or hyperadditively and stimulate trigeminal nerve receptors.
Supplementary Notes Pub. in Archives of Environmental Health, v47 n1 p31-38 Feb 92. See also PB90-186438. Portions of this document are not fully legible. Prepared in cooperation with Aarhus Univ. (Denmark). Inst. for Miljoe- og Arbejdsmedicin.
NTIS Title Notes Journal article.
Title Annotations Reprint: Exposure of Humans to a Volatile Organic Mixture. 2. Sensory.
Category Codes 68G; 68A; 57Y; 57S
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 212829251
Origin NTIS
Type CAT