Main Title |
Acute Toxicity of Monochlorophenols, Dichlorophenols and Pentachlorophenol in the Mouse. |
Author |
Borzelleca, J. F. ;
Hayes, J. R. ;
Condie, L. W. ;
Egle, J. L. ;
|
CORP Author |
Medical Coll. of Virginia, Richmond. Dept. of Pharmacology and Toxicology.;Health Effects Research Lab., Cincinnati, OH. |
Year Published |
1985 |
Report Number |
EPA-R-808861; EPA/600/J-85/352; |
Stock Number |
PB86-175478 |
Additional Subjects |
Toxicity ;
Phenols ;
Bioassay ;
Mice ;
Laboratory animals ;
Dosage ;
Chlorine organic compounds ;
Reprints ;
Phenol/dichloro ;
Phenol/monochloro ;
Phenol/pentachloro
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-175478 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
6p |
Abstract |
Acute oral LD50 values were determined for 2-, 3-, and 4-chlorophenol; 2,3-, 2,4-, 2,5-, 2,6-, 3,4-, and 3,5 dichlorophenol and pentachlorophenol in male and female mice. LD50 values (mg/kg) ranged from 117 (females) and 177 (males) for pentachlorophenol to 2389 (females) and 2643 (males) for 3,5-dichlorophenol. It was found that 2-chlorophenol and 3-chlorophenol were considerably more toxic than the dichlorophenol series. Values for males and females were generally similar, the major differences being with pentachlorophenol and 2,5-dichlorophenol where in both cases the female LD50 was lower. |
Supplementary Notes |
Pub. in Toxicology Letters, v29 n1 p39-42 Dec 85. Sponsored by Health Effects Research Lab., Cincinnati, OH. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Acute Toxicity of Monochlorophenols, Dichlorophenols and Pentachlorophenol in the Mouse. |
PUB Date Free Form |
c1985 |
Category Codes |
6T; 57Y; 68G |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/10 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
614222741 |
Origin |
NTIS |
Type |
CAT |