Main Title |
Theory and Mathematical Methods for Bioinformatics [electronic resource] / |
Type |
EBOOK |
Author |
Shen, Shiyi.
|
Other Authors |
|
Publisher |
Springer Berlin Heidelberg, |
Year Published |
2008 |
Call Number |
QH324.2-324.25 |
ISBN |
9783540748915 |
Subjects |
Life sciences ;
Human genetics ;
Proteomics ;
Bioinformatics ;
Genetics--Mathematics ;
Biomedical engineering
|
Internet Access |
|
Collation |
XVI, 445 p., 47 illus. online resource. |
Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
Contents Notes |
Outline -- Outline -- Mutations and Alignments -- Stochastic Models of Mutations and Structural Analysis -- Modulus Structure Theory -- Super Pairwise Alignment -- Multiple Sequence Alignment -- Network Structures of Multiple Sequences Induced by Mutation -- Alignment Space -- Protein Configuration Analysis -- Background Information Concerning the Properties of Proteins -- Informational and Statistical Iterative Analysis of Protein Secondary Structure Prediction -- Three-Dimensional Structure Analysis of the Protein Backbone and Side Chains -- Alignment of Primary and Three-Dimensional Structures of Proteins -- Depth Analysis of Protein Spatial Structure -- Analysis of the Morphological Features of Protein Spatial Structure -- Semantic Analysis for Protein Primary Structure. This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics. |
Place Published |
Berlin, Heidelberg |
Corporate Au Added Ent |
SpringerLink (Online service) |
Title Ser Add Ent |
Biological and Medical Physics, Biomedical Engineering, |
Host Item Entry |
Springer eBooks |
PUB Date Free Form |
2008 |
Series Title Untraced |
Biological and Medical Physics, Biomedical Engineering, |
BIB Level |
m |
Medium |
computer |
Content |
text |
Carrier |
online resource |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20131220034047 |
Language |
eng |
Origin |
SPRINGER |
Type |
EBOOK |
OCLC Rec Leader |
03683nam a22005415i 45 |