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OLS Field Name OLS Field Data
Main Title Background document on the development and use of reference doses /
Author ENVIRON Corporation. ; Rubenstein, R. ; Rubenstein, Reva.
CORP Author ENVIRON Corp., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Solid Waste.
Publisher U.S. Environmental Protection Agency, Office of Solid Waste,
Year Published 1985
Report Number EPA 530-SW-86-048
Stock Number PB87-107173
OCLC Number 822029115
Subjects Hazardous wastes--Law and legislation--United States. ; Hazardous wastes--Waste disposal--Environmental aspects--United States.
Additional Subjects Solid waste disposal ; Hazardous materials ; Toxicity ; Data collection ; Doses ; Protocols
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 530-SW-86-048 Headquarters Library/Washington,DC 08/15/2013
EJBD  EPA 530-SW-86-048 Headquarters Library/Washington,DC 12/26/2012
NTIS  PB87-107173 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/22/2019
Collation 60, 22 leaves ; 29 cm
Abstract PART I: The Office of Solid Waste (OSW) of EPA proposed certain restrictions on the land disposal of hazardous wastes. To ensure protection of human health, OSW proposed to place limits on the extent of air and water contamination that may result from long-term, law-level releases of hazardous chemicals from land disposal sites. The two principal determinants of these limits are risk-specific doses (RSDs) and reference doses (RFDs). PART II: A discussion of the various considerations influencing the design of protocols for toxicity testing, provided to guide identification of the most cost-effective means to collect toxicity data, is presented in Part II of this report. Specifically, the options available for selecting the species and sex, and species number, number of dose levels, sample size, and extent of animal examination toward the end of identifying the minimally-acceptable protocol for conducting a required toxicity test are examined.
Notes December 20, 1985. NTIS: PB87-107-173.
Contents Notes Part I: Data needs and apportionment -- Part II: Considerations related to the development of protocols for toxicity studies.
Place Published Washington, D.C.,
Supplementary Notes Sponsored by Environmental Protection Agency, Washington, DC. Office of Solid Waste.
Corporate Au Added Ent United States. Office of Solid Waste.
PUB Date Free Form 1985
BIB Level m
Medium microform
Cataloging Source OCLC/T
OCLC Time Stamp 20121219112116
Language eng
Origin OCLC
OCLC Rec Leader 01200nam 2200277Ka 45020