Main Title |
Analytical Isolation, Separation and Identification of Mutagens from Nonvolatile Organics of Drinking Water. |
Author |
Tabor, M. W. ;
Loper, J. C. ;
|
CORP Author |
Cincinnati Univ., OH. Dept. of Environmental Health.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1985 |
Report Number |
EPA-R-808603; EPA/600/J-85/146; |
Stock Number |
PB86-101110 |
Additional Subjects |
Potable water ;
Water analysis ;
Mutagens ;
Bioassay ;
Separation ;
Chemical analysis ;
Water pollution ;
Distillation ;
Industrial wastes ;
Rivers ;
Aquifers ;
Hazardous materials ;
Concentration(Composition) ;
Reprints ;
Water pollution detection ;
XAD resins
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-101110 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
38p |
Abstract |
A general procedure has been developed for the concentration/fractionation of mutagenic residue organics from small, <50L, and large, to 1200L, volumes of drinking water obtained from a variety of sources. This procedure features concentration of the residue organics chromatographically by passage of the water through XAD-2 and XAD-7 resins in specially designed columns, details of which are given. The residue organics are eluted from the resins via organic solvents, followed by solvent removal and subsequent bioassay for mutagenicity. Then the residue organics are fractionated via a coupled bioassay/analytical fractionation method which progressively focuses to the bioactive constituents of the complex mixture of residue organics. In this report, results for the optimal operation and validation of the concentration system are given, using drinking water derived from an industrially polluted river system, a wilderness river system and a major aquifer sytem. The methodologies described in this paper provide a comprehensive approach for the concentration/isolation of residue organics from drinking water for studies to identify biohazardous compounds and to characterize these compounds biologically. |
Availability Notes |
Pub. in International Jnl. of Environmental Analytical Chemistry 19, n4 p281-317 1985. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Analytical Isolation, Separation and Identification of Mutagens from Nonvolatile Organics of Drinking Water. |
PUB Date Free Form |
c1985 |
Category Codes |
7D; 6A; 13B; 68D; 99A; 57B; 50B |
NTIS Prices |
Not available NTIS |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
535324647 |
Origin |
NTIS |
Type |
CAT |