Main Title |
Predicting chemical toxicity and fate / |
Other Authors |
|
Publisher |
CRC Press, |
Year Published |
2004 |
OCLC Number |
54073110 |
ISBN |
0415271800; 9780415271806; 0415271819; 9780415271813 |
Subjects |
Molecular toxicology ;
Toxicological chemistry ;
QSAR (Biochemistry) ;
Toxicologia ;
Toxicologia (métodos) ;
âEcotoxicologie ;
Toxicologie molculaire ;
Chimie toxicologique ;
Impact environnemental ;
Impact sur la santé ;
Produit chimique ;
Relations quantitatives structure-activité (Biochimie) ;
Toxicity ;
Chemicals ;
Pharmacologic Actions--toxicity ;
Environmental Pollutants--toxicity ;
Quantitative Structure-Activity Relationship ;
Toxicology--methods ;
Chemical Actions--toxicity ;
Toxicologie molâeculaire ;
Impact sur la santâe ;
Relations quantitatives structure-activitâe (Biochimie) ;
Toxicologia (mâetodos)
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJEM |
RA1220.3.P74 2004 |
|
OCSPP Chemical Library/Washington,DC |
09/09/2005 |
EKBM |
RA1220.3.P74 2004 |
|
Research Triangle Park Library/RTP, NC |
05/19/2006 |
EKCM |
RA1220.3.P74 2004 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
05/21/2019 |
EKDM |
RA1220.3.P74 2004 |
|
CEMM/EPD Library/Athens,GA |
10/29/2012 |
STATUS |
ERAM |
RA1220.3.P74 2004 |
|
Region 9 Library/San Francisco,CA |
07/21/2014 |
|
Collation |
445 pages : illustrations ; 26 cm |
Notes |
Includes bibliographical references and index. |
Contents Notes |
Ch. 1. Predicting chemical toxicity and fate in humans and the environment -- an introduction / Mark T.D. Cronin -- Ch. 2. Toxicity data sources / Klaus L.E. Kaiser -- Ch. 3. Calculation of physicochemical properties / Mark T.D. Cronin and David J. Livingstone -- Ch. 4. Good practice in physicochemical property prediction / Peter R. Fisk, Louise McLaughlin and Rosalind J. Wildey -- Ch. 5. Whole molecule and atom-based topological descriptors / Tatiana I. Netzeva -- Ch. 6. Quantum chemical descriptors in structure-activity relationships -- calculation, interpretation, and comparison of methods / Gerrit Schuurmann -- Ch. 7. Building QSAR models : a practical guide / David J. Livingstone -- Ch. 8. Prediction of human health endpoints : mutagenicity and carcinogenicity / Romualdo Benigni -- Ch. 9. The use of expert systems for toxicity prediction : illustrated with reference to the DEREK program / Robert D. Combes and Rosemary A. Rodford -- Ch. 10. Computer-based methods for the prediction of chemical metabolism and biotransformation within biological organisms / Martin P. Payne -- Ch. 11. Prediction of pharmacokinetic parameters in drug design and toxicology / Judith C. Duffy -- Ch. 12. Development and evaluation of QSARs for exotoxic endpoints : the benzene response-surface model for tetrahymena toxicity / T. Wayne Schultz and Tatiana I. Netzeva -- Ch. 13. Receptor-mediated toxicity : QSARs for estrogen receptor binding and priority setting of potential estrogenic endocrine disruptors / Weida Tong, Hong Fang, Huixiao Hong, Qian Xie, Roger Perkins and Daniel M. Sheehan -- Ch. 14. Prediction of persistence / Monika Nendza -- Ch. 15. QSAR modeling of bioaccumulation / John C. Dearden -- Ch. 16. QSAR modeling of soil sorption / John C. Dearden -- Ch. 17. Application of catabolic-based biosensors to develop QSARs for degradation / Graeme I. Paton, Jacob G. Bundy, Colin D. Campbell and Helena Maciel -- Ch. 18. The tiered approach to toxicity assessment based on the integrated use of alternative (non-animal) tests / Andrew P. Worth -- Ch. 19. The use by governmental regulatory agencies of quantitative structure-activity relationships and expert systems to predict toxicity / Mark T.D. Cronin -- Ch. 20. A framework for promoting the acceptance and regulatory use of (quantitative) structure-activity relationships / Andrew P. Worth, Mark T.D. Cronin and Cornelius J. Van Leeuwen. |
Place Published |
Boca Raton, Fla. |
PUB Date Free Form |
©2004 |
BIB Level |
m |
Medium |
unmediated |
Content |
text |
Carrier |
volume |
Cataloging Source |
OCLC/T |
LCCN |
2004043999 |
Merged OCLC records |
1049833484 |
OCLC Time Stamp |
20190515072453 |
Language |
eng |
Origin |
OCLC |
Type |
CAT |
OCLC Rec Leader |
05358cam 22007694a 45010 |