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OLS Field Name OLS Field Data
Main Title Immunology and Psychiatry From Basic Research to Therapeutic Interventions / [electronic resource] :
Other Authors
Author Title of a Work
Müller, Norbert.
Myint, Aye-Mu.
Schwarz, Markus J.
Publisher Springer International Publishing : Imprint: Springer,
Year Published 2015
Call Number RC321-580
ISBN 9783319136028
Subjects Medicine. ; Immunology. ; Neurosciences. ; Psychiatry.
Internet Access
Description Access URL
Collation XIV, 408 p. 17 illus., 13 illus. in color. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Part I. Basic Science -- 1: Animal models based on immune challenge: the links to brain changes and psychiatric disorders -- 2: The prenatal immune activation model for schizophrenia and the role of stress in puberty -- 3: Rodent models of stress induced depression: the link between stress and immune system related changes -- 4. Experimental Human Endotoxemia, Sickness Behavior and Neuropsychiatric Diseases -- Part II. Translational Medicine -- 5. Mild encephalitis theory of psychiatric disorders -- 6. The role of Infection and autoimmune disorders for schizophrenia and depression: Consequences from a large-scale epidemiological study -- 7. Exposure to microorganisms and adult psychiatric disorders: proofs for causal relationship -- 8. Depression: From activation of immune-inflammatory pathways to oxidative-stress-induced autoimmune responses and neuroprogression -- 9. Immune system related markers changes in childhood neuropsychiatric disorders: cause and consequence -- 10. Cytokines and related metabolic biomarkers in adult neuropsychiatric disorders: possible roles in clinical application -- 11. Immune system changes play a role in the development of the metabolic syndrome in psychiatric disorders -- 12. The activation of microglia in severe neuropsychiatric disorders: Focus on infectious mechanisms and PET imaging -- 13. The role of inflammation in Tourette's Syndrome -- 14. The role of inflammation in Autism -- 15. The role of inflammation in Alzheimer's Disease -- Part III: Therapeutic application -- 16. Antidepressants: influence on immune system related parameters -- 17. Cyclooxygenase-2 inhibition in management of depression and schizophrenia -- 18. Poly-unsaturated fatty-acids in management of adult psychiatric disorders. Psychiatric disorders are one of the most dramatic burdens for humankind. The role of immune dysfunction in the pathophysiology of these disorders has emerged during the last years, because there has been tremendous progress in psychoneuroimmunological research. Many results are presented here by pioneers in the field. The book addresses various effects of the immune system on the pathophysiology and course of psychiatric disorders and highlights the possible future impact on treatment decisions of various psychiatric disorders, including schizophrenia and depression. The contributions cover the role of in utero immune challenges on the development of schizophrenia, the role of infections, and autoimmune diseases and mild immune activation in the development of depression and schizophrenia, the influence of immune responses in other disorders such as Tourette's, Alzheimer's, and OCD, the connections between mental and physical pain as well as between anti-inflammatory and antipsychotic drugs.
Place Published Cham
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Current Topics in Neurotoxicity, 8
Host Item Entry Springer eBooks
PUB Date Free Form 2015
Series Title Untraced Current Topics in Neurotoxicity, 8
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20150519184742
Language eng
OCLC Rec Leader 04468nam a22004935i 45