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OLS Field Name OLS Field Data
Main Title Effects of Transplacental Exposure to Chlorinated Phenols.
Author Exon, Jerry H. ; Koller, Loren D. ;
CORP Author Idaho Univ., Moscow.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-R-807267; EPA-600/J-81-373;
Stock Number PB83-187914
Additional Subjects Toxicology ; Placenta ; Rats ; Exposure ; Pregnancy ; Bioassay ; Reproduction(Biology) ; Reprints ; Chlorophenols ; Pentachlorophenol
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NTIS  PB83-187914 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 6p
Abstract Female rats were exposed to 0,5,50 or 500 ppm of 2-Chlorophenol (2CP) or pentachlorophenol (PCP). The study was designed to produce progeny which were exposed to the chlorophenolic compounds both prenatally and postnatally. Percent conception, litter size, birth weight, and number of stillbirths was determined at parturition. Hematologic parameters and body weights of the progeny were recorded at weaning age (3 weeks). Effects on reproduction were observed in both the 2-CP and PCP-exposed groups, as indicated by decreased litter sizes and increased number of stillborn. The data indicate that these chlorinated phenolic compounds may be feto- or embryotoxic at high doses. Effects on hematologic parameters were not observed. Further study involving transplacental and chronic exposures to these chlorophenolic compounds appears warranted.
Supplementary Notes Pub. in Environmental Health Perspectives, v46 p137-140 1982.
NTIS Title Notes Journal article.
Title Annotations Reprint: Effects of Transplacental Exposure to Chlorinated Phenols.
PUB Date Free Form 1982
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 320321898
Origin NTIS
Type CAT