| Main Title |
Synaptic Plasticity and the Mechanism of Alzheimer's Disease [electronic resource] / |
| Type |
EBOOK |
| Author |
Selkoe, Dennis J.
|
| Other Authors |
|
| Publisher |
Springer Berlin Heidelberg, |
| Year Published |
2008 |
| Call Number |
RC321-580 |
| ISBN |
9783540763307 |
| Subjects |
Medicine ;
Human physiology ;
Neurosciences
|
| Internet Access |
|
| Collation |
XII, 183 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
Permanence of the Synapse and Molecular Instability -- Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity -- Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo -- Synapse Loss, Synaptic Plasticity and the Postsynaptic Density -- Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity -- Quantitative Neuropathology in Alzheimer's Mouse Models -- Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States -- Soluble Oligomers of the Amyloid ?-Protein: Impair Synaptic Plasticity and Behavior -- Why Alzheimer's is a Disease of Memory: Synaptic Targeting by Pathogenic A? Oligomers (ADDLs) -- Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-? Levels -- A?-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP) -- Long-Term Potentiation and A?: Targeting A? Species, Cellular Mechanisms and Putative Receptors -- Genes, Synapses and Autism Spectrum Disorders. (will follow) |
| Place Published |
Berlin, Heidelberg |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
Research and Perspectives in Alzheimer's Disease, |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2008 |
| Series Title Untraced |
Research and Perspectives in Alzheimer's Disease, |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20131218054054 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
02655nam a22004695i 45 |
